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result(s) for
"Levitt, Peter"
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The Marseille caper
Sam's last adventure sent him to France in search of a missing wine collection, but he thought it'd be a while before he was back, especially with the charms of the fiery Elena Morales to keep him settled in Los Angeles. But when the immensely wealthy Francis Reboul, the recent victim of Sam's own counter-heist, asks him to take a job in Marseille, it's impossible for Sam and Elena to resist. The lure of further excitement and the pleasures of the region beckon them back to France. Quelle joie! Yet as competition over Marseille's valuable waterfront grows more hotly disputed, Sam, representing Reboul, finds himself right in the middle, with intrigue and danger following closely behind.
Single-molecule analysis of steroid receptor and cofactor action in living cells
by
Morisaki, Tatsuya
,
Paakinaho, Ville
,
Johnson, Thomas A.
in
14/63
,
631/57/2265
,
Adaptor Proteins, Signal Transducing - metabolism
2017
Population-based assays have been employed extensively to investigate the interactions of transcription factors (TFs) with chromatin and are often interpreted in terms of static and sequential binding. However, fluorescence microscopy techniques reveal a more dynamic binding behaviour of TFs in live cells. Here we analyse the strengths and limitations of
in vivo
single-molecule tracking and performed a comprehensive analysis on the intranuclear dwell times of four steroid receptors and a number of known cofactors. While the absolute residence times estimates can depend on imaging acquisition parameters due to sampling bias, our results indicate that only a small proportion of factors are specifically bound to chromatin at any given time. Interestingly, the glucocorticoid receptor and its cofactors affect each other’s dwell times in an asymmetric manner. Overall, our data indicate transient rather than stable TF-cofactors chromatin interactions at response elements at the single-molecule level.
Transcription factors (TFs) are thought to regulate gene expression by stably binding to target DNA elements. Here, the authors use single-molecule tracking to analyse the dynamic behaviour of steroid receptors TFs and show that most specific interactions with chromatin are transient and dynamic.
Journal Article
The Screen Door Slams
2005
Peter Levitt: in addition to eight books of poetry, Peter Levitt has published fiction, essays, and translations from Chinese, Japanese and Spanish. He received the Lannan Foundation Award in Poetry in 1989.
Journal Article
Zucchini and Peach
2005
No one knows. And if no one knows then no one will know. No eyes will see no ears will hear when there is nothing to see and nothing to hear. And when there is something to see and something to hear, still no one knows, not really, sometimes even when it is happening to them. Touch, but don't look. Kiss, but don't tell. Hide, but don't seek. Kill, but don't feel. Every child is raised in this prison one way or another. I know a man who told me that when he was a boy a neighbourhood man with a metal plate in his head from the Korean War took him to a field pulled his pants down and told him Kiss it! He couldn't get kiss and it together. Kiss was the soft skin of his mother's cheek, the smell of his father's cigarettes. No. Kiss it. No. Just put it in your hand and give it a little squeeze. No. He ran to the man's car and grabbed a hammer he had seen on the floor a hammer like the one his father used to build everything the first time a hammer ever turned into a weapon in his hands so he knew for the first time too that sometimes things were not themselves and as the man ran toward him calling him scumbag calling him punk calling him chicken shouting I'm going to tell everyone that you did it you little shit he swung the hammer at the man's head where he thought the metal plate might be as hot bombs exploded out of his eyes and he swung it again and again. That was fifty years ago. No act, he said, not even a simple one is free from the olive colour of his skin, the stench of his breath, the bristle of his wiry beard. All of it now a pathway of the mind, and not mine alone, for I have told it to you. I'm sorry.
Journal Article
A Translation in Winter
2005
Peter Levitt: in addition to eight books of poetry, Peter Levitt has published fiction, essays, and translations from Chinese, Japanese and Spanish. He received the Lannan Foundation Award in Poetry in 1989. His most recent books are Fingerpainting on the Moon, (Random House), and A Flock of Fools: Ancient Buddhist Tales of Wisdom and Laughter (Grove Press), which he translated and retold with Kazuaki Tanahashi. This year he hopes to complete manuscripts for a new book of poetry, and Petit Chapeau, a book of what he calls 'short poetic fictions'.
Journal Article
The Lens
2005
Peter Levitt: in addition to eight books of poetry, Peter Levitt has published fiction, essays, and translations from Chinese, Japanese and Spanish. He received the Lannan Foundation Award in Poetry in 1989. His most recent books are Fingerpainting on the Moon, (Random House), and A Flock of Fools: Ancient Buddhist Tales of Wisdom and Laughter (Grove Press), which he translated and retold with Kazuaki Tanahashi. This year he hopes to complete manuscripts for a new book of poetry, and Petit Chapeau, a book of what he calls 'short poetic fictions'.
Journal Article
the fires within
1994
When I was a child, I sang this version of the nursery rhyme. It always frightened me to think of the last two lines. I used to imagine the terror in the poor ladybug's heart. I used to picture her fleeing through the air, more lightning bug or firefly than ladybug, to save her children from the deadly flames. Any parent would certainly do the same. Anyone, for that matter, would do whatever was needed to put out the fire. Wouldn't they?...
Newspaper Article