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"Lewis, W."
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Exploitation-Exploration Tensions and Organizational Ambidexterity: Managing Paradoxes of Innovation
Achieving exploitation and exploration enables success, even survival, but raises challenging tensions. Ambidextrous organizations excel at exploiting existing products to enable incremental innovation and at exploring new opportunities to foster more radical innovation, yet related research is limited. Largely conceptual, anecdotal, or single case studies offer architectural or contextual approaches. Architectural ambidexterity proposes dual structures and strategies to differentiate efforts, focusing actors on one or the other form of innovation. In contrast, contextual approaches use behavioral and social means to integrate exploitation and exploration. To develop a more comprehensive model, we sought to learn from five, ambidextrous firms that lead the product design industry. Results offer an alternative framework for examining exploitation-exploration tensions and their management. More specifically, we present nested paradoxes of innovation: strategic intent (profit-breakthroughs), customer orientation (tight-loose coupling), and personal drivers (discipline-passion). Building from innovation and paradox literature, we theorize how integration and differentiation tactics help manage these interwoven paradoxes and fuel virtuous cycles of ambidexterity. Further, managing paradoxes becomes a shared responsibility, not only of top management, but across organizational levels.
Journal Article
Multispectral graphene-based electro-optical surfaces with reversible tunability from visible to microwave wavelengths
Optical materials with colour changing abilities have been explored for use in display devices1, smart windows2,3 or in the modulation of visual appearance4–6. The efficiency of these materials, however, has strong wavelength dependence, which limits their functionality to a specific spectral range. Here, we report graphene-based electro-optical devices with unprecedented optical tunability covering the entire electromagnetic spectrum from the visible to microwave. We achieve this non-volatile and reversible tunability by electro-intercalation of lithium into graphene layers in an optically accessible device structure. The unique colour changing capability, together with area-selective intercalation, inspires the fabrication of new multispectral devices, including display devices and electro-optical camouflage coating. We anticipate that these results provide realistic approaches for programmable smart optical surfaces with a potential utility in many scientific and engineering fields such as active plasmonics and adaptive thermal management.By converting Li-ion battery into an optical device using graphene electrodes, an electrochemical optical device which enables colour changing ability over the entire wavelength range from visible to microwave is demonstrated.
Journal Article
Relational spirituality : a psychological-theological paradigm for transformation
\"Human beings are fundamentally relational-we develop, heal, and grow through relationships. Integrating insights from psychology and theology, Todd W. Hall and M. Elizabeth Lewis Hall present a definitive model of spiritual transformation based on a relational paradigm, showing how transformation works practically in the context of relationships and community\"-- Provided by publisher.
BOOK
Guideline of transthyretin-related hereditary amyloidosis for clinicians
Transthyretin amyloidosis is a progressive and eventually fatal disease primarily characterized by sensory, motor, and autonomic neuropathy and/or cardiomyopathy. Given its phenotypic unpredictability and variability, transthyretin amyloidosis can be difficult to recognize and manage. Misdiagnosis is common, and patients may wait several years before accurate diagnosis, risking additional significant irreversible deterioration. This article aims to help physicians better understand transthyretin amyloidosis—and, specifically, familial amyloidotic polyneuropathy—so they can recognize and manage the disease more easily and discuss it with their patients. We provide guidance on making a definitive diagnosis, explain methods for disease staging and evaluation of disease progression, and discuss symptom mitigation and treatment strategies, including liver transplant and several pharmacotherapies that have shown promise in clinical trials.
Journal Article
Beyond Rosie : a documentary history of women and World War II
\"More so than any war in history, World War II was a woman's war. Women, motivated by patriotism, the opportunity for new experiences, and the desire to serve, participated widely in the global conflict. Within the Allied countries, women of all ages proved to be invaluable in the fight for victory. Rosie the Riveter became the most enduring image of women's involvement in World War II. What Rosie represented, however, is only a small portion of a complex story. As wartime production workers, enlistees in auxiliary military units, members of voluntary organizations or resistance groups, wives and mothers on the home front, journalists, and USO performers, American women found ways to challenge traditional gender roles and stereotypes. Beyond Rosie offers readers an opportunity to see the numerous contributions women made to the fight against the Axis powers and how American women's roles changed during the war. The primary documents (newspapers, propaganda posters, cartoons, excerpts from oral histories and memoirs, speeches, photographs, and editorials) collected here represent cultural, political, economic, and social perspectives on the diverse roles women played during World War II.\"--Page 4 of cover.
Book
High frequency body site translocation of nosocomial Pseudomonas aeruginosa
Pseudomonas aeruginosa
is an important nosocomial pathogen which can cause serious infections across diverse anatomic locations. Infections can spread within an individual to different body sites, but the rate and directionality of this process is unknown. Here, we explore within-host diversity as well as the body site translocation dynamics using de-convoluted metagenomic
P. aeruginosa
reads from 256 hospital patients sampled at both respiratory and gut sites. Of the 84 patients where
P. aeruginosa
genomes could be recovered, there were 27 cases where the same
P. aeruginosa
clone was detected across multiple body sites. Using a simulation approach, we find that the majority of body site sharing is likely due to within-patient translocation of clones rather than independent acquisition from the hospital environment. Using ancestral reconstruction, we predict that most clones likely occupied a respiratory niche, and that the probable direction of clone transmission is lung-to-gut. Analysis of within-patient variation highlights strong enrichment of mutations in genes associated with antimicrobial resistance, irrespective of sample type. We report significantly more translocation than has been previously reported and highlight that lower respiratory tract infections can result in persistent gut colonisation of
P. aeruginosa
, a major risk factor for sepsis in vulnerable patients.
Here, the authors report within-host diversity and body site translocation dynamics in hospital samples of
Pseudomonas aeruginosa
and reveal that body site sharing was likely due to within-patient translocation rather than independent acquisition.
Journal Article
Who is government? : the untold story of public service
\"The government is a vast, complex system that Americans pay for, rebel against, rely upon, dismiss, and celebrate. It's also our shared resource for addressing the biggest problems of society. And it's made up of people, mostly unrecognized and uncelebrated, doing work that can be deeply consequential and beneficial to everyone. Michael Lewis invited his favorite writers to find someone doing an interesting job for the government and write about them in a special in-depth series for the Washington Post. The stories they found are unexpected, riveting, and inspiring, including a former coal miner devoted to making mine roofs less likely to collapse, saving thousands of lives; an IRS agent straight out of a crime thriller; and the manager who made the National Cemetery Administration the best-run organization, public or private, in the entire country. Each essay shines a spotlight on the essential behind-the-scenes work of exemplary federal employees. Whether they're digitizing archives, chasing down cybercriminals, or discovering new planets, these public servants are committed to their work and universally reluctant to take credit. Expanding on the Washington Post series, the vivid profiles in Who Is Government? blow up the stereotype of the irrelevant bureaucrat. They show how the essential business of government makes our lives possible, and how much it matters\"-- Provided by publisher.
BOOK
Electron-scale measurements of magnetic reconnection in space
Magnetic reconnection is a fundamental physical process in plasmas whereby stored magnetic energy is converted into heat and kinetic energy of charged particles. Reconnection occurs in many astrophysical plasma environments and in laboratory plasmas. Using measurements with very high time resolution, NASA's Magnetospheric Multiscale (MMS) mission has found direct evidence for electron demagnetization and acceleration at sites along the sunward boundary of Earth's magnetosphere where the interplanetary magnetic field reconnects with the terrestrial magnetic field. We have (i) observed the conversion of magnetic energy to particle energy; (ii) measured the electric field and current, which together cause the dissipation of magnetic energy; and (iii) identified the electron population that carries the current as a result of demagnetization and acceleration within the reconnection diffusion/dissipation region.
Journal Article