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"Li, Chengliang"
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Tuan yuan
Maomao's dad can only come back home once a year because of the work. In Chinese New Year, they have a good time for their family reunion.
Book
Effect of the Modifications on the Physicochemical and Biological Properties of β-Glucan—A Critical Review
β-Glucan exhibits many biological activities and functions such as stimulation of the immune system and anti-inflammatory, anti-microbial, anti-infective, anti-viral, anti-tumor, anti-oxidant, anti-coagulant, cholesterol-lowering, radio protective, and wound healing effects. It has a wide variety of uses in pharmaceutical, cosmetic, and chemical industries as well as in food processing units. However, due to its dense triple helix structure, formed by the interaction of polyhydroxy groups in the β-d-glucan molecule, it features poor solubility, which not only constrains its applications, but also inhibits its physiological function in vivo. One aim is to expand the applications for modified β-glucan with potential to prevent disease, various therapeutic purposes and as health-improving ingredients in functional foods and cosmetics. This review introduces the major modification methods required to understand the bioactivity of β-glucan and critically provides a literature survey on the structural features of this molecule and reported biological activity. We also discuss a new method to create novel opportunities to exploit maximally various properties of β-glucan, namely ultrasound-assisted enzymatic modification.
Journal Article
A review on the production, structure, bioactivities and applications of Tremella polysaccharides
Tremella polysaccharide is known to be structurally unique and biologically active natural products, abundant and versatile in activities and applications in food industry, daily chemical industry and medicine industry. In order to improve the industrialisation of Tremella polysaccharide, the limitations of preparation and structure-activity relationship of Tremella polysaccharide were reviewed in this paper. The research progress of Tremella polysaccharide in the past 20 years was summarized from the sources, preparation methods, molecular structure, activity and application, and the research trend in the future was also prospected. The application prospect of Tremella polysaccharide in against multiple sub-health states was worth expecting.
Journal Article
Exploration of the potential association between GLP-1 receptor agonists and suicidal or self-injurious behaviors: a pharmacovigilance study based on the FDA Adverse Event Reporting System database
Background
Establishing whether there is a potential relationship between glucagon-like peptide 1 receptor agonists (GLP-1RAs) and suicidal or self-injurious behaviors (SSIBs) is crucial for public safety. This study investigated the potential association between GLP-1RAs and SSIBs by exploring the FDA Adverse Event Reporting System (FAERS) database.
Methods
A disproportionality analysis was conducted using post-marketing data from the FAERS repository (2018 Q1 to 2022 Q4). SSIB cases associated with GLP-1RAs were identified and analyzed through disproportionality analysis using the information component. The parametric distribution with a goodness-of-fit test was employed to analyze the time-to-onset, and the Ω shrinkage was used to evaluate the potential effect of co-medication on the occurrence of SSIBs.
Results
In total, 204 cases of SSIBs associated with GLP-1RAs, including semaglutide, liraglutide, dulaglutide, exenatide, and albiglutide, were identified in the FAERS database. Time-of-onset analysis revealed no consistent mechanism for the latency of SSIBs in patients receiving GLP-1RAs. The disproportionality analysis did not indicate an association between GLP-1RAs and SSIBs. Co-medication analysis revealed 81 cases with antidepressants, antipsychotics, and benzodiazepines, which may be proxies of mental health comorbidities.
Conclusions
We found no signal of disproportionate reporting of an association between GLP-1RA use and SSIBs. Clinicians need to maintain heightened vigilance on patients premedicated with neuropsychotropic drugs. This contributes to the greater acceptance of GLP-1RAs in patients with type 2 diabetes mellitus or obesity.
Graphical Abstract
Highlights
• To determine whether there is a potential relationship between glucagon-like peptide 1 receptor agonists (GLP-1RAs) and suicidal or self-injurious behaviors (SSIBs).
• Is there a direct association between GLP-1RAs and SSIBs? No evidence reasonably suggests an association between GLP-1RAs and SSIBs based on clinical characteristics, time-onset, disproportionality, and co-medication analysis.
• Clinicians should pay more attention to the psychiatric status of patients with a history of neuropsychotropic drugs, and more comprehensive monitoring is needed to consider their susceptibility to SSIBs carefully.
Journal Article
Biochar derived from corn straw affected availability and distribution of soil nutrients and cotton yield
Biochar application as a soil amendment has been proposed as a strategy to improve soil fertility and increase crop yields. However, the effects of successive biochar applications on cotton yields and nutrient distribution in soil are not well documented. A three-year field study was conducted to investigate the effects of successive biochar applications at different rates on cotton yield and on the soil nutrient distribution in the 0-100 cm soil profile. Biochar was applied at 0, 5, 10, and 20 t ha-1 (expressed as Control, BC5, BC10, and BC20, respectively) for each cotton season, with identical doses of chemical fertilizers. Biochar enhanced the cotton lint yield by 8.0-15.8%, 9.3-13.9%, and 9.2-21.9% in 2013, 2014, and 2015, respectively, and high levels of biochar application achieved high cotton yields each year. Leaching of soil nitrate was reduced, while the pH values, soil organic carbon, total nitrogen (N), and available K content of the 0-20 cm soil layer were increased in 2014 and 2015. However, the changes in the soil available P content were less substantial. This study suggests that successive biochar amendments have the potential to enhance cotton productivity and soil fertility while reducing nitrate leaching.
Journal Article
From Polyester Plastics to Diverse Monomers via Low‐Energy Upcycling
Polyester plastics, constituting over 10% of the total plastic production, are widely used in packaging, fiber, single‐use beverage bottles, etc. However, their current depolymerization processes face challenges such as non‐broad spectrum recyclability, lack of diversified high‐value‐added depolymerization products, and crucially high energy consumption. Herein, an efficient strategy is developed for dismantling the compact structure of polyester plastics to achieve diverse monomer recovery. Polyester plastics undergo swelling and decrystallization with a low depolymerization energy barrier via synergistic effects of polyfluorine/hydrogen bonding, which is further demonstrated via density functional theory calculations. The swelling process is elucidated through scanning electron microscopy analysis. Obvious destruction of the crystalline region is demonstrated through X‐ray crystal diffractometry curves. PET undergoes different aminolysis efficiently, yielding nine corresponding high‐value‐added monomers via low‐energy upcycling. Furthermore, four types of polyester plastics and five types of blended polyester plastics are closed‐loop recycled, affording diverse monomers with exceeding 90% yields. Kilogram‐scale depolymerization of real polyethylene terephthalate (PET) waste plastics is successfully achieved with a 96% yield. Polyester plastics undergo swelling and decrystallization with a low depolymerization energy barrier via synergistic effects of polyfluorine/hydrogen bonding by TFA. TFA‐treated polyester undergoes different aminolysis, yielding nine corresponding high‐added‐value chemicals. Furthermore, four polyester plastics and five blended polyester plastics are closed‐loop recycled efficiently, Kilogram‐scale depolymerization of real mixed PET waste plastics is achieved with 96% yield.
Journal Article
Acute effects of vibration foam rolling and local vibration during warm-up on athletic performance in tennis players
Athletes are currently fond of vibration foam rollers (VFRs) and commercial portable vibration percussion devices (PVPDs). It is still unknown whether using these devices during warm-up has an immediate impact on athletic performance. A randomized block design was used in this study. The acute effects of VFR and PVPD on tennis players’ athletic performance during warm-up were compared. For the countermovement jump (CMJ), reactive strength index (RSI), and hexagon test (HT), the difference in performance between all interventions was significant (p = 0.007–0.034, η 2 p = 0.266–0.364). Only those who received VFR had significantly different CMJ and HT results when compared to the control group (CMJ height = 53.18 ±4.49 cm, p = 0.03, d = 1.26; HT time = 10.73 ±0.4 s, p = 0.03, d = 1.12). Participants’ RSI values were significantly different after VFR (RSI = 2.01 ±0.11 cm·mm –1 , p = 0.012, d = 1.76) and PVPD (RSI = 1.99 ±0.11 cm·mm –1 , p = 0.025, d = 1.52) compared to the control group. Therefore, when using VFR and PVPD as part of warm-up protocols for tennis players of varying skill levels, VFR could have an immediate positive effect on power, reactive strength, and change of direction performance, while PVPD could immediately improve reactive strength performance.
Journal Article
Controlled Release Urea Improved Nitrogen Use Efficiency and Yield of Wheat and Corn
Nitrogen fertilizer is important for improving wheat (Triticum aestivum L.) and corn (Zea mays L.) yields, but inappropriate application methods and excessive amounts lead to low N use efficiency and high N losses through leaching. To investigate the effects of controlled‐release urea (CRU) on crop yield and soil fertility, a field experiment was conducted from 2012 to 2014 in China. The 100% (180 kg ha−1) and 70% (126 kg ha−1) of the local practice N rates with CRU and urea were used. The results revealed that the release curves of CRU in the natural field corresponded well to the N requirements of wheat and corn plants, and a positive linear correlation was observed between release rates and days after buried in soil. Consequently, the CRU treatments achieved significantly higher wheat and corn yield by 8 to 12% and 9 to 11%, respectively, compared with urea treatments at the same N rate. Reducing N rate of CRU by 30% produced the same yield as with the 100% N rate of urea. The agronomic nitrogen use efficiency (NUE) was significantly increased and the leaching of soil N was reduced by CRU. The acidification rates and leaching of exchangeable Ca2+, K+, Na+ contents were reduced, base saturation and available P improved by application of CRU compared with urea. Therefore, the results suggested that a 30% decrease of CRU in the recommended application rate of N, can be an effective measure to save consumption input of N fertilizer. Core Ideas Nitrogen release rates of controlled‐release urea in field condition corresponded well to the N uptake of crop plants. A 30% decrease in the application rate of N is possible with controlled‐release urea compared to urea. The application of controlled‐release urea increased crop yield, N use efficiency, net farm profit, and soil fertility.
Journal Article
Spatial Distribution, Key Influencing Factors, and Ecological Risk of Microplastics in Pearl River Estuary Water and Sediments
Microplastic (MP) pollution in aquatic ecosystems poses significant ecological and public health risks. A comprehensive understanding of estuarine MP pollution, influenced by multiple anthropogenic and environmental factors, remains elusive in current research. This study investigated the spatial distribution patterns and dominant factors influencing MP abundance (MPA) and physicochemical diversity in the river water and sediments of the Pearl River Estuary (PRE), while also assessing the associated ecological risks. The dominant MP categories in river water and sediments were fibers, clear in color, <1 mm in length, and composed of polyethylene terephthalate and polypropylene. Whereas inland regions showed higher MPA, nearshore regions exhibited marginally greater physicochemical diversity. Multivariate statistical analysis identified population density as the primary driver of both MPA in river water and MP physicochemical diversity in sediments. MP physicochemical diversity in river water was predominantly governed by the synergistic effect of salinity and the vegetation land. MPA in sediments depended on the synergistic effect of flow rate and watershed area. Ecological risk assessment identified elevated risks in the eastern study area driven by the presence of polymethyl methacrylate. This study establishes a scientific basis for PRE region MP management and provides global comparative data for estuarine MP research.
Journal Article