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"Li, Ting"
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ESG: Research Progress and Future Prospects
2021
The sustainable development of the global economy and society calls for the practice of the environmental, social and governance (ESG) principle. The ESG principle has been developed for 17 years following its formal proposal in 2004. Countries around the world continue to promote the coordinated development of the environment, society, and governance in accordance with the ESG principle. In order to review and summarize ESG research, this study takes the literature related to ESG research as the research object and presents the cooperation status, hot spots, and trends of ESG research with the help of the literature analysis tool CiteSpace. On the basis of quantitative analysis results, this study presents an examination and comprehensive summary of progress in the research into ESG combined with a systematic literature review. This includes the theoretical basis of ESG research, the interaction between the dimensions of ESG, the impact of ESG on the economic consequences, the risk prevention role of ESG, and ESG measurement. Based on the systematic summary of research progress, this paper further refines the characteristics of ESG research, reveals the shortcomings of ESG research, and propose a focus for ESG research in the future in order to provide a reference for academic research and the practice of ESG.
Journal Article
MOF‐on‐MOF‐Derived Hollow Co3O4/In2O3 Nanostructure for Efficient Photocatalytic CO2 Reduction
2023
The photocatalytic transformation of carbon dioxide (CO2) into carbon‐based fuels or chemicals using sustainable solar energy is considered an ideal strategy for simultaneously alleviating the energy shortage and environmental crises. However, owing to the low energy utilization of sunlight and inferior catalytic activity, the conversion efficiency of CO2 photoreduction is far from satisfactory. In this study, a MOF‐derived hollow bimetallic oxide nanomaterial is prepared for the efficient photoreduction of CO2. First, a unique ZIF‐67‐on‐InOF‐1 heterostructure is successfully obtained by growing a secondary Co‐based ZIF‐67 onto the initial InOF‐1 nanorods. The corresponding hollow counterpart has a larger specific surface area after acid etching, and the oxidized bimetallic H‐Co3O4/In2O3 material exhibits abundant heterogeneous interfaces that expose more active sites. The energy band structure of H‐Co3O4/In2O3 corresponds well with the photosensitizer of [Ru(bpy)3]Cl2, which results in a high CO yield of 4828 ± 570 µmol h−1 g−1 and stable activity over a consecutive of six runs, demonstrating adequate photocatalytic performance. This study demonstrates that the rational design of MOF‐on‐MOF heterostructures can completely exploit the synergistic effects between different components, which may be extended to other MOF‐derived nanomaterials as promising catalysts for practical energy conversion and storage. In this article, the hollow counterpart of H‐ZIF‐67‐on‐InOF‐1 presents a larger specific surface area after being acid‐etched, and its corresponding bimetallic oxide of H‐Co3O4/In2O3 owns abundant heterogeneous interfaces, which show a satisfactory photocatalytic CO2 reduction.
Journal Article
MAGdb: a comprehensive high quality MAGs repository for exploring microbial metagenome-assemble genomes
by
Meng, Zhi-Tong
,
Zhou, Tao
,
Wu, Jia-Qi
in
Animal Genetics and Genomics
,
Bacteria
,
Bioinformatics
2025
Metagenomic analyses of microbial communities have unveiled a substantial level of interspecies and intraspecies genetic diversity by reconstructing metagenome-assembled genomes (MAGs). The MAG database (MAGdb) boasts an impressive collection of 74 representative research papers, spanning clinical, environmental, and animal categories and comprising 13,702 paired-end run accessions of metagenomic sequencing and 99,672 high quality MAGs with manually curated metadata. MAGdb provides a user-friendly interface that users can browse, search, and download MAGs and their corresponding metadata information. It represents a valuable resource for researchers in discovering potential novel microbial lineages and understanding their ecological roles. MAGdb is publicly available at
https://magdb.nanhulab.ac.cn/
.
Journal Article
Enhancing enterprise knowledge retrieval via cross-domain deep recommendation: a sparse data approach
Enterprise knowledge retrieval faces challenges like sparse data and inefficient cross-domain knowledge transfer, hindering traditional methods. To address this, we develop a cross-domain recommendation model (CDR-VAE), combining a hybrid autoencoder with domain alignment, and test its effectiveness on an enterprise dataset and the Movies&Books benchmark. At a top-5 recommendation length, CDR-VAE scores HR = 0.642, Recall = 0.432, NDCG = 0.715, outperforming existing models. Removing shared latent representations reduces HR to 0.701, proving their necessity for cross-domain learning. In enterprise applications, high-activity users favor technical reports (0.903), while low-activity users shift toward cross-domain content like industry standards (0.701), confirming the model’s robustness in sparse scenarios. CDR-VAE successfully tackles sparsity and cross-domain barriers, advancing enterprise knowledge management. This work provides theoretical and practical insights for deep learning-based recommendation systems in data-scarce environments.
Journal Article
Interaction between macrophages and ferroptosis
2022
Ferroptosis, a newly discovered iron-dependent cell death pathway, is characterized by lipid peroxidation and GSH depletion mediated by iron metabolism and is morphologically, biologically and genetically different from other programmed cell deaths. Besides, ferroptosis is usually found accompanied by inflammatory reactions. So far, it has been found participating in the development of many kinds of diseases. Macrophages are a group of immune cells that widely exist in our body for host defense and play an important role in tissue homeostasis by mediating inflammation and regulating iron, lipid and amino acid metabolisms through their unique functions like phagocytosis and efferocytosis, cytokines secretion and ROS production under different polarization. According to these common points in ferroptosis characteristics and macrophages functions, it’s obvious that there must be relationship between macrophages and ferroptosis. Therefore, our review aims at revealing the interaction between macrophages and ferroptosis concerning three metabolisms and integrating the application of certain relationship in curing diseases, mostly cancer. Finally, we also provide inspirations for further studies in therapy for some diseases by targeting certain resident macrophages in distinct tissues to regulate ferroptosis.
Facts
Ferroptosis is considered as a newly discovered form characterized by its nonapoptotic and iron-dependent lipid hydroperoxide, concerning iron, lipid and amino acid metabolisms.
Ferroptosis has been widely found playing a crucial part in various diseases, including hepatic diseases, neurological diseases, cancer, etc.
Macrophages are phagocytic immune cells, widely existing and owning various functions such as phagocytosis and efferocytosis, cytokines secretion and ROS production.
Macrophages are proved to participate in mediating metabolisms and initiating immune reactions to maintain balance in our body.
Recent studies try to treat cancer by altering macrophages’ polarization which damages tumor microenvironment and induces ferroptosis of cancer cells.
Open questions
How do macrophages regulate ferroptosis of other tissue cells specifically?
Can we use the interaction between macrophages and ferroptosis in treating diseases other than cancer?
What can we do to treat diseases related to ferroptosis by targeting macrophages?
Is the use of the relationship between macrophages and ferroptosis more effective than other therapies when treating diseases?
Journal Article
The Gossypium hirsutum TIR‐NBS‐LRR gene GhDSC1 mediates resistance against Verticillium wilt
by
Liu, Ting‐Li
,
Subbarao, Krishna V.
,
Wang, Dan
in
Acid resistance
,
Analysis
,
Arabidopsis thaliana
2019
Summary Improving genetic resistance is a preferred method to manage Verticillium wilt of cotton and other hosts. Identifying host resistance is difficult because of the dearth of resistance genes against this pathogen. Previously, a novel candidate gene involved in Verticillium wilt resistance was identified by a genome‐wide association study using a panel of Gossypium hirsutum accessions. In this study, we cloned the candidate resistance gene from cotton that encodes a protein sharing homology with the TIR‐NBS‐LRR receptor‐like defence protein DSC1 in Arabidopsis thaliana (hereafter named GhDSC1). GhDSC1 expressed at higher levels in response to Verticillium wilt and jasmonic acid (JA) treatment in resistant cotton cultivars as compared to susceptible cultivars and its product was localized to nucleus. The transfer of GhDSC1 to Arabidopsis conferred Verticillium resistance in an A. thaliana dsc1 mutant. This resistance response was associated with reactive oxygen species (ROS) accumulation and increased expression of JA‐signalling‐related genes. Furthermore, the expression of GhDSC1 in response to Verticillium wilt and JA signalling in A. thaliana displayed expression patterns similar to GhCAMTA3 in cotton under identical conditions, suggesting a coordinated DSC1 and CAMTA3 response in A. thaliana to Verticillium wilt. Analyses of GhDSC1 sequence polymorphism revealed a single nucleotide polymorphism (SNP) difference between resistant and susceptible cotton accessions, within the P‐loop motif encoded by GhDSC1. This SNP difference causes ineffective activation of defence response in susceptible cultivars. These results demonstrated that GhDSC1 confers Verticillium resistance in the model plant system of A. thaliana, and therefore represents a suitable candidate for the genetic engineering of Verticillium wilt resistance in cotton.
Journal Article
Prevalence of human infection with respiratory adenovirus in China: A systematic review and meta-analysis
by
Xu, Qiang
,
Liu, Wei
,
Fang, Li-Qun
in
Adenoviridae Infections - epidemiology
,
Adenovirus diseases
,
Adenovirus Infections, Human - diagnosis
2023
Human adenovirus (HAdV) is a major pathogen that causes acute respiratory tract infections (ARTI) and is frequently associated with outbreaks. The HAdV prevalence and the predominant types responsible for ARTI outbreaks remains obscure in China.
A systematic review was performed to retrieve literature that reported outbreaks or etiological surveillance of HAdV among ARTI patients in China from 2009 to 2020. Patient information was extracted from the literature to explore the epidemiological characteristics and clinical manifestations of the infection of various HAdV types. The study is registered with PROSPERO, CRD42022303015.
A total of 950 articles (91 about outbreaks and 859 about etiological surveillance) meeting the selection criteria were included. Predominant HAdV types from etiological surveillance studies differed from those in outbreak events. Among 859 hospital-based etiological surveillance studies, positive detection rates of HAdV-3 (32.73%) and HAdV-7 (27.48%) were significantly higher than other virus types. While nearly half (45.71%) of outbreaks were caused by HAdV-7 with an overall attack rate of 22.32% among the 70 outbreaks for which the HAdVs were typed by the meta-analysis. Military camp and school were main outbreak settings with significantly different seasonal pattern and attack rate, where HAdV-55 and HAdV-7 were identified as the leading type, respectively. Clinical manifestations mainly depended on the HAdV types and patient's age. HAdV-55 infection tends to develop into pneumonia with poorer prognosis, especially in children <5 years old.
This study improves the understanding of epidemiological and clinical features of HAdV infections and outbreaks with different virus types, and helps to inform future surveillance and control efforts in different settings.
Journal Article
Jasmonic Acid Impairs Arabidopsis Seedling Salt Stress Tolerance Through MYC2-Mediated Repression of CAT2 Expression
2021
High salinity causes ionic, osmotic, and oxidative stresses to plants, and the antioxidant enzyme Catalase2 (CAT2) plays a vital role in this process, while how CAT2 expression is regulated during plant response to high salinity remains elusive. Here, we report that phytohormone jasmonic acid (JA) impairs plant salt stress tolerance by repressing CAT2 expression in an MYC2-dependent manner. Exogenous JA application decreased plant salt stress tolerance while the jar1 mutant with reduced bioactive JA-Ile accumulation showed enhanced salt stress tolerance. JA enhanced salt-induced hydrogen peroxide (H 2 O 2 ) accumulation, while treatment with H 2 O 2 -scavenger glutathione compromised such effects of JA on plant H 2 O 2 accumulation and salt stress tolerance. In addition, JA repressed CAT2 expression in salt-stressed wild-type plant but not in myc2 , a mutant of the master transcriptional factor MYC2 in JA signaling, therefore, the myc2 mutant exhibited increased salt stress tolerance. Further study showed that mutation of CAT2 largely reverted lower reactive oxygen species (ROS) accumulation, higher CAT activity, and enhanced salt stress tolerance of the myc2 mutant in myc2 cat2-1 double mutant, revealing that CAT2 functions downstream JA-MYC2 module in plant response to high salinity. Together, our study reveals that JA impairs Arabidopsis seedling salt stress tolerance through MYC2-mediated repression of CAT2 expression.
Journal Article
An Overview of the Mechanisms through Which Plants Regulate ROS Homeostasis under Cadmium Stress
2024
Cadmium (Cd2+) is a non-essential and highly toxic element to all organic life forms, including plants and humans. In response to Cd stress, plants have evolved multiple protective mechanisms, such as Cd2+ chelation, vesicle sequestration, the regulation of Cd2+ uptake, and enhanced antioxidant defenses. When Cd2+ accumulates in plants to a certain level, it triggers a burst of reactive oxygen species (ROS), leading to chlorosis, growth retardation, and potentially death. To counteract this, plants utilize a complex network of enzymatic and non-enzymatic antioxidant systems to manage ROS and protect cells from oxidative damage. This review systematically summarizes how various elements, including nitrogen, phosphorus, calcium, iron, and zinc, as well as phytohormones such as abscisic acid, auxin, brassinosteroids, and ethylene, and signaling molecules like nitric oxide, hydrogen peroxide, and hydrogen sulfide, regulate the antioxidant system under Cd stress. Furthermore, it explores the mechanisms by which exogenous regulators can enhance the antioxidant capacity and mitigate Cd toxicity.
Journal Article
Stringing Bimetallic Metal–Organic Framework‐Derived Cobalt Phosphide Composite for High‐Efficiency Overall Water Splitting
2020
Water electrolysis is an emerging energy conversion technology, which is significant for efficient hydrogen (H2) production. Based on the high‐activity transition metal ions and metal alloys of ultrastable bifunctional catalyst, the hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) are the key to achieving the energy conversion method by overall water splitting (OWS). This study reports that the Co‐based coordination polymer (ZIF‐67) anchoring on an indium–organic framework (InOF‐1) composite (InOF‐1@ZIF‐67) is treated followed by carbonization and phosphorization to successfully obtain CoP nanoparticles–embedded carbon nanotubes and nitrogen‐doped carbon materials (CoP‐InNC@CNT). As HER and OER electrocatalysts, it is demonstrated that CoP‐InNC@CNT simultaneously exhibit high HER performance (overpotential of 153 mV in 0.5 m H2SO4 and 159 mV in 1.0 m KOH) and OER performance (overpotential of 270 mV in 1.0 m KOH) activities to reach the current density of 10 mA cm−2. In addition, these CoP‐InNC@CNT rods, as a cathode and an anode, can display an excellent OWS performance with η10 = 1.58 V and better stability, which shows the satisfying electrocatalyst for the OWS compared to control materials. This method ensures the tight and uniform growth of the fast nucleating and stable materials on substrate and can be further applied for practical electrochemical reactions. A type of CoP embedded in carbon nanotubes and nitrogen‐doped carbon material calcined from a bimetallic metal–organic frameworks (MOF) precursor is designed and prepared by growing Co‐based MOFs on an indium–organic framework. The CoP incorporation can greatly promote the water splitting kinetics by the optimized catalyst of CoP‐InNC@CNT, thus the high electrocatalytic activity is achieved toward both the hydrogen evolution reaction and oxygen evolution reaction.
Journal Article