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1,832 result(s) for "Li, Yu-han"
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Green and software-defined wireless networks : from theory to practice
\"Understand the fundamental theory and practical design aspects of green and soft wireless communications networks with this expert text. It provides comprehensive and unified coverage of 5G physical layer design, as well as design of the higher and radio access layers and the core network, drawing on viewpoints from both academia and industry. Get to grips with the theory through authoritative discussion of information-theoretical results, and learn about fundamental green design trade-offs, software-defined network architectures, and energy-efficient radio resource management strategies. Applications of wireless big data and artificial intelligence to wireless network design are included, providing an excellent design reference, and real-world examples of employment in software-defined 5G networks and energy-saving solutions from wireless communications companies and cellular operators help to connect theory with practice. This is an essential text for graduate students, professionals and researchers\"-- Provided by publisher.
Current understanding of gut microbiota alterations and related therapeutic intervention strategies in heart failure
The purpose of this review is to stress the complicated interactions between the microbiota and the development of heart failure. Moreover, the feasibility of modulating intestinal microbes and metabolites as novel therapeutic strategies is discussed. This study was based on data obtained from PubMed up to March 31, 2019. Articles were selected using the following search terms: \"gut microbiota,\" \"heart failure,\" \"trimethylamine N-oxide (TMAO),\" \"short-chain fatty acid (SCFA),\" \"bile acid,\" \"uremic toxin,\" \"treatment,\" \"diet,\" \"probiotic,\" \"prebiotic,\" \"antibiotic,\" and \"fecal microbiota transplantation.\" Accumulated evidence has revealed that the composition of the gut microbiota varies obviously in people with heart failure compared to those with healthy status. Altered gut microbial communities contribute to heart failure through bacterial translocation or affecting multiple metabolic pathways, including the trimethylamine/TMAO, SCFA, bile acid, and uremic toxin pathways. Meanwhile, modulation of the gut microbiota through diet, pre/probiotics, fecal transplantation, and microbial enzyme inhibitors has become a potential therapeutic approach for many metabolic disorders. Specifically, a few studies have focused on the cardioprotective effects of probiotics on heart failure. The composition of the gut microbiota in people with heart failure is different from those with healthy status. A reduction in SCFA-producing bacteria in patients with heart failure might be a notable characteristic for patients with heart failure. Moreover, an increase in the microbial potential to produce TMAO and lipopolysaccharides is prominent. More researches focused on the mechanisms of microbial metabolites and the clinical application of multiple therapeutic interventions is necessarily required.
Impact of physical exercise on sleep quality in college students: A Chain mediating role of self-efficacy and emotional control
The study aims to examine the impact of physical exercise on sleep quality among college students and elucidate the mediating roles of self-efficacy and emotional control in this relationship. Data were obtained from the 2024 China College Students' Physical Activity and Health Tracking Survey (CPAHLS-CS). A sample of 10,970 college students was included. Physical exercise levels were measured using the Physical Activity Rating Scale-3 (PARS-3), sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI), self-efficacy was measured using the General Self-Efficacy Scale (GSES), and emotional control was assessed using the Adolescent Psychological Resilience Scale. Regression analysis and Bootstrap mediation analysis were employed to test the hypothesised relationships. (1) The direct effect of physical exercise on sleep quality was not significant (β = 0.011, P > 0.05). However, the total effect was negative (β = -0.056, P < 0.001), indicating that indirect effects comprised the predominant mechanism. (2) Self-efficacy (effect size = -0.024) and emotional control (effect size = -0.022) each independently mediated the relationship between physical exercise and sleep quality. (3) In the pathway through which physical exercise influences sleep quality, self-efficacy, and emotional control functioned as independent mediating variables. Specifically, physical exercise indirectly improved sleep quality by enhancing self-efficacy while positively impacting sleep quality through a distinct mediating mechanism involving strengthening emotional control. This study demonstrates the influence of physical exercise, self-efficacy, and emotional control on sleep quality. The findings suggest that physical exercise indirectly optimises sleep quality through a dynamic and synergistic mechanism involving the enhancement of self-efficacy and emotional control. This study provides theoretical support and practical pathways for sleep quality interventions in college students.
The influence of physical activity on emotional management ability in college students: a chain mediating role of psychological resilience and health literacy
Objective This study aimed to investigate the impact of physical activity (PA) on emotional management ability (EMA) in college students and to analyze the chain mediating roles of psychological resilience (PR) and health literacy (HL) in the relationship between PA and EMA. Methods Demographic information was collected using a stratified, cluster, and multi-stage sampling method. Data on PA, PR, HL, and EMA among college students were collected using an online questionnaire. A total of 13,590 valid questionnaires were obtained. Results A significant positive correlation was found between PA and EMA in college students ( r  = 0.177, P  < 0.01). PR and HL played significant mediating roles in the relationship between PA and EMA. The mediation effect consisted of independent mediation by PR and HL and a chain mediation effect between the two. The values of the independent mediation effects and the chain mediation effect were 0.011, 0.010, and 0.004, respectively. The chain mediation effect was lower than each of the individual mediation effects and showed a statistically significant difference compared to the mediation effect of HL ( P  < 0.05). Conclusion PA significantly enhances college students’ EMA through direct effects and a chain mediation pathway involving PR and HL. Coordinated interventions, including regular exercise, PR training, and health education, are recommended to optimize college students’ psychological health.
The influence of physical exercise on emotional management ability in college students: A serial mediation model of exercise adherence and psychological resilience
This study aimed to examine the influence of physical exercise (PE) on emotional management ability (EMA) among college students and to investigate the mediating roles of exercise adherence (EA) and psychological resilience (PR) in the relationship between PE and EMA. Demographic information was collected using stratified, cluster, and multi-stage sampling methods. Data on PE, EA, PR, and EMA were collected from college students via the Wenjuanxing platform, resulting in a final sample of 11,388 valid questionnaires. Significant positive correlations were found between PE and EMA (r = 0.164, P < 0.01), PE and EA (r = 0.452, P < 0.01), and PE and PR (r = 0.201, P < 0.01). Significant positive correlations were also observed between EA and PR (r = 0.329, P < 0.01), and EA and EMA (r = 0.478, P < 0.01). PR was significantly positively correlated with EMA (r = 0.411, P < 0.01). PE significantly negatively predicted EMA (β = -0.009, P < 0.001). EA mediated the relationship between PE and EMA (95% CI: [0.039, 0.045]). PR also mediated the relationship between PE and EMA (95% CI: [0.001, 0.004]). A serial mediation effect of EA and PR was found in the relationship between PE and EMA (95% CI: [0.008, 0.010]). This study reveals the impact of PE, EA, and PR on EMA. The findings suggest that enhancing PE participation, improving EA, and increasing PR can improve EMA among college students.
Evaluating the Suitability of Ground-Mounted Photovoltaic System Selection and the Differences Between Expert Assessments and Firm Location Preferences: A Case Study of Tainan City
Responding to the challenges of global climate change and domestic air pollution, Taiwan revised its energy policy in recent years, introducing an energy transition strategy focused on low-carbon and clean energy. However, if photovoltaic installations are not properly sited, they may have negative impacts on the local environment. Previous research on renewable energy has primarily focused on policy evaluation, with limited attention given to case studies that examine the suitability of site selection for PV system installations. Thus, this study incorporates the Fuzzy Delphi Method (FDM) and the Analytic Hierarchy Process (AHP) to explore the criteria for evaluating site suitability for ground-mounted PV systems. This study considers existing sites with completed ground-mounted PV systems in Tainan City as case study subjects. The results indicate that the most important factor, as prioritized by experts, is the distance from Class I environmentally sensitive areas, followed by the duration of insolation, proximity to the electrical grid, and distance from residential areas. The evaluation model developed in this study provides a valuable reference for future site selection of ground-mounted PV systems. Establishing dedicated PV energy parks also may offer a viable solution to mitigate disputes related to the deployment of ground-mounted PV systems.
Endurance exercise attenuates Gαq-RNAi induced hereditary obesity and skeletal muscle dysfunction via improving skeletal muscle Srl/MRCC-I pathway in Drosophila
G protein alpha q subunit ( Gαq ) can binds to the G protein-coupled receptor (GPCR) for signaling and is closely related to lipid metabolism. Endurance exercise is an effective means of combating acquired obesity and its complications, but the mechanisms by which endurance exercise modulates hereditary obesity and its complications are unknown. In this study, we achieved knockdown of Gαq in drosophila adipose tissue and skeletal muscle by constructing the Gαq-UAS-RNAi/Ppl-Gal4 and Gαq-UAS-RNAi/Mef2-GAl4 systems. Drosophila were subjected a three-week endurance exercise intervention, and changes in relevant indicators were detected and observed by RT-PCR, ELISA, oil red staining, immunofluorescence staining, and transmission electron microscopy. The results showed that knockdown of Gαq in both adipose tissue and skeletal muscle induced a significant increase in triglycerides accompanied by a decrease in rapid climbing ability, a decrease in Superoxide Dismutase (SOD) activity level, and a decrease in Mitochondrial respiratory chain complexI (MRCC I) content in Drosophila whole body and skeletal muscle, and down-regulated the expression of the G protein alpha q subunit ( Gαq ), the skeletal muscle myosin heavy chain expression gene ( Mhc ), mitochondrial biogenesis gene Spargal (the PGC-1alpha homologue in Drosophila). Endurance exercise significantly improved the triglyceride levels in the whole body and skeletal muscle of drosophila with Gαq knockdown in adipose tissue and skeletal muscle, as well as their ability to climb, increased SOD activity level and MRCCI content level, and up-regulated the expression of Gαq , Mhc , and Spargal(Srl) . Thus, the present findings suggest that genetic defects in the Gαq gene in adipose and skeletal muscle tissues induce hereditary obesity and skeletal muscle dysfunction, and that endurance exercise attenuates this hereditary obesity and concomitant skeletal muscle dysfunction in drosophila by improving skeletal muscle fiber contractile proteins, mitochondrial function and function, and antioxidant capacity via mediating the Gαq/Mhc , Gαq/Srl/MRCC-I , and Gαq/SOD pathways.
Morphological and molecular identification of two new Ganoderma species on Casuarina equisetifolia from China
Ganoderma is a cosmopolitan white rot fungal genus, famous for its medicinal properties. In the present study, two new Ganoderma species were collected from south-eastern China and described on the basis of morphological characters and phylogenetic analyses of sequences of the internal transcribed spacer (ITS) region, the translation elongation factor 1-α gene (EF1-α) and the second subunit of RNA polymerase II (RPB2). Specimens of both species were found on living trees of Casuarinaequisetifolia . Ganodermaangustisporum sp. nov. is characterised by its sessile basidiomata and almond-shaped, slightly truncate, narrow basidiospores (9–11.3 × 4–5.2 µm). Ganodermacasuarinicola sp. nov. is characterised by its strongly laccate reddish-brown pileal surface, luminous yellow to yellowish-brown cutis and ellipsoid, truncate basidiospores (9–10.2 × 5–6 µm). The two new species are compared with their related taxa. Phylogenetic analyses confirmed that G.angustisporum and G.casuarinicola are distinct species within Ganoderma .
Rethinking the Influencing Factors of Economic Resilience Under the COVID-19 Pandemic
Along with globalization, frequent and cross-regional transportation has driven the prosperity and development of cities worldwide. Nevertheless, the high density and concentration of urban activities also bring spatial heterogeneity to different cities. Previous research, focusing mainly on the impact of the financial crisis, has indicated that the characteristics of urban zones influence its performance of economic resilience. However, the development duration type and severity of various shocks may differ. This study, based on the perspectives of the COVID-19 pandemic, reviews the effect of various influencing factors, such as the ratio of manufacturing industry, population mobility, investment in R&D by the industries and the completeness of public facilities, on the effect of a shock on economic resilience. The economic resilience of each research target area during the pandemic of 2020 is calculated by applying the index of economic resilience estimated by the changes in consumptions and the analysis of Pearson product-moment correlation coefficient, revealing that a city with a higher ratio of manufacturing industry and investment in R&D has better economic resilience. Conversely, cities with greater population mobility and more areas of public facilities reveal the weakness of economic resilience during the pandemic. Researchers believe that the collapse in consumption of the cities caused by citizens avoiding exposure risks has influenced economic performance. This work shows that the factors of economic resilience vary from shocks. Consequently, policymakers must address the features of shocks when developing relevant policies in response to the shocks.
Prevention of polycystic ovary syndrome and postmenopausal osteoporosis by inhibiting apoptosis with Shenling Baizhu powder compound
Shenling Baizhu powder (SBP) has been shown to reverse the abnormal expression of the aromatic hydrocarbon receptor (AHR) mediated by air pollution. Our study aimed to understand the main ingredient of SBP and investigate its action mechanism in preventing polycystic ovary syndrome (POCS) and postmenopausal osteoporosis (PMO). The active ingredients of SBP with the highest binding affinity to AHR were screened using a Chinese medicine database, and their binding mechanism was simulated using molecular dynamics simulation (MDS). Rutin was utilized to treat ovarian granulosa cell lines and osteoblast cell lines. The cell lines were treated with a gradient of rutin concentration (0.01 mmol/L, 0.05 mmol/L and 0.1 mmol/L) to find the optimal drug dose. PCR was used to detect AHR and apoptosis-related proteins, and WB to detect the expression of AHR, caspase-3 and cleaved-caspase-3. Finally, the CCK-8 cell proliferation assay detected the proliferation of cells. We obtained Rutin through the Chinese medicine database, and dynamics simulation determined its binding sites. Ovarian granulosa cell lines and osteoblast cell lines were treated with Rutin. RT-PCR and western blotting revealed that the expression of apoptosis-associated protein Bcl-2 was elevated, and the expression of AHR, Bax, caspase-3 and PARP were decreased. CCK-8 results showed accelerated proliferation in both cell types. Rutin, the main ingredient of SBP compound, works by binding to AHR, which can improve POCS and PMO by inhibiting cell apoptosis and by promoting cell proliferation.