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Prevalence of Hearing Loss by Severity in the United States
Objectives. To estimate the age- and severity-specific prevalence of hearing impairment in the United States. Methods. We conducted cross-sectional analyses of 2001 through 2010 data from the National Health and Nutrition Examination Survey on 9648 individuals aged 12 years or older. Hearing loss was defined as mild (> 25 dB through 40 dB), moderate (> 40 dB through 60 dB), severe (> 60 dB through 80 dB), or profound (> 80 dB). Results. An estimated 25.4 million, 10.7 million, 1.8 million, and 0.4 million US residents aged 12 years or older, respectively, have mild, moderate, severe, and profound better-ear hearing loss. Older individuals displayed a higher prevalence of hearing loss and more severe levels of loss. Across most ages, the prevalence was higher among Hispanic and non-Hispanic Whites than among non-Hispanic Blacks and was higher among men than women. Conclusions. Hearing loss directly affects 23% of Americans aged 12 years or older. The majority of these individuals have mild hearing loss; however, moderate loss is more prevalent than mild loss among individuals aged 80 years or older. Public Health Implications. Our estimates can inform national public health initiatives on hearing loss and help guide policy recommendations currently being discussed at the Institute of Medicine and the White House.
Journal Article
Leonard Bernstein : a research and information guide
Leonard Bernstein: A Research and Information Guide is an annotated bibliography and research guide on this popular American composer and conductor. It includes annotations on Bernstein's writings, performances, educational work, and major secondary sources. Also included are a biographical sketch, lists of compositions and arrangements, as well as lists of recordings and video. The second edition is updated to include research since the 1st edition was published in 2001, as well as online resources [Publisher description]
BOOK
Fast generation of Schrödinger cat states using a Kerr-tunable superconducting resonator
Schrödinger cat states, quantum superpositions of macroscopically distinct classical states, are an important resource for quantum communication, quantum metrology and quantum computation. Especially, cat states in a phase space protected against phase-flip errors can be used as a logical qubit. However, cat states, normally generated in three-dimensional cavities and/or strong multi-photon drives, are facing the challenges of scalability and controllability. Here, we present a strategy to generate and preserve cat states in a coplanar superconducting circuit by the fast modulation of Kerr nonlinearity. At the Kerr-free work point, our cat states are passively preserved due to the vanishing Kerr effect. We are able to prepare a 2-component cat state in our chip-based device with a fidelity reaching 89.1% under a 96 ns gate time. Our scheme shows an excellent route to constructing a chip-based bosonic quantum processor.
Schrodinger’s cat states constitute an important resource for quantum information processing, but present challenges in terms of scalabilty and controllability. Here, the authors exploit fast Kerr nonlinearity modulation to generate and store cat states in superconducting circuits in a more scalable way.
Journal Article
Energy Release and Particle Acceleration in Flares: Summary and Future Prospects
RHESSI
measurements relevant to the fundamental processes of energy release and particle acceleration in flares are summarized.
RHESSI’s
precise measurements of hard X-ray continuum spectra enable model-independent deconvolution to obtain the parent electron spectrum. Taking into account the effects of albedo, these show that the low energy cut-off to the electron power-law spectrum is typically ≲tens of keV, confirming that the accelerated electrons contain a large fraction of the energy released in flares.
RHESSI
has detected a high coronal hard X-ray source that is filled with accelerated electrons whose energy density is comparable to the magnetic-field energy density. This suggests an efficient conversion of energy, previously stored in the magnetic field, into the bulk acceleration of electrons. A new, collisionless (Hall) magnetic reconnection process has been identified through theory and simulations, and directly observed in space and in the laboratory; it should occur in the solar corona as well, with a reconnection rate fast enough for the energy release in flares. The reconnection process could result in the formation of multiple elongated magnetic islands, that then collapse to bulk-accelerate the electrons, rapidly enough to produce the observed hard X-ray emissions.
RHESSI’s
pioneering
γ
-ray line imaging of energetic ions, revealing footpoints straddling a flare loop arcade, has provided strong evidence that ion acceleration is also related to magnetic reconnection. Flare particle acceleration is shown to have a close relationship to impulsive Solar Energetic Particle (SEP) events observed in the interplanetary medium, and also to both fast coronal mass ejections and gradual SEP events. New instrumentation to provide the high sensitivity and wide dynamic range hard X-ray and
γ
-ray measurements, plus energetic neutral atom (ENA) imaging of SEPs above ∼2 R
⊙
, will enable the next great leap forward in understanding particle acceleration and energy release is large solar eruptions—solar flares and associated fast coronal mass ejections (CMEs).
Journal Article
Association of hearing impairment with brain volume changes in older adults
Hearing impairment in older adults is independently associated in longitudinal studies with accelerated cognitive decline and incident dementia, and in cross-sectional studies, with reduced volumes in the auditory cortex. Whether peripheral hearing impairment is associated with accelerated rates of brain atrophy is unclear. We analyzed brain volume measurements from magnetic resonance brain scans of individuals with normal hearing versus hearing impairment (speech-frequency pure tone average>25dB) followed in the neuroimaging substudy of the Baltimore Longitudinal Study of Aging for a mean of 6.4years after the baseline scan (n=126, age 56–86years). Brain volume measurements were performed with semi-automated region-of-interest (ROI) algorithms, and brain volume trajectories were analyzed with mixed-effect regression models adjusted for demographic and cardiovascular factors. We found that individuals with hearing impairment (n=51) compared to those with normal hearing (n=75) had accelerated volume declines in whole brain and regional volumes in the right temporal lobe (superior, middle, and inferior temporal gyri, parahippocampus, p<.05). These results were robust to adjustment for multiple confounders and were consistent with voxel-based analyses, which also implicated right greater than left temporal regions. These findings demonstrate that peripheral hearing impairment is independently associated with accelerated brain atrophy in whole brain and regional volumes concentrated in the right temporal lobe. Further studies investigating the mechanistic basis of the observed associations are needed.
Journal Article
MAVEN SupraThermal and Thermal Ion Compostion (STATIC) Instrument
The MAVEN SupraThermal And Thermal Ion Compostion (STATIC) instrument is designed to measure the ion composition and distribution function of the cold Martian ionosphere, the heated suprathermal tail of this plasma in the upper ionosphere, and the pickup ions accelerated by solar wind electric fields. STATIC operates over an energy range of 0.1 eV up to 30 keV, with a base time resolution of 4 seconds. The instrument consists of a toroidal “top hat” electrostatic analyzer with a
360
∘
×
90
∘
field-of-view, combined with a time-of-flight (TOF) velocity analyzer with
22.5
∘
resolution in the detection plane. The TOF combines a
−
15
kV
acceleration voltage with ultra-thin carbon foils to resolve
H
+
,
He
+
+
,
He
+
,
O
+
,
O
2
+
, and
CO
2
+
ions. Secondary electrons from carbon foils are detected by microchannel plate detectors and binned into a variety of data products with varying energy, mass, angle, and time resolution. To prevent detector saturation when measuring cold ram ions at periapsis (
∼
10
1
1
eV/cm
2
s
sr
eV
), while maintaining adequate sensitivity to resolve tenuous pickup ions at apoapsis (
∼
10
3
eV/cm
2
s
sr
eV
), the sensor includes both mechanical and electrostatic attenuators that increase the dynamic range by a factor of
10
3
. This paper describes the instrument hardware, including several innovative improvements over previous TOF sensors, the ground calibrations of the sensor, the data products generated by the experiment, and some early measurements during cruise phase to Mars.
Journal Article
Global metrics on ocular biometry: representative averages and standard deviations across ten countries from four continents
Background/Objectives
We provide global averages and standard deviations for ocular biometry—axial length (AL), corneal radius of curvature (CR), anterior chamber depth (ACD), lens thickness (LT), white to white (WTW), and central corneal thickness (CT). We hope a better understanding of normal and abnormal values will help clinicians gain further insight into their surgical outcomes, especially for off-target eyes.
Subjects/Methods
We searched the MEDLINE database using keywords “axial length, corneal power, anterior chamber depth, lens thickness, white to white, and corneal thickness.” We included studies that reported averages and standard deviations on eye biometry for at least 1300 eyes. Global weighted averages and standard deviations were calculated using the Cochrane method.
Results
Fourteen studies were included, originating from Asia (Japan, Singapore, Myanmar, Iran, South Korea, China), Europe (Germany, United Kingdom, Portugal), Australia, and North America (United States). Global ocular biometry metrics were: AL—23.49 mm ± 1.35 mm, CR—7.69 mm ± 0.28 mm, ACD—3.10 mm ± 0.47 mm, WTW—11.80 mm ± 0.42 mm, LT—4.37 mm ± 0.43 mm, and CT—544 μm ± 38 μm. Total eyes per value ranged from 19,538 to 90,814.
Conclusions
We report global ocular biometry averages and standard deviations. No eyes were from studies in Africa or South America, highlighting the need to publish eye biometry data from these continents. We hope that promoting a deeper understanding of biometry values will help clinicians gain insight into surgical outcomes and drive innovations in lens calculations.
Journal Article