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LED packaging for lighting applications
This book is ideal for practicing engineers working in design or packaging at LED companies and graduate students preparing for work in industry. This book also provides a helpful introduction for advanced undergraduates, graduates, researchers, lighting designers, and product managers interested in the fundamentals of LED design and production.
eBook
At home in her tomb : Lady Dai and the ancient Chinese treasures of Mawangdui
\"...unearths the mysteries of the Mawangdui (mah-wahng-dway) tombs, one of China's top archaeological finds of the last century. Miniature servants, mysterious silk paintings, scrolls of long-lost secrets, and the best preserved mummy in the world (the body of Lady Dai) are just some of the artifacts that shed light upon life in China during the Han dynasty.\"--Amazon.com.
Book
The topological counterparts of non-Hermitian SSH models
Inspired by the relevance between the asymmetric coupling amplitude and the imaginary gauge field, we construct the counterpart of the non-Hermitian SSH model. The idea is the nonzero imaginary magnetic flux vanishing when the boundary condition changes from periodic to open. The zero imaginary magnetic flux of the counterpart leads to the eliminating of the non-Hermitian skin effect and the non-Hermitian Aharonov–Bohm effect which ensures the recovery of the conventional bulk-boundary correspondence from the non-Bloch bulk-boundary correspondence. We explain how some the non-Hermitian models can be transformed to the non-Hermitian SSH models and how the non-reciprocal hopping in the non-Hermitian SSH models can be transformed from one term to the other terms by the similarity transformations. We elaborate why the effective imaginary magnetic flux disappears due to the interplay of the non-reciprocal hoppings in the partner of the non-Hermitian SSH model. As the results, we obtain the topological invariants of the non-Hermitian SSH model in analytical form defined in conventional Brillouin zone. The non-Hermitian SSH model in domain configuration on a chain is discussed with this method. The technique gives an alternative way to study the topological properties of non-Hermitian systems.
Journal Article
Long noncoding RNAs in cancer metastasis
Metastasis is a major contributor to cancer-associated deaths. It is characterized by a multistep process that occurs through the acquisition of molecular and phenotypic changes enabling cancer cells from a primary tumour to disseminate and colonize at distant organ sites. Over the past decade, the discovery and characterization of long noncoding RNAs (lncRNAs) have revealed the diversity of their regulatory roles, including key contributions throughout the metastatic cascade. Here, we review how lncRNAs promote metastasis by functioning in discrete pro-metastatic steps including the epithelial–mesenchymal transition, invasion and migration and organotrophic colonization, and by influencing the metastatic tumour microenvironment, often by interacting within ribonucleoprotein complexes or directly with other nucleic acid entities. We discuss well-characterized lncRNAs with in vivo phenotypes and highlight mechanistic commonalities such as convergence with the TGFβ–ZEB1/ZEB2 axis or the nuclear factor-κB pathway, in addition to lncRNAs with controversial mechanisms and the influence of methodologies on mechanistic interpretation. Furthermore, some lncRNAs can help identify tumours with increased metastatic risk and spur novel therapeutic strategies, with several lncRNAs having shown potential as novel targets for antisense oligonucleotide therapy in animal models. In addition to well-characterized examples of lncRNAs functioning in metastasis, we discuss controversies and ongoing challenges in lncRNA biology. Finally, we present areas for future study for this rapidly evolving field.This Review discusses how long noncoding RNAs influence metastasis by functioning in discrete pro-metastatic steps including the epithelial–mesenchymal transition, invasion and migration and organotrophic colonization, and by influencing the tumour microenvironment. Diagnostic and therapeutic potential as well as controversies and ongoing technical challenges are discussed.
Journal Article
The Effect of Exercise Training on Resting Concentrations of Peripheral Brain-Derived Neurotrophic Factor (BDNF): A Meta-Analysis
The mechanisms through which physical activity supports healthy brain function remain to be elucidated. One hypothesis suggests that increased brain-derived neurotrophic factor (BDNF) mediates some cognitive and mood benefits. This meta-analysis sought to determine the effect of exercise training on resting concentrations of BDNF in peripheral blood.
MEDLINE, Embase, PsycINFO, SPORTDiscus, Rehabilitation & Sports Medicine Source, and CINAHL databases were searched for original, peer-reviewed reports of peripheral blood BDNF concentrations before and after exercise interventions ≥ 2 weeks. Risk of bias was assessed using standardized criteria. Standardized mean differences (SMDs) were generated from random effects models. Risk of publication bias was assessed using funnel plots and Egger's test. Potential sources of heterogeneity were explored in subgroup analyses.
In 29 studies that met inclusion criteria, resting concentrations of peripheral blood BDNF were higher after intervention (SMD = 0.39, 95% CI: 0.17-0.60, p < 0.001). Subgroup analyses suggested a significant effect in aerobic (SMD = 0.66, 95% CI: 0.33-0.99, p < 0.001) but not resistance training (SMD = 0.07, 95% CI: -0.15-0.30, p = 0.52) interventions. No significant difference in effect was observed between males and females, nor in serum vs plasma.
Aerobic but not resistance training interventions increased resting BDNF concentrations in peripheral blood.
Journal Article
A view from the stars
A View from the Stars is a collection of short fiction and nonfiction pieces from Cixin Liu, the New York Times bestselling author of The Three-Body Problem. Included are essays and interviews that shed light on Liu's experiences as a reader, writer, and lover of science fiction throughout his life, as well as short fiction that gives glimpses into the evolution of his imaginative voice over the years\"--Back cover.
BOOK
Unusual competition of superconductivity and charge-density-wave state in a compressed topological kagome metal
Understanding the competition between superconductivity and other ordered states (such as antiferromagnetic or charge-density-wave (CDW) state) is a central issue in condensed matter physics. The recently discovered layered kagome metal
A
V
3
Sb
5
(
A
= K, Rb, and Cs) provides us a new playground to study the interplay of superconductivity and CDW state by involving nontrivial topology of band structures. Here, we conduct high-pressure electrical transport and magnetic susceptibility measurements to study CsV
3
Sb
5
with the highest
T
c
of 2.7 K in
A
V
3
Sb
5
family. While the CDW transition is monotonically suppressed by pressure, superconductivity is enhanced with increasing pressure up to P1 ≈ 0.7 GPa, then an unexpected suppression on superconductivity happens until pressure around 1.1 GPa, after that,
T
c
is enhanced with increasing pressure again. The CDW is completely suppressed at a critical pressure P2 ≈ 2 GPa together with a maximum
T
c
of about 8 K. In contrast to a common dome-like behavior, the pressure-dependent
T
c
shows an unexpected double-peak behavior. The unusual suppression of
T
c
at P1 is concomitant with the rapidly damping of quantum oscillations, sudden enhancement of the residual resistivity and rapid decrease of magnetoresistance. Our discoveries indicate an unusual competition between superconductivity and CDW state in pressurized kagome lattice.
The recently discovered kagome metal
A
V
3
Sb
5
is a new playground to study the interplay between superconductivity and charge-density-wave (CDW) state. Here, the authors report pressure-dependent evolution of CDW and superconductivity in CsV
3
Sb
5
, suggesting an unusual competition between the two phases.
Journal Article