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Cold atoms with laser-induced spin-orbit (SO) interactions provide a platform to explore quantum physics beyond natural conditions of solids. Here we propose and experimentally realize two-dimensional (2D) SO coupling and topological bands for a rubidium-87 degenerate gas through an optical Raman lattice, without phase-locking or fine-tuning of optical potentials. A controllable crossover between 2D and 1D SO couplings is studied, and the SO effects and nontrivial band topology are observed by measuring the atomic cloud distribution and spin texture in momentum space. Our realization of 2D SO coupling with advantages of small heating and topological stability opens a broad avenue in cold atoms to study exotic quantum phases, including topological superfluids.

The concept of non-Hermiticity has expanded the understanding of band topology, leading to the emergence of counter-intuitive phenomena. An example is the non-Hermitian skin effect (NHSE) 1 , 2 , 3 , 4 , 5 , 6 – 7 , which involves the concentration of eigenstates at the boundary. However, despite the potential insights that can be gained from high-dimensional non-Hermitian quantum systems in areas such as curved space 8 , 9 – 10 , high-order topological phases 11 , 12 and black holes 13 , 14 , the realization of this effect in high dimensions remains unexplored. Here we create a two-dimensional (2D) non-Hermitian topological band for ultracold fermions in spin–orbit-coupled optical lattices with tunable dissipation, which exhibits the NHSE. We first experimentally demonstrate pronounced nonzero spectral winding numbers in the complex energy plane with nonzero dissipation, which establishes the existence of 2D skin effect. Furthermore, we observe the real-space dynamical signature of NHSE in real space by monitoring the centre of mass motion of atoms. Finally, we also demonstrate that a pair of exceptional points are created in the momentum space, connected by an open-ended bulk Fermi arc, in contrast to closed loops found in Hermitian systems. The associated exceptional points emerge and shift with increasing dissipation, leading to the formation of the Fermi arc. Our work sets the stage for further investigation into simulating non-Hermitian physics in high dimensions and paves the way for understanding the interplay of quantum statistics with NHSE. A two-dimensional non-Hermitian topological band is created in an ultracold system of fermions, which exhibits the non-Hermitian skin effect.

The observation of topological phases beyond two dimensions, as widely reported in solid-state systems1,2, has been an open challenge for ultracold atoms. Although many theoretical schemes have been proposed, the experimental complexity in realizing and characterizing the three-dimensional (3D) band structure has acted as a barrier against experiments achieving this. Here, we realize a 3D spin–orbit coupled nodal-line semimetal in an optical Raman lattice filled with ultracold fermions, and observe the bulk line nodes in the band structure. The realized topological semimetal exhibits an emergent magnetic group symmetry. This allows detection of the nodal lines by effectively reconstructing the 3D topological band from a series of measurements of integrated spin textures, which precisely render spin textures on the parameter-tuned magnetic-group-symmetric planes. The detection technique can be applied generally to explore 3D topological states of similar symmetries. Furthermore, we observe the band inversion lines from topological quench dynamics, which are bulk counterparts of Fermi arc states and connect the Dirac points, reconfirming the realized topological band. Our results demonstrate an approach to effectively observe 3D band topology, and open the way to probe exotic topological physics for ultracold atoms in high dimensions.

A fractal material exhibits self-similarity at different length scales across the system size. Theorists now show that an interacting one-dimensional quasiperiodic material can host a multifractal charge-density-wave phase.

Point contact spectroscopy measurements show a superconducting phase around the point contact region on the surface of the 3D Dirac semimetal Cd 3 As 2 . Three-dimensional (3D) Dirac semimetals, which possess 3D linear dispersion in the electronic structure as a bulk analogue of graphene, have lately generated widespread interest in both materials science and condensed matter physics 1 , 2 . Recently, crystalline Cd 3 As 2 has been proposed and proved to be a 3D Dirac semimetal that can survive in the atmosphere 3 , 4 , 5 , 6 , 7 , 8 , 9 . Here, by using point contact spectroscopy measurements, we observe exotic superconductivity around the point contact region on the surface of Cd 3 As 2 crystals. The zero-bias conductance peak (ZBCP) and double conductance peaks (DCPs) symmetric around zero bias suggest p -wave-like unconventional superconductivity. Considering the topological properties of 3D Dirac semimetals, our findings may indicate that Cd 3 As 2 crystals under certain conditions could be topological superconductors 10 , 11 , 12 , 13 , which are predicted to support Majorana zero modes or gapless Majorana edge/surface modes in the boundary depending on the dimensionality of the material 14 , 15 , 16 , 17 .

In recent years, biomarkers have been integrated into the diagnostic process and have become increasingly indispensable for obtaining knowledge of the neurodegenerative processes in Alzheimer’s disease (AD). Peripheral blood mononuclear cells (PBMCs) in human blood have been reported to participate in a variety of neurodegenerative activities. Here, a single-cell RNA sequencing analysis of PBMCs from 4 AD patients (2 in the early stage, 2 in the late stage) and 2 normal controls was performed to explore the differential cell subpopulations in PBMCs of AD patients. A significant decrease in B cells was detected in the blood of AD patients. Furthermore, we further examined PBMCs from 43 AD patients and 41 normal subjects by fluorescence activated cell sorting (FACS), and combined with correlation analysis, we found that the reduction in B cells was closely correlated with the patients’ Clinical Dementia Rating (CDR) scores. To confirm the role of B cells in AD progression, functional experiments were performed in early-stage AD mice in which fibrous plaques were beginning to appear; the results demonstrated that B cell depletion in the early stage of AD markedly accelerated and aggravated cognitive dysfunction and augmented the Aβ burden in AD mice. Importantly, the experiments revealed 18 genes that were specifically upregulated and 7 genes that were specifically downregulated in B cells as the disease progressed, and several of these genes exhibited close correlation with AD. These findings identified possible B cell-based AD severity, which are anticipated to be conducive to the clinical identification of AD progression. Alzheimer’s disease: A new biomarker for disease progression? Molecular tests built around analyzing B cells, a specialized type of immune cell, could aid in the diagnosis of Alzheimer’s disease. Liu-Lin Xiong from the Affiliated Hospital of Zunyi Medical University, China, and coworkers used single-cell RNA sequencing to profile gene activity in individual peripheral blood mononuclear cells from people with and without Alzheimer’s disease. They discovered that people with Alzheimer’s, especially those with more advanced disease, had lower levels of circulating B cells than healthy subjects. Twenty-five specific genes in the B cells were expressed at significantly higher or lower levels as the disease progressed. The researchers found similar results regarding B cells and Alzheimer’s progression in mouse models, and showed that massive depletion of B cells in the early onset was associated with accelerated cognitive decline and increased accumulation of sticky brain plaques.

Near-infrared luminophores have many advantages in advanced applications, especially for structures without π-conjugation aromatic rings. However, the fabrication of red clusteroluminogens from nonconjugated polymers is still a big challenge, let alone the near-infrared clusteroluminogens. Here, we develop nonconjugated luminophores with full-spectrum from blue to near-infrared light (470 ~ 780 nm), based on color phenomenon of nonconjugated polyesters synthesized from the amine-initiated copolymerization of epoxides and cyclic anhydrides. We reveal that amines act as initiators attached to polymer chain ends. The formation of various amine-ester complexes in polyesters induces red to near-infrared light, conceptually, amine-ester complexed clusteroluminescence via intra/inter-chain charge transfer. Significantly, emission colors can be easily tuned by the contents and types of amines, microstructures of polyesters, and their concentration. This work provides a low-cost, scalable platform and strategy for the production of high-efficiency, multicolor luminescent materials. Near-infrared luminescence is useful for advance applications, but is challenging to achieve through clusteroluminescence. Here, the authors report the use of amine-initiated polyesters for amine-ester clusters with near-infrared emission.

Transition metal hydroxides have attracted a lot of attention as the electrode materials for supercapacitors owing to their relatively high theoretical capacity, low cost, and facile preparation methods. However, their low intrinsic conductivity deteriorates their high-rate performance and cycling stability. Here, self-supported sheets-on-wire CuO@Ni(OH)2/Zn(OH)2 (CuO@NiZn) composite nanowire arrays were successfully grown on copper foam. The CuO nanowire backbone provided enhanced structural stability and a highly efficient electron-conducting pathway from the active hydroxide nanosheets to the current collector. The resulting CuO@NiZn as the battery-type electrode for supercapacitor application delivered a high capacity of 306.2 mAh g−1 at a current density of 0.8 A g−1 and a very stable capacity of 195.1 mAh g−1 at 4 A g−1 for 10,000 charge–discharge cycles. Furthermore, a quasi-solid-state hybrid supercapacitor (qss HSC) was assembled with active carbon, exhibiting 125.3 mAh g−1 at 0.8 A g−1 and a capacity of 41.6 mAh g−1 at 4 A g−1 for 5000 charge–discharge cycles. Furthermore, the qss HSC was able to deliver a high energy density of about 116.0 Wh kg−1. Even at the highest power density of 7.8 kW kg−1, an energy density of 20.5 Wh kg−1 could still be obtained. Finally, 14 red light-emitting diodes were lit up by a single qss HSC at different bending states, showing good potential for flexible energy storage applications.

The characterization of corn starch (CS) films impregnated with CaCO3 nanoparticles was investigated. Criteria such as morphology, crystallinity, water vapor permeability (WVP), opacity, and mechanical properties were the focus of the investigation. It was found that the CaCO3 contents had significant effects on the tensile properties of the nanocomposite films. The addition of CaCO3 nanoparticles to the CS films significantly increased tensile strength from 1.40 to 2.24 MPa, elongation from 79.21 to 118.98%, and Young's modulus from 1.82 to 2.41 MPa. The incorporation of CaCO3 nanoparticles increased the opacity of films, lowered the degree of WVP and film solubility value compared to those of the CS films. The results of scanning electron microscopy (SEM) showed that with the increase of CaCO3 nanoparticles content in starch films, the roughness of the films increased, and pores or cavities were found on the surface of the films, while small cracks were observed in the structures of the fractured surfaces. X-ray diffraction showed that the addition of nanoparticles increased the peaks in the intensity of films.

The polar surface and hydrophilicity of starch nanoparticles (SNPs) result in their poor dispersibility in nonpolar solvent and poor compatibility with hydrophobic polymers, which limited the application in hydrophobic system. To improve their hydrophobicity, SNPs prepared through self-assembly of short chain amylose debranched from cooked taro starch, were modified by octenyl succinic anhydride (OSA). Size via dynamic light scattering of OSA-SNPs increased compared with SNPs. Fourier transform infrared spectroscopy data indicated the OSA-SNPs had a new absorption peak at 1727 cm-1, which was the characteristic peak of carbonyl, indicating the formation of the ester bond. The dispersibility of the modified SNPs in the mixture of water with nonpolar solvent increased with increasing of degree of substitution (DS). OSA-SNPs appear to be a potential agent to stabilize the oil-water systems.