Catalogue Search | MBRL
Are you sure you want to remove the book from the shelf?
{{itemTitle}}
328
result(s) for
"Lowe, Jason"
Sort by:
Concepts and Terminology for Sea Level: Mean, Variability and Change, Both Local and Global
Changes in sea level lead to some of the most severe impacts of anthropogenic climate change. Consequently, they are a subject of great interest in both scientific research and public policy.This paper defines concepts and terminology associated with sea level and sea-level changes in order to facilitate progress in sea-level science, in which communication is sometimes hindered by inconsistent and unclear language.We identify key terms and clarify their physical and mathematical meanings, make links between concepts and across disciplines, draw distinctions where there is ambiguity, and propose new terminology where it is lacking or where existing terminology is confusing. We include formulae and diagrams to support the definitions.
Journal Article
Crazy water, pickled lemons : enchanting dishes from the Middle East, Mediterranean and North Africa
\"A new edition of the original gem at the heart of celebrated food writer Diana Henry's much-loved repertoire\" -- Back cover.
BOOK
Future changes to high impact weather in the UK
High impact weather events such as extreme temperatures or rainfall can cause significant disruption across the UK affecting sectors such as health, transport, agriculture and energy. In this study we draw on the latest set of UK climate projections, UKCP, to examine metrics relating to high-impact weather over the UK and how these change with different levels of future global warming from 1.5 °C to 4 °C above pre-industrial. The changes to these hazards show increases in the frequency of extremely hot days and nights, with a UK average increase in hot days of between 5 and 39 days per year between 1.5 °C and 4 °C of global warming. Projections indicate an increase in cooling degree days of 134–627% and an increase in growing degree days of 19–60% between 1.5 °C and 4 °C of global warming. Extremely hot nights, which are currently rare, are emerging as more common occurrences. The frequency of high daily temperatures and rainfall increase systematically, while the frequency of very cold conditions (based on days where temperatures fall below 0 °C) is shown to decrease by 10 to 49 days per year. A reduction in heating degree days, of 11–32% between 1.5 °C and 4 °C of warming, is projected. Levels of daily rainfall, which currently relate to increased risk of river flooding, are shown to increase across the country, with increases of days with high impact levels of rainfall occurring by 1 to 8 days per year between 1.5 °C and 4 °C of warming. Average drought severity is projected to increase for 3-, 6-, 12- and 36-month-long droughts. The largest changes in the severity of the 12-month drought are between −3 and +19% between 1.5 °C and 4 °C of warming and for 36-month drought between −2 and +54% between 1.5 °C and 4 °C of warming. The projected future changes in high impact weather from this study will enable the characterization of climate risks and ultimately be able to better inform adaptation planning in different sectors to support the increase in resilience of the UK to future climate variability and change.
Journal Article
Network programmability and automation : skills for the next-generation network engineer
\"This practical guide shows network engineers how to use a range of technologies and tools--including Linux, Python, JSON, and XML--to automate their systems through code. [This book] will help you simplify tasks involved in configuring, managing, and operating network equipment, topologies, services, and connectivity.\"--Page 4 of cover.
Book
High sensitivity of tropical precipitation to local sea surface temperature
Precipitation and atmospheric circulation are the coupled processes through which tropical ocean surface temperatures drive global weather and climate
1
–
5
. Local sea surface warming tends to increase precipitation, but this local control is difficult to disentangle from remote effects of conditions elsewhere. As an example of such a remote effect, El Niño Southern Oscillation (ENSO) events in the equatorial Pacific Ocean alter precipitation across the tropics. Atmospheric circulations associated with tropical precipitation are predominantly deep, extending up to the tropopause. Shallow atmospheric circulations
6
–
8
affecting the lower troposphere also occur, but the importance of their interaction with precipitation is unclear. Uncertainty in precipitation observations
9
,
10
and limited observations of shallow circulations
11
further obstruct our understanding of the ocean’s influence on weather and climate. Despite decades of research, persistent biases remain in many numerical model simulations
12
–
18
, including excessively wide tropical rainbands
14
,
18
, the ‘double-intertropical convergence zone problem’
12
,
16
,
17
and too-weak responses to ENSO
15
. These biases demonstrate gaps in our understanding, reducing confidence in forecasts and projections. Here we use observations to show that seasonal tropical precipitation has a high sensitivity to local sea surface temperature. Our best observational estimate is an 80 per cent change in precipitation for every gram per kilogram change in the saturation specific humidity (itself a function of the sea surface temperature). This observed sensitivity is higher than in 43 of the 47 climate models studied, and is associated with strong shallow circulations. Models with more realistic (closer to 80%) sensitivity have smaller biases across a wide range of metrics. Our results apply to both temporal and spatial variation, over regions where climatological precipitation is about one millimetre per day or more. Our analyses of multiple independent observations, physical constraints and model data underpin these findings. The spread in model behaviour is further linked to differences in shallow convection, thus providing a focus for accelerated research to improve seasonal forecasts through multidecadal climate projections.
The response of tropical precipitation to variation in sea surface temperature is stronger than in most climate models, with cool and warm ocean regions linked by strong shallow atmospheric circulations.
Journal Article
The impact of Earth system feedbacks on carbon budgets and climate response
A number of studies have examined the size of the allowable global cumulative carbon budget compatible with limiting twenty-first century global average temperature rise to below 2°C and below 1.5°C relative to pre-industrial levels. These estimates of cumulative emissions have a number of uncertainties including those associated with the climate sensitivity and the global carbon cycle. Although the IPCC fifth assessment report contained information on a range of Earth system feedbacks, such as carbon released by thawing of permafrost or methane production by wetlands as a result of climate change, the impact of many of these Earth system processes on the allowable carbon budgets remains to be quantified. Here, we make initial estimates to show that the combined impact from typically unrepresented Earth system processes may be important for the achievability of limiting warming to 1.5°C or 2°C above pre-industrial levels. The size of the effects range up to around a 350 GtCO2 budget reduction for a 1.5°C warming limit and around a 500 GtCO2 reduction for achieving a warming limit of 2°C. Median estimates for the extra Earth system forcing lead to around 100 GtCO2 and 150 GtCO2, respectively, for the two warming limits. Our estimates are equivalent to several years of anthropogenic carbon dioxide emissions at present rates. In addition to the likely reduction of the allowable global carbon budgets, the extra feedbacks also bring forward the date at which a given warming threshold is likely to be exceeded for a particular emission pathway.
This article is part of the theme issue 'The Paris Agreement: understanding the physical and social challenges for a warming world of 1.5°C above pre-industrial levels'.
Journal Article
Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A–SF3b complex
Pladienolide, herboxidiene and spliceostatin have been identified as splicing modulators that target SF3B1 in the SF3b subcomplex. Here we report that PHF5A, another component of this subcomplex, is also targeted by these compounds. Mutations in PHF5A-Y36, SF3B1-K1071, SF3B1-R1074 and SF3B1-V1078 confer resistance to these modulators, suggesting a common interaction site. RNA-seq analysis reveals that PHF5A-Y36C has minimal effect on basal splicing but inhibits the global action of splicing modulators. Moreover, PHF5A-Y36C alters splicing modulator-induced intron-retention/exon-skipping profile, which correlates with the differential GC content between adjacent introns and exons. We determine the crystal structure of human PHF5A demonstrating that Y36 is located on a highly conserved surface. Analysis of the cryo-EM spliceosome B
act
complex shows that the resistance mutations cluster in a pocket surrounding the branch point adenosine, suggesting a competitive mode of action. Collectively, we propose that PHF5A–SF3B1 forms a central node for binding to these splicing modulators.
A number of natural occurring small-molecule splicing modulators are known. Here, the authors combine chemogenomic, structural and biochemical methods and show that these compounds also target the spliceosome-associated protein PHF5A and propose a potential modulator binding site in the PHF5A–SF3B1 complex.
Journal Article
The Scenario Model Intercomparison Project (ScenarioMIP) for CMIP6
Projections of future climate change play a fundamental role in improving understanding of the climate system as well as characterizing societal risks and response options. The Scenario Model Intercomparison Project (ScenarioMIP) is the primary activity within Phase 6 of the Coupled Model Intercomparison Project (CMIP6) that will provide multi-model climate projections based on alternative scenarios of future emissions and land use changes produced with integrated assessment models. In this paper, we describe ScenarioMIP's objectives, experimental design, and its relation to other activities within CMIP6. The ScenarioMIP design is one component of a larger scenario process that aims to facilitate a wide range of integrated studies across the climate science, integrated assessment modeling, and impacts, adaptation, and vulnerability communities, and will form an important part of the evidence base in the forthcoming Intergovernmental Panel on Climate Change (IPCC) assessments. At the same time, it will provide the basis for investigating a number of targeted science and policy questions that are especially relevant to scenario-based analysis, including the role of specific forcings such as land use and aerosols, the effect of a peak and decline in forcing, the consequences of scenarios that limit warming to below 2°C, the relative contributions to uncertainty from scenarios, climate models, and internal variability, and long-term climate system outcomes beyond the 21st century. To serve this wide range of scientific communities and address these questions, a design has been identified consisting of eight alternative 21st century scenarios plus one large initial condition ensemble and a set of long-term extensions, divided into two tiers defined by relative priority. Some of these scenarios will also provide a basis for variants planned to be run in other CMIP6-Endorsed MIPs to investigate questions related to specific forcings. Harmonized, spatially explicit emissions and land use scenarios generated with integrated assessment models will be provided to participating climate modeling groups by late 2016, with the climate model simulations run within the 2017-2018 time frame, and output from the climate model projections made available and analyses performed over the 2018-2020 period.
Journal Article