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57 result(s) for "MULQUEEN, MICHAEL"
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Re-evaluating Irish national security policy
On the afternoon of September 11 2001 the Irish Prime Minister (Taoiseach), Bertie Ahern ordered the ‘heads of the security services of key government departments’ to undertake a complete re-evaluation of measures to protect the state from attack. Hence, underway within hours of the 9/11 outrage in the United States was potentially the most far-reaching review of Irish national security in decades. This book, the first major academic investigation of Irish national security policy as it has operated since 9/11, provides a theoretically informed analysis of that re-evaluation and the decisions which have been taken as a consequence of it up until September 2008. In so doing it draws on unprecedented access to Ireland’s police, security and intelligence agencies; over twenty senior personnel agreed to be interviewed.Theoretically the author demonstrates the utility to the analysis of national security policy of three conceptual models of historical institutionalism, governmental politics and threat evaluation. The text is of interest to scholars of Security Studies, International Relations and Politics, as well as state and NGO personnel, journalists and general readers.
Re-evaluating Irish national security policy
The first major academic investigation of Irish national security policy as it has operated since 9/11. It draws on unprecedented access to Ireland's security and intelligence agencies; over twenty senior personnel were interviewed.
The Role of Endogenous Interleukin-12 in Resistance to Murine Cytomegalovirus (MCMV) Infection and a Novel Action for Endogenous IL-12 p40
Biologically active interleukin-12 (IL-12), comprising a 40 kDa subunit (p40) covalently linked to a 35 kDa subunit (p35), is produced in response to a range of infectious stimuli. Here, we demonstrate that mice deficient in either IL-12 p40 (p40-/-) or IL-12 p35 (p35-/-) are susceptible to murine cytomegalovirus (MCMV) infection in terms of survival (Balb/c p35-/-) and viral clearance (Balb/c p35-/- and Balb/c p40-/-), and this susceptibility may be correlated to a deficiency in serum interferon-γ (IFN-γ) levels. These data support a role for endogenous IL-12 in controlling MCMV infection. The IL-12 p40 subunit is produced in excess of IL-12 p35, and to date the function of the excess endogenous p40 has been assumed to be one of IL-12 antagonism, as demonstrated by experiments with exogenous p40 both in vivo and in vitro. We show that Balb/c p35-/- alone are significantly compromised in survival of a sublethal infection and in clearance of virus from the spleen. These mice produce a very early IFN-γ spike (8 h after infection) and an aberrant tumor necrosis factor-α (TNF-α) spike (day 2 after infection). MCMV infection has revealed an altered Balb/c p35-/- phenotype compared with Balb/c p40-/-, and this indicates that endogenous p40 may have an activity independent of and additional to IL-12 antagonism in vivo.
Political and financial pressures on national security
The previous chapter summarised the Irish national security apparatus, considered the State’s responses to threats during the Emergency and during the Troubles and drew some comparisons between Ireland’s frontline agencies and those of other states. Attention focuses now on the literature of Irish national security policy. This review will be divided into three sections to reflect what appear to be central empirical concerns of the authors. These are firstly, political pressure on the Garda Síochána; secondly, financial pressure on the Defence Forces; and thirdly, Anglo-Irish considerations in Irish national security policy. The objective is to situate the study in the
Decision-makers under pressure
So far, this study has examined Irish policy over a timeline stretching over the seven years after 9/11. Now, the focus narrows to the period immediately after the attack, during which Irish security policy underwent rapid review and all the main aspects of current policy were put in place (e.g. the decision to emphasise emergency planning as the primary concern). The dates in question are between September 11 and approximately October 3 2001. On the afternoon of September 11 the Taoiseach, Bertie Ahern, and the Tánaiste, Mary Harney, convened a meeting of the ‘heads of the security services of key