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Diagnostic value and key features of computed tomography in Coronavirus Disease 2019
On 31 December 2019, a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, Hubei province, China, and caused the outbreak of the Coronavirus Disease 2019 (COVID-19). To date, computed tomography (CT) findings have been recommended as major evidence for the clinical diagnosis of COVID-19 in Hubei, China. This review focuses on the imaging characteristics and changes throughout the disease course in patients with COVID-19 in order to provide some help for clinicians. Typical CT findings included bilateral ground-glass opacity, pulmonary consolidation, and prominent distribution in the posterior and peripheral parts of the lungs. This review also provides a comparison between COVID-19 and other diseases that have similar CT findings. Since most patients with COVID-19 infection share typical imaging features, radiological examinations have an irreplaceable role in screening, diagnosis and monitoring treatment effects in clinical practice.
Journal Article
التخفيف من حدة الفقر في الصين المعاصرة
استنادا إلى نظرة عامة على أوضاع الفقر، يقدم هذا الكتاب مسار التخفيف من حدة الفقر والتنمية في الصين، ويشرح نموذج التنمية والتخفي من حدة الفقر بخصائص صينية والتمسك بمباديء (سيطرة الحكومة ومشاركة المجتمع والاعتماد على الذات والتنمية الموجهة والتنمية الشاملة) كما يقدم الكتاب تلخيصا شاملا لإنجازات الصين العظيمة وخبراتها الهامة وإسهاماتها الرئيسية في قضية التخفيف من حدة الفقر في العالم، ويعرض بإيجاز نظرات وممارسات التخفيف المستهدف من الفقر في العصر الجديد من أجل توفير مراجع لكسب المعركة ضد الفقر في الصين وقضية التخفيف من حدة الفقر في العالم.
Book
Multi-Scale Surface Treatments of Titanium Implants for Rapid Osseointegration: A Review
The propose of this review was to summarize the advances in multi-scale surface technology of titanium implants to accelerate the osseointegration process. The several multi-scaled methods used for improving wettability, roughness, and bioactivity of implant surfaces are reviewed. In addition, macro-scale methods (e.g., 3D printing (3DP) and laser surface texturing (LST)), micro-scale (e.g., grit-blasting, acid-etching, and Sand-blasted, Large-grit, and Acid-etching (SLA)) and nano-scale methods (e.g., plasma-spraying and anodization) are also discussed, and these surfaces are known to have favorable properties in clinical applications. Functionalized coatings with organic and non-organic loadings suggest good prospects for the future of modern biotechnology. Nevertheless, because of high cost and low clinical validation, these partial coatings have not been commercially available so far. A large number of in vitro and in vivo investigations are necessary in order to obtain in-depth exploration about the efficiency of functional implant surfaces. The prospective titanium implants should possess the optimum chemistry, bionic characteristics, and standardized modern topographies to achieve rapid osseointegration.
Journal Article
Water cycle management : a new paradigm of wastewater reuse and safety control
This book focuses on environmental engineering, and on wastewater treatment and reuse in particular, which is a vital aspect for countries and regions suffering from water shortages. It introduces a new water cycle management concept for designing water systems that mimic the hydrological cycle, where reclaimed water is produced, stored/regulated, supplied and used in a semi-natural manner so that its self-purification capacity and system efficiency can be maximized. To ensure safe water throughout the cycle, emphasis is placed on the control of ecological and pathogenic risks using a series of quality indices associated with bioassays and molecular biological analyses, as well as risk assessments focusing on protecting the environment and human health. Together with theoretical and technological discussions, a real case of a district water system for maximizing water circulation and reuse by means of a sophisticated water cycle is presented. This book introduces readers to essential new concepts and practices and illustrates the future perspectives offered by a new paradigm for design and safety control in the context of wastewater reuse systems.
Book
Resistance of steppe communities to extreme drought in northeast China
Background and Aims
Declaring the drought-resistance of plant communities in grassland and the underlying mechanisms is crucial under climatic change scenario. Here we aimed to quantify aboveground & belowground net primary productivity (ANPP & BNPP) and their allocation in response to extreme droughts, and to uncover any underlying factors of drought resistance.
Methods
We experimentally reduced growing season rainfall by 66% for four years in two grassland sites (Sandy and Loamy site respectively), and measured ANPP and BNPP yearly and evaluated the relatedness of drought-induced changes for them to plant traits (Plant height, δ
13
C, SLA and LNC) and community composition.
Results
Experimental drought decreased species richness, ANPP of forbs and the total at both sites, but decreased ANPP of grasses only at the Sandy site. Experimental drought has non-significant effect on total BNPP at both sites, but increased 10–20 cm BNPP and decreased 0–10 cm BNPP. BNPP ratio was kept unchanged at the Loamy site but increased at the Sandy site. Moreover, the communities at the Loamy site showed lower δ
13
C, SLA and LNC, but greater height.
Conclusions
Our study demonstrates that extreme drought can impact community productivity and structure, and highlights the importance of plant traits, community composition and soil properties in modulating the responses and resistance of steppe communities to extreme drought.
Journal Article
Myeloid-derived suppressor cells—new and exciting players in lung cancer
Lung cancer (LC) is the leading cause of cancer-related death worldwide due to its late diagnosis and poor outcomes. As has been found for other types of tumors, there is increasing evidence that myeloid-derived suppressor cells (MDSCs) play important roles in the promotion and progression of LC. Here, we briefly introduce the definition of MDSCs and their immunosuppressive functions. We next specifically discuss the multiple roles of MDSCs in the lung tumor microenvironment, including those in tumor growth and progression mediated by inhibiting antitumor immunity, and the associations of MDSCs with a poor prognosis and increased resistance to chemotherapy and immunotherapy. Finally, we also discuss preclinical and clinical treatment strategies targeting MDSCs, which may have the potential to enhance the efficacy of immunotherapy.
Journal Article
Community response of arbuscular mycorrhizal fungi to extreme drought in a cold-temperate grassland
• Climate extremes pose enormous threats to natural ecosystems. Arbuscular mycorrhizal (AM) fungi are key plant symbionts that can affect plant community dynamics and ecosystem stability. However, knowledge about how AM fungal communities respond to climate extremes in natural ecosystems remains elusive.
• Based on a grassland extreme drought experiment in Inner Mongolia, we investigated the response of AM fungal communities to extreme drought in association with plant communities. The experiment simulated two types of extreme drought (chronic/intense) of once-in-20-year occurrence.
• AM fungal richness and community composition exhibited high sensitivity to extreme drought and were more sensitive to intense drought than chronic drought. This community sensitivity (i.e. decline in richness and shifts in community composition) of AM fungi can be jointly explained by soil moisture, plant richness, and aboveground productivity. Notably, the robustness of the plant–AM fungal community co-response increased with drought intensity.
• Our results indicate that AM fungal communities are sensitive to climate extremes, and we propose that the plant community mediates AM fungal community responses. Given the ubiquitous nature of AM associations, their climate sensitivity may have profound consequences on plant communities and ecosystem stability under climate change.
Journal Article