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In November 2021, the Royal Meteorological Society Data Assimilation (DA) Special Interest Group and the University of Reading hosted a virtual meeting on the topic of DA for convection‐permitting numerical weather prediction. The goal of the meeting was to discuss recent developments and review the challenges including methodological developments and progress in making the best use of observations. The meeting took place over two half days on the 10 and 12 November, and consisted of six talks and a panel discussion. The scientific presentations highlighted some recent work from Europe and the USA on convection‐permitting DA including novel developments in the assimilation of observations such as cloud‐affected satellite radiances in visible channels, ground‐based profiling networks, aircraft data, and radar reflectivity data, as well as methodological advancements in background and observation error covariance modelling and progress in operational systems. The panel discussion focused on key future challenges including the handling of multiscales (synoptic‐, meso‐, and convective‐scales), ensemble design, the specification of background and observation error covariances, and better use of observations. These will be critical issues to address in order to improve short‐range forecasts and nowcasts of hazardous weather. We report on a meeting on progress and challenges in convection‐permitting data assimilation. Novel developments include the assimilation of novel observations such as cloud‐affected satellite radiances, ground‐based profiling networks and aircraft data, as well as methodological advancements in error covariance modelling, and progress in operational systems. Key future challenges include the handling of multiple scales, the design of ensembles and observation networks: these will be critical issues for short‐range forecasts and nowcasts of hazardous weather.

Crowd‐sourced observations (CSO) offer great potential for numerical weather prediction (NWP). This paper offers a synthesis of progress, challenges and opportunities in this area based on a special session of the EWGLAM Meeting in 2019, concentrating on high‐resolution limited‐area models (LAMs). Two main application areas of CSO are described: data assimilation and verification. One part of data assimilation developments concentrates on smartphone pressure observations, which represent a large volume of data. However, special care has to be taken about data protection and the quality of observations. In this paper, two examples are presented: the SMAPS experiment from Denmark and the uWx experiment from the United States. Another data assimilation topic is citizen observations with low‐cost weather sensors; here an example from Norway is presented using Netatmo stations. The other application area is the use of CSO for model verification. One novel method developed in the United Kingdom is applying social media data to detect severe weather events. This approach is especially important because one future application area of LAM NWP models is impact‐oriented warnings. Crowd‐sourced observations (CSO) offer great potential for numerical weather prediction (NWP). This paper offers a synthesis of progress, challenges and opportunities in this area based on a special session of the EWGLAM Meeting in 2019, concentrating on high‐resolution limited‐area models (LAMs). Two main application areas of CSO are described: data assimilation and verification. Using citizen observations to improve operational weather forecasts. Noncorrected forecast of temperature (left) and analysed (corrected) field (right). Coloured circles are the observations (in °C)

Nonprofit organizations, including nonprofit hospitals, have been exempt from federal income taxation since their inception in the early 20th century, when these organizations accounted for a small portion of the US economy. Nearly all hospitals were organized as nonprofit at that time, affiliated with either religious groups or foundations, and they served families who could not afford to pay a doctor to visit their home. Providing public benefits without question, these hospitals depended heavily on charitable gifts to finance their operations and earned little, if any, net income. Over the ensuing 100 years, drastic changes in medical technology have transformed hospitals from places where the poor seek primary care and comfort to places where everyone goes to get various types of care when needed. Today, some nonprofit hospitals have expanded their roles further by undertaking programs to promote healthy lifestyles or otherwise prevent illness.

Cefotetan disodium–induced hemolytic anemia has been reported previously, and some of these cases have been severe or fatal. We describe a case of severe hemolytic anemia that occurred in an 80-year-old woman who received cefotetan prophylactically after surgery for a small bowel obstruction. Eight days after the first dose of cefotetan, the patient developed a severe Coomb test–positive hemolytic anemia. Using flow cytometry, we demonstrated cefotetan-specific antibodies in her posttreatment serum, which were detectable at a serum dilution up to 1:10 000. The patient received corticosteroid therapy and blood transfusions, with improvement of her hematologic parameters, but died 54 days after admission for respiratory failure. To our knowledge, this is the first use of flow cytometry for the detection of cefotetan-induced red blood cell antibodies. This technique offers a sensitive, rapid, objective method for detecting drug-induced antibodies.

[...]a clinical review, \"The impact of noise on patients' sleep and the effectiveness of noise reduction strategies in intensive care units,\" published in the journal Critical Care, reports that sleep deprivation during a hospital stay slows healing. DESIGN STRATEGIES In addition to the WHO guidelines, several in dustry organizations provide noise-related stan dards, including the Facility Guidelines Institute (FGI), American Society for Health Care Engi neering (ASHE), American National Standards Institute /Acoustical Society of America (ANSI/ ASA), U.S. Green Building Council's LEED pro gram, and even the Veterans Administration. A study \"Effect of Noise in the Emergency Department on Occupational Burnout and Resignation Intention of Medical Staff,\" published in Noise & Health, found that long shifts in noisy environments can also raise staff stress, cause burnout, and reduce job satisfaction. High-performance window systems that meet the FGT's minimum STC 40 rating for sound proofing, strategic building orientation to minimize patient exposure to primary noise sources, and landscape design that includes natural sound barriers are viable design solutions.

* Cefotetan disodium-induced hemolytic anemia has been reported previously, and some of these cases have been severe or fatal. We describe a case of severe hemolytic anemia that occurred in an 80-year-old woman who received cefotetan prophylactically after surgery for a small bowel obstruction. Eight days after the first dose of cefotetan, the patient developed a severe Coomb test-positive hemolytic anemia. Using flow cytometry, we demonstrated cefotetan-specific antibodies in her posttreatment serum, which were detectable at a serum dilution up to 1:10 000. The patient received corticosteroid therapy and blood transfusions, with improvement of her hematologic parameters, but died 54 days after admission for respiratory failure. To our knowledge, this is the first use of flow cytometry for the detection of cefotetan-induced red blood cell antibodies. This technique offers a sensitive, rapid, objective method for detecting drug-induced antibodies. (Arch Patrol Lab Med. 2000;124:1344-1346)