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Louhajang River, Bangladesh, which crosses Tangail as a densely industrialized and urbanized city, supplies water for different purposes. This study reports the levels of pH, electrical conductivity (EC), and some toxic heavy metals in 40 water samples collected during the summer and winter seasons from Louhajang River. The winter season reported higher levels of the examined parameters than the summer season with significant variation ( p < 0.05) for all parameters, with the exception of Cd. The metal contents were assessed against local and international standards for drinking, irrigation, and aquatic life purposes where different trends were observed. The heavy metal evaluation index and the ecological risk index reported low to moderate risks. The spatial distribution of metal contents assigned hot spots in some sites along the riverbed. The health risk assessment for three population categories, i.e., adult male, adult female, and children, was examined. Cr and Cd recorded hazard index > 1 in all cases, indicating possible non-cancer risk. The total carcinogenic risk values during both seasons were > 1.0 × 10 −6 , indicating possible cancer risk. The adopted collection of different approaches (comparison against standard levels of toxicants, statistical analysis, spatial distribution, and health risk assessment) successfully demonstrates a whole picture of the environmental status of Louhajang River, Bangladesh.

Heavy metal enrichment in road dust has resulted from intensive anthropogenic activity, particularly urbanization, industrial activities and traffic emission, posing a hazard to urban ecosystems and human health. To promote optimal road dust management in urban environments, it is necessary to assess the possible ecological and health impact of toxic elements in road dust. In a heavily populated megacity like Dhaka, Bangladesh, large-scale risk assessments of contamination in road dust with heavy metals are limited. The present study aims at presenting a concentration of twenty-five metals in road dust (Na, K, Cs, Rb, Mg, Ca, Sr, Ba, Al, Zn, Cd, Pb, As, Sb, Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zr and W) in Dhaka megacity. We used a critical source-based positive matrix factorization model, source-oriented potential ecological risks and health risks. Out of the studied metals, Na, Ca, Zn, Cd, Cu, Zr and W exceeded the shale value. About 73%, 48%, 29% and 32% of sampling sites showed a higher level of pollution based on PLI, NIPI, PER and NIRI, respectively. PMF model identified that Cd (85.3%), Cr (62.4%), Ni (58.2%), Zn (81.8%) and Mn (65.9%) in road dust were primarily attributed to traffic emission, fuel combustion, metal processing, transport sources and natural sources, respectively. Fuel combustion and metal processing posed considerable and high risks based on modified potential ecological risk and NIRI. Based on health hazards, traffic emission posed a high cancer risk in adult males (29%), whereas transport sources contributed to females (21%) and children (23%).

Heavy metals in soil are harmful to natural biodiversity and human health, and it is difficult to estimate the effects accurately. To reduce pollution and manage risk in coal-mining regions, it is essential to evaluate risks for heavy metals in soil. The present study reviews the levels of 21 metals (Nb, Zr, Ag, Ni, Na, K, Mg, Rb, Zn, Ca, Sr, As, Cr, Fe, Pb, Cd, Co, Hg, Cu, Mn and Ti) in soils around Barapukuria coal-mining vicinity, Bangladesh which were reported in literature. An integrated approach for risk assessments with the positive matrix factorization (PMF) model, source-oriented ecological and health hazards were applied for the study. The contents of Rb, Ca, Zn, Pb, As, Ti, Mn, Co, Ag, Zr, and Nb were 1.63, 1.10, 1.97, 14.12, 1.20, 3.13, 1.22, 3.05, 3.85, 5.48, and 7.21 times greater than shale value. About 37%, 67%, 12%, and 85% of sampling sites posed higher risks according to the modified contamination factor, Nemerow pollution index, Nemerow integrated risk index, and mean effect range median quotient, respectively. Five probable metal sources were computed, including industrial activities to coal mining (17%), agricultural activities (33%), atmospheric deposition (19%), traffic emission (16%), and natural sources (15%). Modified Nemerow integrated risk index reported that agricultural activities, industrial coal mining activities, and atmospheric deposition showed moderate risk. Health hazards revealed that cancer risk values computed by the PMF-HHR model with identified sources were higher than the standard value (1.0E−04) for children, adult male, and female. Agricultural activities showed higher cancer risks to adult male (39%) and children (32%) whereas traffic emission contributed to female (25%). These findings highlight the ecological and health issues connected to potential sources of metal contamination and provide useful information to policymakers on how to reduce such risks.

The present study quantified Ni, Cu, Cr, Pb, Cd, As, Zn, and Fe levels in road dust collected from a variety of sites in Tangail, Bangladesh. The goal of this study was to use a matrix factorization model to identify the specific origin of these components and to evaluate the ecological and health hazards associated with each potential origin. The inductively coupled plasma mass spectrometry was used to determine the concentrations of Cu, Ni, Cr, Pb, As, Zn, Cd, and Fe. The average concentrations of these elements were found to be 30.77 ± 8.80, 25.17 ± 6.78, 39.49 ± 12.53, 28.74 ± 7.84, 1.90 ± 0.79, 158.30 ± 28.25, 2.42 ± 0.69, and 18,185.53 ± 4215.61 mg/kg, respectively. Compared to the top continental crust, the mean values of Cu, Pb, Zn, and Cd were 1.09, 1.69, 2.36, and 26.88 times higher, respectively. According to the Nemerow integrated pollution index (NIPI), pollution load index (PLI), Nemerow integrated risk index (NIRI), and potential ecological risk (PER), 84%, 42%, 30%, and 16% of sampling areas, respectively, which possessed severe contamination. PMF model revealed that Cu (43%), Fe (69.3%), and Cd (69.2%) were mainly released from mixed sources, natural sources, and traffic emission, respectively. Traffic emission posed high and moderate risks for modified NIRI and potential ecological risks. The calculated PMF model-based health hazards indicated that the cancer risk value for traffic emission, natural, and mixed sources had been greater than (1.0E−04), indicating probable cancer risks and that traffic emission posed 38% risk to adult males where 37% for both adult females and children.

The construction industry is essential in the economic development of Bangladesh. Yet, it poses significant environmental and social challenges, necessitating a transition towards circular economy (CE) in achieving sustainability as a holistic approach. However, the effective implementation of CE principles faces significant challenges, particularly in the context of Bangladesh, associated with high population density and rapid urbanisation despite limited resources. Despite all the problems stated, this research investigates the barriers hindering the adoption of CE practices within the Bangladeshi construction industry (BCI). Utilising a semi-structured interview approach, perspectives were gathered from 20 engineers deeply involved in various sectors of the BCI. The thematic analysis of the interview transcripts yielded five themes of challenges, namely, economic and financial constraints, policy and regulatory challenges, skill and capacity deficiencies, sociocultural barriers and technical barriers. Theoretically, this research contributes to a comprehensive understanding of the complexities surrounding the implementation of CE strategies in emerging economies like Bangladesh. Practically, the findings would aid policymakers, researchers and industry stakeholders in developing, prioritising and implementing policies and strategies to facilitate the transition toward a circular construction industry. It also underscores some significant issues to consider in the pathway in achieving several Sustainable Development Goals (SDGs), especially SDG 9 (Industry, Innovation and Infrastructure), SDG 11 (Sustainable Cities and Communities) and SDG 12 (Responsible Production and Consumption).

Myelofibrosis (MF) is a rare disorder that is classified as one of the myeloproliferative disorders. It is a BCR-ABL1- negative myeloproliferative neoplasm characterized by abnormal proliferation of hemopoietic stem cells within the bone marrow, which leads to overproduction of fibrous tissue. Our patient a young girl of 17 year old presented with lump in left upper abdomen, shortness of breath & generalized swelling. The diagnosis was made based on severe anaemia, pancytopenia in peripheral blood film. Bone marrow trephine biopsy from the tibia revealed myelofibrosis. Splenectomy was done in an attempt to reduce the total volume of malignant cells and improve the features of hypersplenism. Myelofibrosis with hypersplenism in a 17- year- old girl is reported rarely. However, when it does, it usually runs rapid and fatal course. J Bangladesh Coll Phys Surg 2023; 41: 239-243

In the Sandha river of Bangladesh, we investigated the temporal and geographical fluctuation in species of fish composition and diversity. The extent of our understanding of the fish variety in this river varies greatly on both a temporal and a geographical scale. From July 2021 to June 2022, fish specimens were gathered from five stations using various conventional fishing methods. During the study period, 5118 individuals from 67 species were collected which include 8 orders, 24 families, and 54 genera. Cypriniformes made up the majority of the order (32.84%), whereas Beloniformes and Tetraodontiformes made up the least number of species (1.49% each). Six species were listed as endangered (8.96%), seven as vulnerable (10.45%), nine as near threatened (13.43%), forty-three as least concern (64.18%), one with data deficient (1.49%), and one as not evaluated (1.49%) in Bangladesh. In order to quantify the temporal and geographical changes in community composition, diversity indices were calculated and put to use. Three (temperature, humidity, and rainfall) out of the four environmental factors (temperature, humidity, rainfall, and photoperiod) had a big impact on how species were distributed. At a similarity level of 79% and 75.5% separation, 2 substantial clusters were seen in the case of stations and 2 large clusters were detected in the case of months, respectively. However, at a similarity threshold of 20% separation, three different groups of fish species were found. Our research offers the most recent status data on fish distribution in the Sandha river. The knowledge acquired from this research is crucial for creating protection and management plans that will promote the long-term viability of fishery resources in the Sandha river and its nearby coastal tributaries.

Metal(oid)s contamination in agricultural soils can create adverse environmental conditions and pose human health risks. The present study was conducted to assess metal(oid)s contents, source identification, and ecological and health risks due to metal(oid)s contamination in BISIC industrial region soils of Tangail district Bangladesh. The mean ± SD of chromium (Cr), nickel (Ni), copper (Cu), arsenic (As), cadmium (Cd), and lead (Pb) were 8.67 ± 8.27 mg/kg, 13.76 ± 18.13 mg/kg, 23.46 ± 23.62 mg/kg, 4.93 ± 2.87 mg/kg, 1.56 ± 1.70 mg/kg, and 16.63 ± 9.32 mg/kg, respectively. The positive matrix factorization model identified lead-acid battery sources (49.53%), industrial sources (33.66%), and agricultural practices (16.63%) as potential sources of studied metal(oid)s. Contamination factor value of Cd (1.65) in the study area soils showed moderate contamination, whereas Nemerow-integrated pollution index (1.95) indicated slightly soil pollution and potential ecological risk (179.67) showed considerable risks. The HI value for adult male, female, and children due to ingestion, inhalation, and dermal contact was higher than 1, assuming severe non-cancer health risks. Total cancer risk value of Cr (1.14E-02) Ni (7.24E-04), As (2.33E-03), and Cd (3.09E-04) for adult male; Cr (1.23E-02), Ni (7.81E-04), As (2.51E-03), and Cd (3.32E-04) for adult female, whereas Cr (5.32E-02), Ni (3.38E-03), As (1.09E-02), Cd (1.44E-03), and Pb (1.00E-04) for children were exceeded the highest acceptable limit (1.0E-04) indicating possible cancer risks. The present study will help environmental engineers and policymakers to control metal pollution in agricultural soils based on applicable and reasonable evaluation methods.

A middle aged man presented with fever for 14 days, dry cough for 10 days and shortness of breath for 6 days. He tested positive for RT-PCR for COVID-19 on 5th day of illness. Patient was maintaining home isolation until he developed shortness of breath. After hospitalization patient was treated with standard dose of Remdesivir, dexamethasone and antibiotics. But his oxygen demand was increasing day by day. Inflammatory markers including serum ferritin, CRP level was also increasing. Patient was having a cytokine storm. At this point of treatment anti IL6 Tocilizumab was being considered. But patient’s wellbeing was improved and tocilizumab was not given. Our patient gradually recovered from severe COVID-19 pneumonia and cytokine storm without tocilizumab. J MEDICINE JUL 2020; 21 (2) : 119-122

From late December’19 till the end of August 2020, in this nine months period, world has lost more than eight hundred thousands people due to COVID-19 pandemic. Clinical data on COVID-19 in Bangladesh is less. The objective of our study was to evaluate demographic and clinical profile with in a defined period among COVID-19 Bangladeshi Patients in a Tertiary Care Private Medical College Hospital of Dhaka. We conducted a retrospective descriptive study on epidemiological & clinical profile along with short term treatment outcomes of 190 COVID-19 patients from COVID dedicated unit of Popular Medical College Hospital (PMCH) during the period of 18th June to 22nd August 2020 (2 months) with a pre-determined case record form (CRF).Among this 190 patients, mean age was found to be 53 years. Highest percentage of patients (44%) belonged to 41-60 years of age. Regarding gender distribution, two-third patients were male (65%) & one-third patients were female (35%). The predominant symptoms of our enrolled patients were fever (88%),cough (81%) , dyspnoea (58%) & fatigue( 50%). Around half of the patients had been suffering from Hypertension (54%) and Diabetes (47%). Almost half of our patients belonged to moderate severity (48%).The duration of Hospital stay was from 1-36 days, mean was 7 days. There was significant difference for severe and non-severe cases (p value 0.01). J MEDICINE JUL 2020; 21 (2) : 82-88