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result(s) for
"Margherita"
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Le sfide politiche per chi opera nell’ambito sociosanitario
by
Margherita
2025
SUMMARY Political challenges for those working in the health and social sector Italy’s National Health Service (SSN) was established in 1978 with Law 833, finally implementing Article 32 of the Constitution and replacing the previous unequal and fragmented mutual aid system. The new model, inspired by the principle of universality, guarantees every citizen the right to health through a public system funded by general taxation and organized across national, regional, and local levels. Over the years, the SSN underwent several reforms. The 1992 counter-reform (Decree 502) introduced a business-oriented approach, opened the system to private providers, and separated funding and service delivery roles, causing imbalances, increased hospital admissions, and underfunding of prevention. In 1999, the Bindi reform aimed to correct this direction, but was poorly implemented. Since then, Italy’s healthcare has faced chronic underfunding, worsened by the 2008 economic crisis and growing regional inequalities. Recent efforts focus on strengthening local healthcare services through initiatives like the National Recovery and Resilience Plan (PNRR) and the 2022 Ministerial Decree 77, which promote community-based care via structures like Community Health Centers, Territorial Coordination Hubs, and telemedicine. However, realizing these goals requires investment, professional training, unified governance, active local participation, and collaboration with the third sector, to ensure healthcare is equitable, integrated, and truly responsive to people’s needs.
Journal Article
Digital Business Strategy and Value Creation: Framing the Dynamic Cycle of Control Points
2013
Within changing value networks, the profits and competitive advantages of participation reside dynamically at control points that are the positions of greatest value and/or power. The enterprises that hold these positions have a great deal of control over how the network operates, how the benefits are redistributed, and how this influences the execution of a digital business strategy. This article is based on a field study that provides preliminary, yet promising, empirical evidence that sheds light on the dynamic cycle of value creation and value capture points in digitally enabled networks in response to triggers related to technology and business strategy. The context used is that of the European and U.S. broadcasting industry. Specifically, the paper illustrates how incremental innovations may shift value networks from static, vertically integrated networks to more loosely coupled networks, and how cross-boundary industry disruptions may then, in turn, shift those to two-sided markets. Based on the analysis, insights and implications for digital business strategy research and practice are then provided.
Journal Article
Mitochondrial Structure and Bioenergetics in Normal and Disease Conditions
by
Protasoni, Margherita
,
Zeviani, Massimo
in
Adenosine triphosphate
,
Animals
,
Deoxyribonucleic acid
2021
Mitochondria are ubiquitous intracellular organelles found in almost all eukaryotes and involved in various aspects of cellular life, with a primary role in energy production. The interest in this organelle has grown stronger with the discovery of their link to various pathologies, including cancer, aging and neurodegenerative diseases. Indeed, dysfunctional mitochondria cannot provide the required energy to tissues with a high-energy demand, such as heart, brain and muscles, leading to a large spectrum of clinical phenotypes. Mitochondrial defects are at the origin of a group of clinically heterogeneous pathologies, called mitochondrial diseases, with an incidence of 1 in 5000 live births. Primary mitochondrial diseases are associated with genetic mutations both in nuclear and mitochondrial DNA (mtDNA), affecting genes involved in every aspect of the organelle function. As a consequence, it is difficult to find a common cause for mitochondrial diseases and, subsequently, to offer a precise clinical definition of the pathology. Moreover, the complexity of this condition makes it challenging to identify possible therapies or drug targets.
Journal Article
Vibration isolation could boost performance of near-infrared organic LEDs
2024
The development of high-performance organic LEDs and other devices that emit near-infrared light has been hindered by seemingly fundamental features of the light-emitting molecules. A potential solution has been identified.
Decoupling vibrations from electronic transitions.
Journal Article
Taroni : the fabric that dreams are made of
\"A lavish look at the art of Taroni's silk and fashion textiles, which have been found in the haute couture fashions of the world's leading designers, from Dior to Schiaparelli. This book was created with eight different colored covers with silk finishing. Customers will be shipped any of the eight different colors at random. A book about fashion, this volume tells the story of the elegant luxury fabrics of Taroni, who since 1880 have produced fabrics of the highest quality, combining craftsmanship, technology, creativity, and experimentation along the way. A detailed account of the company's history is accompanied by lush images as well as interviews and texts from leading creative figures such as Gianfranco Ferrâe, Roberto Capucci, Alber Elbaz, and other top fashion designers who have worked with Taroni. A virtuous example of Made in Italy where the synergy between technical research and creative work leads to excellent results exported all over the world\"--Publisher's description.
Design rules for organic near-infrared emitters
2024
Sure enough, the combination of charge-transfer character and a non-bonding orbital resulted in strong decoupling of high-frequency vibrations, boosting the efficiency of the NIR emission quantum yield from 14% (for the compound that lacked separation) to 94%. Other researchers have found that OLED performance can be increased by fine-tuning the packing of emitter molecules in the solid state4 and by reducing the frequency of vibrations of carbon-hydrogen bonds in the molecules by substituting the hydrogen atom with a deuterium5. In the past decade, light-induced molecular vibrations have been reported to drive ultrafast reactions6 9 in several molecular systems, and even to be coupled to excitons in biological complexes10.
Journal Article