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"Martin, David"
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The Future of Christianity
This book offers a mature assessment of themes preoccupying David Martin over some fifty years, complementing his book On Secularization. Deploying secularisation as an omnibus word bringing many dimensions into play, Martin argues that the boundaries of the concept of secularisation must not be redefined simply to cover aberrant cases, as when the focus was more on America as an exception rather than on Europe as an exception to the 'furiously religious' character of the rest of the world. Particular themes of focus include the dialectic of Christianity and secularization, the relation of Christianity to multiple enlightenments and modes of modernity, the enigmas of East Germany and Eastern Europe, and the rise of the transnational religious voluntary association, including Pentecostalism, as that feeds into vast religious changes in the developing world. Doubts are cast on the idea that religion has ever been privatised and has lately reentered the public realm. The rest of the book deals with the relation of the Christian repertoire to the nexus of religion and politics, including democracy and violence and sharply criticises polemical assertions of a special relation of religion to violence, and explores the contributions of 'cognitive science' to the debate
eBook
Fighting for Britain : African soldiers in the Second World War
During the Second World War over half a million African troops served with the British army as combatants and non-combatants in campaigns in the Horn of Africa, the Middle East, Italy and Burma. This account, based mainly on oral evidence and soldiers letters, tells the story of the African experience of the war.
Book
Photoredox Activation for the Direct β-Arylation of Ketones and Aldehydes
The direct β-activation of saturated aldehydes and ketones has long been an elusive transformation. We found that photoredox catalysis in combination with organocatalysis can lead to the transient generation of 5π-electron β-enaminyl radicals from ketones and aldehydes that rapidly couple with cyano-substituted aryl rings at the carbonyl β-position. This mode of activation is suitable for a broad range of carbonyl β-functionalization reactions and is amenable to enantioselective catalysis.
Journal Article
Religion and Power
There are few more contentious issues than the relation of faith to power or the suggestion that religion is irrational compared with politics and peculiarly prone to violence. The former claim is associated with Juergen Habermas and the latter with Richard Dawkins.
In this book David Martin argues, against Habermas, that religion and politics share a common mythic basis and that it is misleading to contrast the rationality of politics with the irrationality of religion. In contrast to Richard Dawkins (and New Atheists generally), Martin argues that the approach taken is brazenly unscientific and that the proclivity to violence is a shared feature of religion, nationalism and political ideology alike rooted in the demands of power and social solidarity. The book concludes by considering the changing ecology of faith and power at both centre and periphery in monuments, places and spaces.
eBook
Identification and correction of systematic error in high-throughput sequence data
Background
A feature common to all DNA sequencing technologies is the presence of base-call errors in the sequenced reads. The implications of such errors are application specific, ranging from minor informatics nuisances to major problems affecting biological inferences. Recently developed \"next-gen\" sequencing technologies have greatly reduced the cost of sequencing, but have been shown to be more error prone than previous technologies. Both position specific (depending on the location in the read) and sequence specific (depending on the sequence in the read) errors have been identified in Illumina and Life Technology sequencing platforms. We describe a new type of
systematic
error that manifests as statistically unlikely accumulations of errors at specific genome (or transcriptome) locations.
Results
We characterize and describe systematic errors using overlapping paired reads from high-coverage data. We show that such errors occur in approximately 1 in 1000 base pairs, and that they are highly replicable across experiments. We identify motifs that are frequent at systematic error sites, and describe a classifier that distinguishes heterozygous sites from systematic error. Our classifier is designed to accommodate data from experiments in which the allele frequencies at heterozygous sites are not necessarily 0.5 (such as in the case of RNA-Seq), and can be used with single-end datasets.
Conclusions
Systematic errors can easily be mistaken for heterozygous sites in individuals, or for SNPs in population analyses. Systematic errors are particularly problematic in low coverage experiments, or in estimates of allele-specific expression from RNA-Seq data. Our characterization of systematic error has allowed us to develop a program, called SysCall, for identifying and correcting such errors. We conclude that correction of systematic errors is important to consider in the design and interpretation of high-throughput sequencing experiments.
Journal Article
Peep and Ducky
Illustrations and rhyming text follow two animal friends as they play pretend games, fly down a slide, flop in a puddle, and run around a tree.
Book
Imaging modes of atomic force microscopy for application in molecular and cell biology
This Review Article examines the principles, advantages and limitations of emerging bioimaging modes of atomic force microscopy, including multiparametric, molecular recognition, multifrequency and high-speed imaging.
Atomic force microscopy (AFM) is a powerful, multifunctional imaging platform that allows biological samples, from single molecules to living cells, to be visualized and manipulated. Soon after the instrument was invented, it was recognized that in order to maximize the opportunities of AFM imaging in biology, various technological developments would be required to address certain limitations of the method. This has led to the creation of a range of new imaging modes, which continue to push the capabilities of the technique today. Here, we review the basic principles, advantages and limitations of the most common AFM bioimaging modes, including the popular contact and dynamic modes, as well as recently developed modes such as multiparametric, molecular recognition, multifrequency and high-speed imaging. For each of these modes, we discuss recent experiments that highlight their unique capabilities.
Journal Article