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result(s) for
"Martin, Nicolas, author"
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Global transcriptomic profiles of circulating leucocytes in early lactation cows with clinical or subclinical mastitis
by
Buggiotti, Laura
,
Wylie, Alistair
,
Takeda, Haruko
in
Animal Anatomy
,
Animal Biochemistry
,
Animal production & animal husbandry
2021
Bovine mastitis, an inflammatory disease of the mammary gland, is classified as subclinical or clinical. Circulating neutrophils are recruited to the udder to combat infection. We compared the transcriptomic profiles in circulating leukocytes between healthy cows and those with naturally occurring subclinical or clinical mastitis. Holstein Friesian dairy cows from six farms in EU countries were recruited. Based on milk somatic cell count and clinical records, cows were classified as healthy (n = 147), subclinically (n = 45) or clinically mastitic (n = 22). Circulating leukocyte RNA was sequenced with Illumina NextSeq single end reads (30 M). Differentially expressed genes (DEGs) between the groups were identified using CLC Genomics Workbench V21, followed by GO enrichment analysis. Both subclinical and clinical mastitis caused significant changes in the leukocyte transcriptome, with more intensive changes attributed to clinical mastitis. We detected 769 DEGs between clinical and healthy groups, 258 DEGs between subclinical and healthy groups and 193 DEGs between clinical and subclinical groups. Most DEGs were associated with cell killing and immune processes. Many upregulated DEGs in clinical mastitis encoded antimicrobial peptides (
AZU1, BCL3, CAMP, CATHL1, CATHL2, CATHL4,CATHL5, CATHL6, CCL1, CXCL2, CXCL13, DEFB1, DEFB10, DEFB4A, DEFB7, LCN2, PGLYRP1, PRTN3, PTX3, S100A8, S100A9, S100A12, SLC11A1, TF
and
LTF
) which were not upregulated in subclinical mastitis. The use of transcriptomic profiles has identified a much greater up-regulation of genes encoding antimicrobial peptides in circulating leukocytes of cows with naturally occurring clinical compared with subclinical mastitis. These could play a key role in combatting disease organisms.
Journal Article
Metallic Oxynitride Thin Films by Reactive Sputtering and Related Deposition Methods
2013
This e-book provides valuable information about the process modeling, fabrication and characterization of metallic oxynitride-based thin films produced by reactive sputtering and some related deposition processes.
Natufian Foragers in the Levant
2013,2022
This large volume presents virtually all aspects of the Epipalaeolithic Natufian culture in a series of chapters that cover recent results of field work, analyses of materials and sites, and synthetic or interpretive overviews of various aspects of this important prehistoric culture.
Theory of didactical situations in mathematics : didactique des mathématiques, 1970-1990
1997,2002
This is a collection of texts which give the best presentation of the principles and key concepts of the theory of didactical situations that Guy Brousseau developed in the period from 1970 to 1990. These texts have been edited and organized so that they provide a comprehensive presentation of the theory. Concepts such as didactical contract, didactical variable and epistemological obstacle are presented in detail. At the heart of the book, one will find two works which demonstrate in detail the articulation between theoretical work and experimental research which is the source of the richness of the theory. In order to facilitate the reading of certain points, or elucidate them for the reader, footnotes have been added to the original text, as well as preludes and interludes to place in context the chosen texts and clarify the construction of the book.
Corporate Reputation and the News Media
2011,2010
This volume examines agenda-setting theory as it applies to the news media’s influence on corporate reputation. It presents interdisciplinary, international, and empirical investigations examining the relationship between corporate reputation and the news media throughout the world. Providing coverage of more than twenty-five countries, contributors write about their local media and business communities, representing developed, emerging, and frontier markets – including Argentina, Brazil, Chile, China, Germany, Greece, Japan, Nigeria, Spain, and Turkey, among others. The chapters present primary and secondary research on various geo-political issues, the nature of the news media, the practice of public relations, and the role of public relations agencies in each of the various countries.
Each chapter is structured to consider two to three hypotheses in the country under discussion, including:
the impact of media visibility on organizational prominence, top-of-mind awareness and brand-name recognition
the impact of media favorability on the public’s organizational images of these firms
how media coverage of specific public issues and news topics relates to the associations people form of specific firms.
Contributors contextualize their findings in light of the geopolitical environment of their home countries, the nature of their media systems, and the relationship between business and the news media within their countries’ borders.
Incorporating scholarship from a broad range of disciplines, including advertising, strategic management, business, political communication, and sociology, this volume has much to offer scholars and students examining business and the news media.
Craig E. Carroll (Ph.D., University of Texas at Austin) is Assistant Professor in the School of Journalism and Mass Communication at the University of North Carolina at Chapel Hill.
Introduction -- Craig Carroll, University of North Carolina at Chapel Hill
Section I: Corporate Reputation and the News Media in Developed Markets
United States -- Craig Carroll, University of North Carolina at Chapel Hill
Denmark-- Peter Kjaer, Copenhagen Business School, DK
Finland -- Vilma Luoma-aho, University of Jyväskylä, FL
France -- Roei Davidson, University of Michigan
Germany *-- Guenter Bentele, University of Leipzig
Greece -- Philemon Bantimaroudis, University of the Aegean
Italy -- Davide Ravasi, Bocconi Business School, IT
Japan -- Toshio Takeshito, Meiji University, JP
Netherlands -- May-May Meijer, Free University of Amsterdam
Norway -- Peggy Simcic Brønn, BI Norwegian School of Management
Spain*-- Angel Arrese, Universidad de Navarra
Sweden -- Maria Grafström, Uppsala University, SV
Switzerland -- Mark Eisenegger, University of Zurich, CH
United Kingdom* --Kevin Money, Henley Management College
Australia -- Elizabeth Dougall, University of North Carolina
Section II: Corporate Reputation and the News Media in Emerging Markets
Argentina-- Federico Rey Lennon, Pontificia Universidad Católica AR
Brazil-- Ana Luisa de Castro Almeida, Pontifícia Universidade Católica de Minas Gerais, BR
Chile-- Martin Kunc, Universidad Adolfo Ibañez, CL
China-- Lifeng Deng, Wuhan U, CN
Egypt -- Kevin L. Keenan, American University, Cairo, EG
India--PN Vasanti, Center for Media Research, IN
Israel-- Guy Golan, Seton Hall University
Russia-- Katerina Tsetsura, University of Oklahoma, RU
South Korea-- Heewon Cha, Ewha Women’s University, SK
Turkey-- Serra Görpe, Istanbul University, TK
Section III: Corporate Reputation and the News Media in Frontier Markets
Nigeria-- Tayo Otubanjo, MC Connect, NG
Slovenia-- Dejan Vercic, University of Ljubljana
United Arab Emirates-- Timothy Walters, Zayed University, IR
Section IV: Corporate Reputation and the News Media Around the World: Global Media Literacy
Summary and Future Research-- Craig Carroll, University of North Carolina at Chapel Hill