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Moiré superlattices of two-dimensional heterostructures arose as a new platform to investigate emergent behaviour in quantum solids with unprecedented tunability. To glean insights into the physics of these systems, it is paramount to discover new probes of the moiré potential and moiré minibands, as well as their dependence on external tuning parameters. Hydrostatic pressure is a powerful control parameter, since it allows to continuously and reversibly enhance the moiré potential. Here we use high pressure to tune the minibands in a rotationally aligned MoS 2 /WSe 2 moiré heterostructure, and show that their evolution can be probed via moiré phonons. The latter are Raman-inactive phonons from the individual layers that are activated by the moiré potential. Moiré phonons manifest themselves as satellite Raman peaks arising exclusively from the heterostructure region, increasing in intensity and frequency under applied pressure. Further theoretical analysis reveals that their scattering rate is directly connected to the moiré potential strength. By comparing the experimental and calculated pressure-induced enhancement, we obtain numerical estimates for the moiré potential amplitude and its pressure dependence. The present work establishes moiré phonons as a sensitive probe of the moiré potential as well as the electronic structures of moiré systems. Hydrostatic pressure is an underexplored tuning knob to study moiré systems. Here a MoS 2 /WSe 2 heterostructure is compressed and the enhancement in the moiré potential strength is quantified via moiré-activated Raman modes.

Despite the advanced stage of diamond thin-film technology, with applications ranging from superconductivity to biosensing, the realization of a stable and atomically thick two-dimensional diamond material, named here as diamondene, is still forthcoming. Adding to the outstanding properties of its bulk and thin-film counterparts, diamondene is predicted to be a ferromagnetic semiconductor with spin polarized bands. Here, we provide spectroscopic evidence for the formation of diamondene by performing Raman spectroscopy of double-layer graphene under high pressure. The results are explained in terms of a breakdown in the Kohn anomaly associated with the finite size of the remaining graphene sites surrounded by the diamondene matrix. Ab initio calculations and molecular dynamics simulations are employed to clarify the mechanism of diamondene formation, which requires two or more layers of graphene subjected to high pressures in the presence of specific chemical groups such as hydroxyl groups or hydrogens. The synthesis of two-dimensional diamond is the ultimate goal of diamond thin-film technology. Here, the authors perform Raman spectroscopy of bilayer graphene under pressure, and obtain spectroscopic evidence of formation of diamondene, an atomically thin form of diamond.

Junctions consisting of two crossed single-walled carbon nanotubes were fabricated with electrical contacts at each end of each nanotube. The individual nanotubes were identified as metallic (M) or semiconducting (S), based on their two-terminal conductances; MM, MS, and SS four-terminal devices were studied. The MM and SS junctions had high conductances, on the order of 0.1 e2/h (where e is the electron charge and h is Planck's constant). For an MS junction, the semiconducting nanotube was depleted at the junction by the metallic nanotube, forming a rectifying Schottky barrier. We used two- and three-terminal experiments to fully characterize this junction.

FOCUS (Fast Monte CarlO approach to Coherence of Undulator Sources) is a new GPU‐based simulation code to compute the transverse coherence of undulator radiation from ultra‐relativistic electrons. The core structure of the code, which is written in the language C++ accelerated with CUDA, combines an analytical description of the emitted electric fields and massively parallel computations on GPUs. The combination is rigorously justified by a statistical description of synchrotron radiation based on a Fourier optics approach. FOCUS is validated by direct comparison with multi‐electron Synchrotron Radiation Workshop (SRW) simulations, evidencing a reduction in computation times by up to five orders of magnitude on a consumer laptop. FOCUS is then applied to systematically study the transverse coherence in typical third‐ and fourth‐generation facilities, highlighting peculiar features of undulator sources close to the diffraction limit. FOCUS is aimed at fast evaluation of the transverse coherence of undulator radiation as a function of the electron beam parameters, to support and help prepare more advanced and detailed numerical simulations with traditional codes like SRW. FOCUS (Fast Monte CarlO approach to Coherence of Undulator Sources), a new GPU‐based code to compute the transverse coherence of X‐ray radiation from undulator sources as a function of the electron beam parameters, is described. FOCUS is validated with the Synchrotron Radiation Workshop (SRW) and SPECTRA codes. Examples of application to coherence studies in third‐ and fourth‐generation light sources are shown.

We report our single-center experience on the neurological manifestations of long COVID. This is a retrospective observational study. All consecutive patients referred to the neurological long COVID outpatient clinic of our institute from January 21 2021 to December 9 2021 underwent a general neurological objective examination. Treatments and investigations (brain MRI, neuropsychological evaluation, or others) were prescribed on an individual basis as per standard clinical practice. A follow-up visit was performed when appropriate. Descriptive statistics were presented as absolute and relative frequencies for categorical variables and as means, median, and ranges for continuous variables. One hundred and three patients were visited (mean age 50.5 ±36 years, 62 females). The average time from acute COVID-19 infection to the first visit to our outpatient clinic was 243 days. Most patients presented with a mild form of acute COVID-19, with only 24 cases requiring hospitalization. The neurological symptoms mostly (n=70/103, 68%) started during the acute phase (before a negative swab for SARS-CoV-2). The most frequent acute manifestations reported, which lately became persistent, were fatigue (n=58/103, 56%), olfactory/taste dysfunction (n=58/103, 56%), headache (n=47/103, 46%), cognitive disorders (n=46/103, 45%), sleep disorders (n=30/103, 29%), sensitivity alterations (n=29/103, 28%), and dizziness (n=7/103, 7%). Tremor was also reported (n=8/103, 7%). Neuropsychological evaluation was performed in 30 patients and revealed alterations in executive functions (n=6/30, 20%), memory (n=11/30, 37%), with pathological depressive (n=9/30, 30%) and anxiety (n=8/30, 27%) scores. Brain MRIs have been performed in 41 cases, revealing nonspecific abnormal findings only in 4 cases. Thirty-six patients underwent a follow-up, where a general improvement was observed but rarely (n=2/36) a complete recovery. The majority of patients presenting persistent neurological symptoms (most frequently fatigue, cognitive disorders, and olfactory dysfunctions) developed a previous mild form of COVID-19. Further studies are required to develop therapeutic strategies.

This paper describes a new protocol for mandibular reconstruction. Computer-aided design/computer-aided manufacturing (CAD/CAM) technology was used to manufacture custom-made cutting guides for tumor ablation and reconstructive plates to support fibula free flaps. CT scan data from a patient with an odontogenic keratocyst on the left mandibular ramus were elaborated to produce a virtual surgical plan of mandibular osteotomy in safe tissue for complete ramus resection. The CAD/CAM procedure was used to construct a customized surgical device composed of a cutting guide and a titanium reconstructive bone plate. The cutting guide allowed the surgeon to precisely transfer the virtual planned osteotomy into the surgical environment. The bone plate, including a custom-made anatomical condylar prosthesis, was designed using the outer surface of the healthy side of the mandible to obtain an ideal contour and avoid the bone deformities present on the side affected by the tumor. Operation time was reduced in the demolition and reconstruction phases. Functional and aesthetic outcomes allowed patients to immediately recover their usual appearance and functionality. This new protocol for mandibular reconstruction using CAD/CAM to construct custom-made guides and plates may represent a viable way to reproduce the patient’s anatomical contour, give the surgeon better procedural control, and reduce operation time.

We present the observation and the detailed investigation of coherent Cherenkov diffraction radiation (CChDR) in terms of spectral-angular characteristics. Electromagnetic simulations have been performed to optimize the design of a prismatic dielectric radiator and the performance of a detection system with the aim of providing longitudinal beam diagnostics. Successful experimental validations have been organized on the CLEAR and the CLARA facilities based at CERN and Daresbury laboratory respectively. With ps to sub-ps long electron bunches, the emitted radiation spectra extend up to the THz frequency range. Bunch length measurements based on CChDR have been compared to longitudinal bunch profiles obtained using a radio frequency deflecting cavity or coherent transition radiation (CTR). The retrieval of the temporal profile of both Gaussian and non-Gaussian bunches has also been demonstrated. The proposed detection scheme paves the way to a new kind of beam instrumentation, simple and compact for monitoring short bunches of charged particles, particularly well-adapted to novel accelerator technologies, such as dielectric and plasma accelerators. Finally, CChDR could be used for generating intense THz radiation pulses at the MW level in existing radiation facilities, providing broader opportunities for the user community.

In this paper we report on recent two-dimensional (2D) electron beam size measurements with a nonconventional synchrotron radiation interferometric technique based on x-ray heterodyne near field speckles (HNFS). The method relies on Fourier analysis of the random speckle patterns generated by a water suspension of nanospheres to assess the full 2D transverse coherence of the incoming x rays. The horizontal and vertical electron beam sizes are then retrieved by means of statistical optics approaches. The manuscript thoroughly describes the HNFS technique, and shows experimental results obtained at the ALBA Synchrotron Light Source. By changing the machine coupling, beam sizes as small as5μmare measured, thus improving on past measurements reported in the literature and proving the HNFS diagnostics suitable for low-emittance particle beams.

In this article, we briefly summarize the experiments performed during the first run of the Advanced Wakefield Experiment, AWAKE, at CERN (European Organization for Nuclear Research). The final goal of AWAKE Run 1 (2013–2018) was to demonstrate that 10–20 MeV electrons can be accelerated to GeV energies in a plasma wakefield driven by a highly relativistic self-modulated proton bunch. We describe the experiment, outline the measurement concept and present first results. Last, we outline our plans for the future. This article is part of the Theo Murphy meeting issue ‘Directions in particle beam-driven plasma wakefield acceleration’.

In recent years, there has been an increasing demand for noninvasive beam size monitoring on particle accelerators. Ideally, these monitors should be cost effective and require little or no maintenance. These monitors should also be suitable for both linear and circular machines. Here, the experimental setup is described in detail, and the results from a diffraction radiation beam size monitor are presented. This monitor has been tested on the Cornell Electron Storage Ring using a 1 mA (1.6×1010particles per bunch) single bunch electron beam at 2.1 GeV energy. Images of the target surface and the angular distribution of the emitted diffraction radiation were acquired at wavelengths of 400 and 600 nm. These measurements are compared to two analytical models.