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This collection explores critical and visual practices through the lens of interactions and intersections between pattern and chaos. The dynamic of the inter-relationship between pattern and chaos is such as to challenge disciplinary boundaries, critical frameworks and modes of understanding, perception and communication, often referencing the in-between territory of art and science through experimentation and visual scrutiny. A territory of 'pattern-chaos' or 'chaos-pattern' begins to unfold. Drawing upon fields such as visual culture, sociology, physics, neurobiology, linguistics or critical theory, for example, contributors have experimented with pattern and/or chaos-related forms, processes, materials, sounds and language or have reflected on the work of other artists, scientists and scholars. Diagrams, tessellations, dust, knots, mazes, folds, creases, flux, virus, fire and flow are indicative of processes through which pattern and chaos are addressed. The contributions are organized into clusters of subjects which reflect the interdisciplinary terrain through a robust, yet also experimental, arrangement. These are 'Pattern Dynamics', 'Morph Flux Mutate', 'Decompose Recompose', 'Virus; Social Imaginary' and 'Nothings in Particular'.

Successful product and process design depends on management's ability to integrate fragmented pockets of specialized knowledge. This integrative capability has important implications for large-scale information technology projects. This article examines the relationship between timely project completion and two dimensions of management's integrative capability: access to external knowledge and internal knowledge integration. Measures of these two dimensions are used to predict on-time project completion, where completion is a function of the duration of IT-related project delays. In a longitudinal study of 74 enterprise application integration projects in the medical sector, integrative capability was measured from the point of view of the CIO and a facility IT manager. Accounting for several project controls, our Cox regression results indicate both integrative dimensions significantly mitigate the duration of IT-related project delays, thus promoting timely project completion. The analysis also reveals the importance of taking management structure into consideration when studying IT phenomena in networked organizations.

We examine whether cooperative planning and uncertainty affect the magnitude of rework in concurrent engineering projects with upstream and downstream operations, and explore the impact of such rework on project delays. Using survey data from a sample of 120 business process (BP) redesign and related information technology (IT) development projects in healthcare and telecommunications, our results indicate that upstream (BP) rework and downstream (IT) rework is mediated and mitigated by cooperative planning through upstream/downstream strategy coupling and cross-functional involvement. In addition, uncertainty related to a lack of firm or industry experience with such projects increases the magnitude of upstream rework but not downstream rework or the amount of cooperative planning. After accounting for project scope, implementation horizon and whether delays are anticipated, we find that project delay is primarily influenced by the magnitude of downstream rework and downstream delay: the magnitude of both upstream and downstream rework significantly increases downstream delay, which significantly increases project delay. However, the magnitude of upstream rework does not directly affect project delay. These results suggest that project delay is under managerial control as cooperative planning is a managerial function that reduces downstream rework, while uncertainty from a lack of experience with the design affecting upstream rework is not directly under managerial control.

The redesign of information technology (IT)‐enabled work processes often necessitates fundamental design changes to the intended work process, the IT platform hosting the work process, or both. Research suggests that such design changes often can be traced to earlier decisions involving endogenous adaptation or internal organizational change. Two such decisions are a firm's technology position and planning mode. This study examines the relationship between technology position and planning mode in predicting the magnitude of design change in process redesign projects. The conceptual frame applied in examining these relationships involves a synthesis of Miles and Snow's adaptive cycle with elements central to concurrent engineering. Our results indicate that the magnitude of design change is related to differences in technology position and planning mode. To effectively implement organizational change, firms must leverage their IT platform by carefully timing IT investments in accordance with their adopted technology position. Directing the trajectory of a firm's IT platform and deploying it so as to complement the firm's technology position reduces design uncertainty, promoting reengineering success.

American badgers (Taxidea taxus) are a semi fossorial mammal that lives in grassland and open prairie ecosystems as well as coastal prairies, agricultural fields, deserts, and deforested habitats. Many researchers have published work on badgers, but we still require more information on their ecology. The American badger is a semi fossorial, solitary, predatory mammal of grassland ecosystems. They are classified as mesopredators when compared to larger apex predators such as brown bears, wolves, and pumas. However, when larger carnivores are absent, Badgers become apex predators of their ecosystems. Los Vaqueros Watershed in Brentwood, California, was my study site because badgers had been the most active at that site than at the other two. During this study, I collected data at 10 badger burrows and 10 randomly located sites from November 11, 2022, to March 14, 2024. American badgers prefer open prairies and grasslands and are more likely to inhabit open-field habitats in open prairies and grasslands than in coastal prairies, which have less space due to woody vegetation occupying some of the ecosystem. There needs to be more data on the estimated populations of American badgers throughout the San Francisco Bay Area to determine whether our new wildlife management skills will work for the badgers.

Organizational adaptation to competition often means inventing or adopting a process innovation and the daunting challenge of implementing it. Increasingly, process innovations rely on the capabilities embedded in an organization's IT infrastructure. Successfully implementing an IT-enabled process innovation depends largely on how a project's IT and work process designs fit and evolve with this IT infrastructure. However, little empirical research guides the formulation of IT and work process strategies. This study addresses the question: How does the degree of coupling between a redesign project's IT strategy and work process strategy affect project performance? Data collection utilized a multistage research design employing comprehensive phone interviews and matched surveys among three sets of respondents (project managers, IT managers, and process users) across 43 process redesign projects in the health care industry. Our findings indicate project performance improves with tightly coupled IT and work process strategies when implementing process inventions, and with loosely coupled strategies when implementing imitations.

Patients with Alzheimer’s disease (AD) with little or no quantifiable insoluble brain tau neurofibrillary tangle (NFT) pathology demonstrate stronger clinical benefits of therapies than those with advanced NFTs. The formation of NFTs can be prevented by targeting the intermediate soluble tau assemblies (STAs). However, biochemical understanding and biomarkers of STAs are lacking. We show that Tris-buffered saline-soluble tau aggregates from autopsy-verified AD brain tissues include the core sequence ~tau 258–368 . In neuropathological assessments, antibodies against the phosphorylation sites serine-262 and serine-356 within the STA core almost exclusively stained granular (that is, prefibrillar) tau aggregates in pre-NFTs while antibodies against phosphorylation at serine-202 and threonine-205 and threonine-231, outside the STA core, stained the entire spectrum of tau aggregates in pre-NFTs and mature NFTs, dystrophic neurites and neuropil threads in the hippocampus. Functionally, a recombinantly produced STA core peptide robustly altered neuronal excitability and synaptic transmission in mouse hippocampal brain slices. Furthermore, we developed a cerebrospinal fluid assay that differentiated STAs in AD from non-AD tauopathies, correlated with the severity of NFT burden and cognitive decline independently of amyloid beta deposition, and with tau positron emission tomography uptake across Braak NFT stages. Together, our findings inform about the status of early-stage tau aggregation, reveal aggregation-relevant phosphorylation epitopes in tau and offer a diagnostic biomarker and targeted therapeutic opportunities for AD. Two new phosphorylation sites, p-tau 262 and p-tau 356 , detect the formation of prefibrillar tau aggregates and may serve as early-stage biofluid-based biomarkers of tau neurofibrillary tangle pathology in Alzheimer’s disease.

Successful product and process design depends on management’s ability to integrate fragmented pockets of specialized knowledge. This integrative capability has important implications for large-scale information technology projects. This article examines the relationship between timely project completion and two dimensions of management’s integrative capability: access to external knowledge and internal knowledge integration. Measures of these two dimensions are used to predict on-time project completion, where completion is a function of the duration of IT-related project delays. In a longitudinal study of 74 enterprise application integration projects in the medical sector, integrative capability was measured from the point of view of the CIO and a facility IT manager. Accounting for several project controls, our Cox regression results indicate both integrative dimensions significantly mitigate the duration of IT-related project delays, thus promoting timely project completion. The analysis also reveals the importance of taking management structure into consideration when studying IT phenomena in networked organizations.

The problem addressed in this qualitative comparative case study was that digital devices such as smartphones, iPads, and laptop computers can have both positive and negative effects on student learning when used as learning tools within instruction. The purpose of this study was to explore how teachers used digital devices as learning tools in instruction, how teachers managed device use, and how teacher’s perceptions of device use for student learning influenced the way these devices were used in instruction. Data was collected from two high schools. Potential participants completed a survey through email invitation to determine eligibility. Possible participants who meet eligibility requirements were chosen randomly to include 8 teachers from each study site who taught core subjects of English, mathematics, the sciences and social studies. Site permissions and Institutional Review Board permission were obtained prior to data collection. Data was collected through semi-structured interviews and classroom observations. Informed consent was obtained from all participants. Data was analyzed using ATLAS.ti software to identify emergent, convergent, and divergent themes both within and across cases. . The results from this study revealed that when teachers used digital devices in engaging ways that encourage students to explore and expand the curriculum, student engagement was increased, and distractions were decreased. The results of this study added to the literature by deepening the understanding of digital devices used as learning tools in instruction from the perspectives of the teachers. The results may aid in the development of classroom strategies that will help teachers use and manage digital device use effectively.