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Lead (Pb), cadmium (Cd), and mercury (Hg) are heavy metals that can cause strong biological effects. Some foods can neutralize or detoxify toxins and protect the liver from the toxic effects of heavy metals. These foods included garlic, ginger, carrot, corn, aloe vera, honey, milk thistle and Dates. The main objective of the present study was to indorse specific food formulas as detoxifying to minimize the harmful effect of lead, cadmium, and mercury. In this study, we investigated the effect of some foods on the toxicity of cadmium chloride (150 mg/l), mercury chloride (80 mg/l) and lead acetate (160 mg/l) in drinking water for 4 weeks on liver function of male rats. The results indicated that garlic, ginger, and milk thistles (formula 1) and garlic, ginger, carrot, corn, date mesocarp (pulp), aloe vera, and honey (formula 2) decrease the activity of the serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) and malondialdehyde (MDA) While increase Catalase (CAT) activity. Also (formula 2) recorded the best results compared with (formula 1). The pathological study of the tissues showed a complete improvement in the liver tissues after lead, cadmium and mercury caused severe liver damage. Concomitant use of (formula 2) and (formula 1) was found to reduce lead, cadmium and mercury concentration considerably indicating the potential therapeutic activity of (formula 2) and (formula 1) against heavy metals toxicity.

The study aims to evaluate the effect of germinated and fermented red radish seeds in alleviating liver and kidney toxicity induced by cadmium in experimental rats. The results showed that red radish seeds contributed to reducing the elevated levels of certain biochemical markers such as ALT, asing the activity of antioxidant AST, urea, creatinine, and MDA, while increreduction in organ damage, particularly when both enzymes, leading to a germinated and fermented seeds were used together

Background and Objectives: A cesarean scar defect (CSD), also referred to as a niche or isthmocele, is often detected incidentally during transvaginal sonography (TVS) and is typically asymptomatic. However, the exact prevalence of symptomatic niches remains unclear. This study aimed to evaluate the incidence of cesarean scar niches and identify potential risk factors in a prospectively gathered cohort of Egyptian women. Materials and Methods: The primary endpoint was to determine the incidence of isthmoceles after six months following a cesarean section (CS) and to investigate any associated symptoms and risk factors. The study included 420 women, divided into three groups: Group A included 140 women who had undergone their first CS, Group B included 140 women with a history of two CSs, and Group C consisted of 140 women with more than two prior CSs. Results: Niches were identified in 23.8% of the participants via TVS. The highest incidence was observed in women with more than two previous CSs (31.2%, 39/125), followed by those with two prior CSs (24.4%, 30/123), and the lowest was among women with one previous CS (16.3%, 22/135). Of the 91 women diagnosed with a CS niche, only 23 (25.27%) reported symptoms—most commonly postmenstrual spotting (7.7%) and dyspareunia (8.8%). Conclusions: The findings indicate that multiple cesarean deliveries, the uterine positioning (as assessed via TVS), a postpartum fever, breastfeeding, low post-cesarean platelet counts, and maternal anemia are contributing factors to the development of cesarean scar niches.