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McMahon Hall, an iconic Brutalist dormitory at the University of Washington, has become the site of an interdisciplinary experiment in cultural memory and machine-assisted storytelling. This article presents a method that combines remote sensing with AI-generated voices to produce a polyvocal narrative of architecture through the perspective of the building itself, its material (concrete), an architect, a journalist, and a bird. Drone photogrammetry and generated 3D models were combined with generative AI (text, image, and voice) to reconstruct the site digitally and imaginatively (AI-driven speculative narratives). Through speculative storytelling, the article and the project explore how cultural memory and perception of built heritage can be augmented by machines, offering plural perspectives that challenge singular historical narratives. The Introduction situates the work at the intersection of digital heritage documentation, AI storytelling, epistemology in machine learning, and spatial computing, emphasizing the perception of heritage through different actors. The Theoretical Framework draws on literature in photogrammetry for heritage preservation, polyvocal narrative, and knowledge frameworks of AI. The Materials and Methods detail the workflow: capturing McMahon Hall via UAV photogrammetry, producing a 3D model, and generating character-driven narratives with large language models and voice synthesis. The resulting multi-voiced narrative and its thematic insights are described. In the Discussion, the implications of this approach for architectural heritage interpretation are considered, including its capacity to amplify diverse voices and the risks of bias or hyperreality in AI-generated narratives. The study argues that this polyvocal, machine-augmented storytelling expands the toolkit of remote sensing and digital heritage by not only documenting the tangible form of the built environment but also speculating on its intangible cultural memory. The Conclusions reflect on how merging spatial computing techniques with AI narratives can support new modes of engagement with architecture, positioning this work as a building block toward richer human-machine co-created heritage experiences.

This paper explores the value of imperfections and curated decay in the conservation of architecture and public art as vehicles of cultural memory. While conventional heritage practice treats physical degradation as a threat, newer conservation ethics argue for embracing material impermanence within an aesthetics of care. We examine how acknowledging patina, weathering, and even structural decline can become an act of care, maintaining the “spirit” and authenticity of a place. The theoretical framework integrated the aesthetics of imperfection, including concepts like the Japanese wabi-sabi, which finds beauty in the incomplete and impermanent, critical heritage theory (which questions whose memories and values are preserved or excluded) and cultural memory studies (notably Nora’s notion of lieux de mémoire, where material sites become symbolic elements of communal memory). Methodologically, the article is grounded by two case-study video essays, Imperfections (Genoa) and Scars (Nicosia), as instruments of research, which provide visual analyses of decayed architectural environments. These examples illustrate how curated decay can transform abandoned buildings and war-scarred urban zones into powerful mnemonic devices, provoking reflection on history, identity and the ethics of preservation. Despite extensive theorisation of patina/age-value and curated decay, recent heritage debates offer limited operational criteria for distinguishing intentional curated decay from unmanaged neglect in lived urban conservation contexts. Drawing on ethics and aesthetics of care, this article asks if and how care can be operationalised into a decision framework for urban conservation and tests this framework through two selected buildings: Albergo dei Poveri (Genoa) and Home for Cooperation (Nicosia). The authors argue that caring for heritage does not always mean restoring it to an as-new state; curating ageing and traces of time can support remembrance, resilience, and reconciliation, enriching heritage’s role in future urban imaginaries.

Mid-century Brutalist buildings are frequently documented as objects of form, yet their contested reception and lived memory are less often addressed in architectural education. This article analyses the results of an interdisciplinary experiment centred on McMahon Hall during the summer school Rhetorical Machine + the Hyperlocal at the University of Washington. The method pairs UAV and close-range photogrammetry with a retrieval-augmented, persona-based generative AI workflow to produce a polyvocal narrative grounded in curated site-specific sources. The article argues that this combined method offers a transferable pedagogical model through which students can document both the measurable and intangible dimensions of the built environment while developing technical, interpretive, and ethical competencies.

Medically underserved people with type 2 diabetes mellitus face limited access to group-based diabetes care, placing them at risk for poor disease control and complications. Immersive technology and telemedicine solutions could bridge this gap. The purpose of this study was to compare the effectiveness of diabetes medical group visits (DMGVs) delivered in an immersive telemedicine platform versus an in-person (IP) setting and establish the noninferiority of the technology-enabled approach for changes in hemoglobin A (HbA ) and physical activity (measured in metabolic equivalent of task [MET]) at 6 months. This study is a noninferiority randomized controlled trial conducted from February 2017 to December 2019 at an urban safety net health system and community health center. We enrolled adult women (aged ≥18 years) who self-reported African American or Black race or Hispanic or Latina ethnicity and had type 2 diabetes mellitus and HbA ≥8%. Participants attended 8 weekly DMGVs, which included diabetes self-management education, peer support, and clinician counseling using a culturally adapted curriculum in English or Spanish. In-person participants convened in clinical settings, while virtual world (VW) participants met remotely via an avatar-driven, 3D VW linked to video teleconferencing. Follow-up occurred 6 months post enrollment. Primary outcomes were mean changes in HbA and physical activity at 6 months, with noninferiority margins of 0.7% and 12 MET-hours, respectively. Secondary outcomes included changes in diabetes distress and depressive symptoms. Of 309 female participants (mean age 55, SD 10.6 years; n=195, 63% African American or Black; n=105, 34% Hispanic or Latina; n=151 IP; and n=158 in VW), 207 (67%) met per-protocol criteria. In the intention-to-treat analysis, we confirmed noninferiority for primary outcomes. We found similar improvements in mean HbA by group at 6 months (IP: -0.8%, SD 1.9%; VW: -0.5%, SD 1.8%; mean difference 0.3, 97.5% CI -∞ to 0.3; P<.001). However, there were no detectable improvements in physical activity (IP: -6.5, SD 43.6; VW: -9.6, SD 44.8 MET-hours; mean difference -3.1, 97.5% CI -6.9 to ∞; P=.02). The proportion of participants with significant diabetes distress and depressive symptoms at 6 months decreased in both groups. In this noninferiority randomized controlled trial, immersive telemedicine was a noninferior platform for delivering diabetes care, eliciting comparable glycemic control improvement, and enhancing patient engagement, compared to IP DMGVs. ClinicalTrials.gov NCT02726425; https://clinicaltrials.gov/ct2/show/NCT02726425.

While oral anticoagulants (OACs) are highly effective for ischemic stroke prevention in atrial fibrillation, intracerebral hemorrhage (ICH) remains the most feared complication of OAC. Clinical controversy remains regarding OAC resumption and its timing for ICH survivors with atrial fibrillation because the balance between risks and benefits has not been investigated in randomized trials. To survey the practice of stroke neurologists, thrombosis experts and neurosurgeons on OAC re-initiation following OAC-associated ICH. An online survey was distributed to members of the International Society for Thrombosis and Haemostasis, Canadian Stroke Consortium, NAVIGATE-ESUS trial investigators (Clinicatrials.gov identifier NCT02313909) and American Association of Neurological Surgeons. Demographic factors and 11 clinical scenarios were included. Two hundred twenty-eight participants from 38 countries completed the survey. Majority of participants were affiliated with academic centers, and >20% managed more than 15 OAC-associated ICH patients/year. Proportion of respondents suggesting OAC anticoagulant resumption varied from 30% (for cerebral amyloid angiopathy) to 98% (for traumatic ICH). Within this group, there was wide distribution in response for timing of resumption: 21.4% preferred to re-start OACs after 1-3 weeks of incident ICH, while 25.3% opted to start after 1-3 months. Neurosurgery respondents preferred earlier OAC resumption compared to stroke neurologists or thrombosis experts in 5 scenarios (p<0.05 by Kendall's tau). Wide variations in current practice exist among management of OAC-associated ICH, with decisions influenced by patient- and provider-related factors. As these variations likely reflect the lack of high quality evidence, randomized trials are direly needed in this population.

Maritime transport is one of the main activities of the blue economy, which plays an important role in the EU. In this paper, we aim to assess the impact of maritime transport, related investment, and air pollution on economic growth within 20 countries of the European Union, using eight panel data regression models from 2007 to 2018. Our results confirm that maritime transport, air pollutants (NOx and SO2) from maritime transport, and investment in maritime port infrastructure are indeed positively correlated with economic growth. In other words, an increase of 10% in these factors has generated an associated increase in economic growth rate of around 1.6%, 0.4%, 0.8%, and 0.7% respectively. Alongside the intensity of economic maritime activities, pollution is positively correlated with economic growth, and thus it is recommended that policymakers and other involved stakeholders act to diminish environmental impacts in this sector using green investment in port infrastructure and ecological ships, in accordance with the current European trends and concerns.

Glioblastoma multiforme (GBM) is one of the deadliest brain tumors. Current standard therapy includes tumor resection surgery followed by radiotherapy and chemotherapy. Due to the tumors invasive nature, recurrences are almost a certainty, giving the patients after diagnosis only a 12–15 months average survival time. Therefore, there is a dire need of finding new therapies that could potentially improve patient outcomes. Ferroptosis is a newly described form of cell death with several implications in cancer, among which GBM. Agents that target different molecules involved in ferroptosis and that stimulate this process have been described as potentially adjuvant anti-cancer treatment options. In GBM, ferroptosis stimulation inhibits tumor growth, improves patient survival, and increases the efficacy of radiation and chemotherapy. This review provides an overview of the current knowledge regarding ferroptosis modulation in GBM.

Background Basal meningoceles are rare herniations of the meninges that tend to present unilaterally with cerebrospinal fluid rhinorrhea. Growing evidence suggests that intracranial hypertension contributes considerably to the formation of spontaneous basal meningoceles. Case presentation A 50-year-old man of Middle East ethnicity presented with a 16-week history of cerebrospinal fluid rhinorrhea, short-term memory loss, and slight decline in cognitive function. We present a case of bilateral spontaneous meningoceles with bone defects in the left lateral sphenoid sinus and right anterior cribriform plate, as well as with a remodeled sella. A neuronavigation-assisted expanded endoscopic endonasal surgery was performed to resect the meningoceles. Postoperative imaging demonstrated complete resolution of the bilateral meningoceles. Conclusions This case reports the first bilateral basal spontaneous meningoceles in the literature. Furthermore, based on this case’s imaging results and the literature reviewed, elevated intracranial pressure may be a determining factor behind the development of spontaneous meningoceles.

Geraniums (pelargoniums or storksbills, officially named as Pelargonium zonale (L.) L'Hér. Ex Aiton) are appreciated worldwide due to their ornamental potential and versatility. The research was conducted to emphasize the evolution of morpho-decorative and qualitative traits of two geranium cultivars of high aesthetic value, namely ‘Tango Salmon’ (Montevideo) and ‘Tango Dark Red’, depending on two different fertilization, conventional-chemical fertilization, and unconventional scheme, with a homeopathic solution respectively. It is excessive repetitiveness and is not the case.) cultivar, unconventional fertilization scheme tested conducted to the best results regarding most morpho-decorative characters investigated (33.40 cm height, 21.10 leaves/plant, 34.75 flowers/inflorescence, 2.35% nitrogen, and 48.34 SPAD). For cultivar ‘Tango Dark Red’, the conventional fertilization conducted to the best results in terms of height (18.90 cm), stems/plant (5.90), leaves/plant (14.95), and flowers/inflorescence (37.55), while unconventional fertilization led to higher nitrogen accumulation (2.18%) and enhanced chlorophyll synthesis (47.08 SPAD). Between nitrogen and chlorophyll contents within geranium leaves, strong positive correlations were identified in ‘Tango Salmon’, and weak to moderate in ‘Tango Dark Red’ cultivar. Higher scores were attributed to aesthetic indicators for ‘Tango Salomon’ compared to ‘Tango Dark Red’. The unconventional fertilization of geranium cultivars is an eco-friendly solution for enhancing their morpho-decorative characteristics.

[This corrects the article DOI: 10.1371/journal.pone.0191137.].