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Efforts to disseminate heat-related illness (HRI) prevention practices among Latino farmworkers represent a critical occupational safety strategy in Florida. Targeted initiatives, however, require understanding the workplace dynamics that guide agricultural safety behaviors. This article reports focus group data collected in 2018 from citrus harvesters in central Florida and provides an in-depth perspective on the workplace culture that shapes their implementation of heat safety measures. Results indicate that citrus harvesters regularly suffered HRI symptoms yet rarely reported or sought treatment for their injuries. In some cases, the risks of developing HRI were accepted as a facet of agricultural work and harvesters blamed themselves for their illnesses. Implementation of safety practices hinged less on knowledge than on the availability of water and rest breaks and the quality of employer-employee relations and exchanges. Thus, trust was a determinant of workers’ attitudes toward management that contributed to a harvesting operation’s safety climate. Results highlight the difficulties of putting into practice measures that are not rewarded by the workplace culture and suggest that the extent to which intervention strategies promote not only individual safety behaviors but organizational accountability may predict their effectiveness.

Efforts to mitigate outdoor water use in Florida’s urban landscapes increasingly include promotion of regionally appropriate landscaping based on its documented effectiveness. Targeted initiatives, however, require an understanding of mechanisms underpinning low irrigation use in single-family homes with Florida-Friendly Landscaping (FFL). This paper reports survey research conducted in southwest Florida to identify factors associated with irrigation practices among FFL clients. Results indicate that approximately half of survey participants irrigated less frequently than once per week year-round. Aesthetic considerations, horticultural knowledge, and membership in a homeowner’s association (HOA) with rules regarding yard care were key variables underlying landscape characteristics and maintenance, while property values, water conservation attitudes, lawn grass, and in-ground irrigation system use significantly predicted irrigation practices. Homes with in-ground irrigation systems were more than six times more likely to water their landscapes at least once per week during the warm season when residential outdoor water use is at its peak. A $100,000 increase in a home’s market value increased the odds of weekly watering by a multiplicative factor of two, whereas a one-point increase in a six-item Likert scale used to measure a homeowner’s water conservation attitude decreased the odds by 76%. Homes with no grass in the landscape were 71% less likely to water on a weekly basis. Providing homeowners, and HOAs, with educational resources that build on existing support for water conservation could augment adoption of low maintenance plants and sustainable practices in Florida’s urban landscapes.

Objectives. Although eye injuries are common among citrus harvesters, the proportion of workers using protective eyewear has been negligible. We focused on adoption of worker-tested safety glasses with and without the presence and activities of trained peer-worker role models on harvesting crews. Methods. Observation of 13 citrus harvesting crews established baseline use of safety eyewear. Nine crews subsequently were assigned a peer worker to model use of safety glasses, conduct eye safety education, and treat minor eye injuries. Safety eyewear use by crews was monitored up to 15 weeks into the intervention. Results. Intervention crews with peer workers had significantly higher rates of eyewear use than control crews. Intervention exposure time and level of worker use were strongly correlated. Among intervention crews, workers with 1 to 2 years of experience (odds ratio [OR] = 2.89; 95% confidence interval [CI] = 1.11, 7.55) and who received help from their peer worker (OR = 3.73; 95% CI = 1.21, 11.57) were significantly more likely to use glasses than were other intervention crew members. Conclusions. Adaptation of the community health worker model for this setting improved injury prevention practices and may have relevance for similar agricultural settings.

Smart irrigation controllers are capable of substantially decreasing landscape water applications under residential high water-use conditions in Florida. Their implementation has been incentivized by governmental agencies and water utilities in an effort to reduce public-supply water demand and conserve water resources. However, the bulk of the research on smart controllers for urban landscapes has focused on performance dimensions. To successfully promote them, feedback from end-users is critical. This paper provides an evaluation of homeowner response to evapotranspiration (ET)-based and soil moisture sensor (SMS)-based smart controllers installed as part of a pilot project conducted in Orange County, FL. The objectives of the study were to collect demographic information, assess conservation attitudes and irrigation system knowledge, and gather feedback on the use of smart controllers from the pilot project’s residential cooperators. Data were collected through an online survey and analyzed using relative frequency distributions, text analysis, independent means t tests, and logistic regression. Results indicated that a majority of survey participants were satisfied with their controllers and planned to continue using them. Both ET and SMS controllers were consistently praised for saving money and irrigating efficiently. However, the likelihood that participants would continue using their controllers after the completion of the project was only significantly predicted by their levels of technical knowledge regarding the workings of the devices and whether they had experienced any challenges operating them. Efforts to promote both initial and long-term adoption may be most effective by emphasizing the economic benefits of investing in smart irrigation controllers and by disseminating best management practices that facilitate their understanding and successful operation.

The community-based prevention marketing program planning framework was used to adapt an evidence-based intervention to address eye injuries among Florida’s migrant citrus harvesters. Participant-observer techniques, other direct observations, and individual and focus group interviews provided data that guided refinement of a safety eyewear intervention. Workers were attracted to the eyewear’s ability to minimize irritation, offer protection from trauma, and enable work without declines in productivity or comfort. Access to safety glasses equipped with worker-designed features reduced the perceived barriers of using them; deployment of trained peer-leaders helped promote adoption. Workers’ use of safety glasses increased from less than 2% to between 28% and 37% in less than two full harvesting seasons. The combination of formative research and program implementation data provided insights for tailoring an existing evidence-based program for this occupational community and increase potential for future dissemination and worker protection.

In safety, health, environment and quality, three categories of compliance are evident: voluntary; legal/mandatory; and corporate. Compliance management in, for example, the supply chain relates to 'business support' or 'integrated management systems', which supplement front-line operational transactions. The multiplier effect in compliance management-related activity across many more areas of business means that organisations are looking to Information Technology (IT) to manage that activity. The software, Q SET Groupware, consists of eight modules that can be used as a stand-alone tool to manage a specific aspect of compliance, or combined into an integrated total-compliance tool. Waterford Crystal wanted an IT platform to support compliance management in the supply chain. ALSTOM Power wanted a fully integrated quality, environment, and health and safety software system running on Lotus Notes to support ISO 9000, ISO 14000 and, eventually, SMS 8800/OHSAS 18001, and to eliminate duplication of documents in each of the three areas.

The results of a techno-economic model of distributed wind-hydrogen systems (WHS) located at each existing wind farm on the island of Ireland are presented in this paper. Hydrogen is produced by water electrolysis from wind energy and backed up by grid electricity, compressed before temporarily stored, then transported to the nearest injection location on the natural gas network. The model employs a novel correlation-based approach to select an optimum electrolyser capacity that generates a minimum levelised cost of hydrogen production (LCOH) for each WHS. Three scenarios of electrolyser operation are studied: (1) curtailed wind, (2) available wind, and (3) full capacity operations. Additionally, two sets of input parameters are used: (1) current and (2) future techno-economic parameters. Additionally, two electricity prices are considered: (1) low and (2) high prices. A closest facility algorithm in a geographic information system (GIS) package identifies the shortest routes from each WHS to its nearest injection point. By using current parameters, results show that small wind farms are not suitable to run electrolysers under available wind operation. They must be run at full capacity to achieve sufficiently low LCOH. At full capacity, the future average LCOH is 6–8 €/kg with total hydrogen production capacity of 49 kilotonnes per year, or equivalent to nearly 3% of Irish natural gas consumption. This potential will increase significantly due to the projected expansion of installed wind capacity in Ireland from 5 GW in 2020 to 10 GW in 2030.

Pulmonary arterial hypertension (PAH) is characterized by endothelial cell (EC) dysfunction. There are no data from living patients to inform whether differential gene expression of pulmonary artery ECs (PAECs) can discern disease subtypes, progression and pathogenesis. We aimed to further validate our previously described method to propagate ECs from right heart catheter (RHC) balloon tips and to perform additional PAEC phenotyping. We performed bulk RNA sequencing of PAECs from RHC balloons. Using unsupervised dimensionality reduction and clustering we compared transcriptional signatures from PAH to controls and other forms of pulmonary hypertension. Select PAEC samples underwent single cell and population growth characterization and anoikis quantification. Fifty-four specimens were analyzed from 49 subjects. The transcriptome appeared stable over limited passages. Six genes involved in sex steroid signaling, metabolism, and oncogenesis were significantly upregulated in PAH subjects as compared to controls. Genes regulating BMP and Wnt signaling, oxidative stress and cellular metabolism were differentially expressed in PAH subjects. Changes in gene expression tracked with clinical events in PAH subjects with serial samples over time. Functional assays demonstrated enhanced replication competency and anoikis resistance. Our findings recapitulate fundamental biological processes of PAH and provide new evidence of a cancer-like phenotype in ECs from the central vasculature of PAH patients. This “cell biopsy” method may provide insight into patient and lung EC heterogeneity to advance precision medicine approaches in PAH.

Context The impact of food and drinks on body fluid metabolism is of direct clinical relevance but current evidence remains fragmented. Aim Synthesise current evidence on the role of food and drinks in urine production. Methods Systematic review as per PRISMA guidelines using MEDLINE and EMBASE databases (completed October 2019). Studies reporting on the effect of food, food constituents, and drinks on urine production were included. Two authors performed an independent extraction of relevant articles using predetermined data sets and completed quality‐of‐study indicators. Results A total of 49 studies were included, of which 21 enroled human subjects, and 28 were clinically relevant animal studies (all of which utilised rodent models). The included studies were determined to be of variable quality. High dietary sodium, as well as wine, spirits, high‐caffeine coffee, and caffeinated energy drinks, increased urine production in human studies. Decreased urine production was associated with low dietary sodium and consumption of milk, orange juice, and high‐salt/high‐sugar drinks. In animal models, a variety of fruits, vegetables, herbs, spices, and honey were associated with increased urine production. Conclusion Current evidence suggests that although several types of food and drinks may impact body fluid metabolism, the quality of the data is variable. Urine production appears to be influenced by multiple factors including composition (ie, moisture, macronutrients, and electrolytes), metabolite load, and the presence of specific diuresis‐promoting substances (eg, caffeine, alcohol) and other bioactive phytochemicals. Future research is needed to support current evidence and the physiologic mechanisms underlying these findings.

To define the clinical characteristics of patients with variants in TCF20, we describe 27 patients, 26 of whom were identified via exome sequencing. We compare detailed clinical data with 17 previously reported patients. Patients were ascertained through molecular testing laboratories performing exome sequencing (and other testing) with orthogonal confirmation; collaborating referring clinicians provided detailed clinical information. The cohort of 27 patients all had novel variants, and ranged in age from 2 to 68 years. All had developmental delay/intellectual disability. Autism spectrum disorders/autistic features were reported in 69%, attention disorders or hyperactivity in 67%, craniofacial features (no recognizable facial gestalt) in 67%, structural brain anomalies in 24%, and seizures in 12%. Additional features affecting various organ systems were described in 93%. In a majority of patients, we did not observe previously reported findings of postnatal overgrowth or craniosynostosis, in comparison with earlier reports. We provide valuable data regarding the prognosis and clinical manifestations of patients with variants in TCF20.