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In this work, we study the global existence of solutions reaction-diffusion systems with control of mass on multiple domains. Some of these domains overlap, and as a result, an unknown defined on one subdomain can impact another unknown defined on a different domain that intersects with the first. The question addressed is related to the long standing question of global existence for reaction-diffusion systems with quasi-positive reaction vector fields that dissipate mass, in the setting of a single bounded spatial domain. The results extend recent work of the authors and others for systems on a single domain with L∞ diffusion and quasi-positive reaction vector fields that dissipate mass, in the setting of multiple domains.

I apply the Zhuangzi 莊子 to assess the contemporary value of personal autonomy. Focusing on two concepts, wuwei 無為 and you 遊, I clarify the “wandering ideal” in the Zhuangzi to challenge the ideal of autonomy as central to a well-lived life. Drawing on Sneddon’s persuasive recent account of autonomy, the Inner Chapters of the Zhuangzi , as well as recent secondary scholarship on the text, I show that the wandering ideal suggests a stark move away from the controlled and self-reflective life of the autonomous person. My goal is to draw on the Zhuangzi to contribute to dialogue on the ideal of autonomy, rather than to provide an innovative way of reading the Zhuangzi . I argue that both autonomy and wandering are higher-order ideals that can be applied to individual actions and to a person’s form of life, but at both levels, wandering and personal autonomy are in tension. The conclusion briefly reflects on the significance of the tension.

This book will empower experienced project managers and their business counterparts to understand and manage the risks of challenging business change projects. Providing principles and guidance, it shows project managers and owners how to guide projects home when mere excellence of technique or blind adherence to procedures would leave them at sea.

The development of the Internet of Things (IoT) technology and their integration in smart cities have changed the way we work and live, and enriched our society. However, IoT technologies present several challenges such as increases in energy consumption, and produces toxic pollution as well as E-waste in smart cities. Smart city applications must be environmentally-friendly, hence require a move towards green IoT. Green IoT leads to an eco-friendly environment, which is more sustainable for smart cities. Therefore, it is essential to address the techniques and strategies for reducing pollution hazards, traffic waste, resource usage, energy consumption, providing public safety, life quality, and sustaining the environment and cost management. This survey focuses on providing a comprehensive review of the techniques and strategies for making cities smarter, sustainable, and eco-friendly. Furthermore, the survey focuses on IoT and its capabilities to merge into aspects of potential to address the needs of smart cities. Finally, we discuss challenges and opportunities for future research in smart city applications.

The global existence and boundedness of solutions to quasi-linear reaction-diffusion systems are investigated. The system arises from compartmental models describing the spread of infectious diseases proposed in Viguerie et al. (Appl Math Lett 111:106617, 2021); Viguerie et al. (Comput Mech 66(5):1131–1152, 2020), where the diffusion rate is assumed to depend on the total population, leading to quasilinear diffusion with possible degeneracy. The mathematical analysis of this model has been addressed recently in Auricchio et al. (Math Methods Appl Sci 46:12529–12548, 2023) where it was essentially assumed that all sub-populations diffuse at the same rate, which yields a positive lower bound of the total population, thus removing the degeneracy. In this work, we remove this assumption completely and show the global existence and boundedness of solutions by exploiting a recently developed L p -energy method. Our approach is applicable to a larger class of systems and is sufficiently robust to allow model variants and different boundary conditions.

BackgroundThe preparation for critically ill children involves calculating drug and fluid volumes using the commonly taught WETFLAG (weight, energy, endotracheal tube, fluids, lorazepam, adrenaline, glucose) acronym. While smartphone applications (apps) are increasingly used for these calculations in clinical practice, limited studies have explored their accuracy and safety.AimTo assess the accuracy of three calculation methods for paediatric emergency drug doses and fluid volumes: a smartphone app, reference charts and traditional calculation methods. The secondary aims were to investigate the effect on the time taken and self-reported stress levels.MethodsA convenience sample of healthcare professionals from four hospitals contributed. Participants calculated drug and fluid doses for fictional patients using the three different methods. The method and case order were randomised centrally. The study recorded the number of errors made during the calculations, healthcare professionals’ self-reported stress levels on a scale of 0 (no stress) to 10 (maximum stress) and the time taken for each case. The app was developed at the direct request of the study team.ResultsNinety-six participants calculated values for six fictional cases, resulting in 576 calculations. Traditional calculation methods showed a statistically significant higher rate of error compared with the use of a smartphone app or reference charts (mean=1, 0, 0, respectively). The smartphone app outperformed both traditional calculation methods and reference charts for time taken and user-reported stress levels.ConclusionsTraditional methods of ‘WETFLAG’ drug and fluid calculations are associated with a statistically significant increased risk of error compared with the use of reference charts or smartphone app. The smartphone app proved significantly faster and less stressful to use compared with traditional calculation methods or reference charts.

Correspondence to Dr Emily Ball, Paediatric Emergency Department, University Hospital of Wales, Cardiff and Vale University Health Board, Cardiff, UK; emily.ball@wales.nhs.uk Background It is estimated that 1 in 300 people will experience anaphylaxis at some point1 with approximately 20–30 deaths per year in the UK from anaphylaxis.2 The treatment, investigation and follow-up of patients with anaphylaxis are frequently suboptimal, with approximately 50% of anaphylaxis episodes not treated appropriately with intramuscular epinephrine (adrenaline),3 despite previous guidance recommending epinephrine as first-line treatment. The treatment of anaphylaxis should be based on general life-support principles, such as call for help early, use the Airway, Breathing, Circulation, Disability, Exposure (ABCDE) approach to recognise and treat problems and treating the greatest threat to life first. BP, blood pressure; CPR, cardiopulmonary resuscitation; HR, heart rate; IO, intraosseous; IV, intravenous; SpO2, oxygen saturation; ABC, airway, breathing and circulation; ALS, advanced life support. Cardiorespiratory arrest during anaphylaxis Should cardiac arrest occur, absorption of epinephrine given by the intramuscular route will not be reliable and attempts to give it may interrupt the delivery of high-quality CPR.

This book will empower experienced project managers and their business counterparts to understand and manage the risks of challenging business change projects. It does this by focusing on setting projects up for success and emphasising the importance of understanding the business context. It shows project managers and owners how to guide difficult projects home when mere excellence of technique or blind adherence to procedures would leave them at sea.

Reading should be e ncouraged at all times, with an effort to promote books that are worthwhile and that enlarge the recruits' facility to encounter the world of letters and great national problems. . . {and are} designed to produce formidable benefits in moments of combat. - [...]the man most often referred to as the father of existentialism, Soren Kierkegaard, wrote about this, detailing life as a series of decisions often in difficult situations. If the Cubans were reading and studying For Whom the Bell Tolls in the Sierra Maestra, they would find a good role model for indoctrination with Robert Jordan, who admires his leader, Golz and who, in turn, gains the respect of Pablo's band. [...]every moment provides an opportunity to intuitively draw on a vast reservoir of experience and understanding to create a reality from a range of possibilities.