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Cervical spine fractures are associated with high mortality in elderly patients. This study aims to identify patient-related and in-hospital factors contributing to this mortality. A 3-year retrospective study of 235 patients aged 65+ presenting with cervical spine fractures was performed. Age cohorts were 65–74, 75–84, and 85+ years. Mortality was measured at 30, 90, 180 and 365-days post-discharge. Mortality was 11 ​%, 15 ​%, 19 ​%, and 22 ​% at 30-, 90-, 180- and 365-days respectively. Surgery and fracture pattern was not associated with mortality (p ​= ​0.37; p ​= ​0.28). Charlson Comorbidity Index (p ​< ​0.001; hazard ratio [HR] ​= ​1.3), functional dependency (p ​< ​0.001; HR ​= ​2.5) and delirium (p ​< ​0.001; HR ​= ​8.9) were associated with mortality between 0 and 365 days post-discharge. Mortality in cervical spine fractures is associated with CCI and delirium, but not associated with operative management or fracture pattern. This suggests the need for careful consideration in patient selection for cervical spine procedures and aggressive inpatient delirium management. •Mortality risk increases with many different chronic medical issues.•Surgery did not significantly change mortality rate in our study population.•Mortality is significantly increased with the diagnosis of inpatient delirium.

PurposeThe purpose of this study was to compare the rates of adjacent segment degeneration (ASD), sagittal alignment parameters, and patient-reported outcomes in patients who underwent multi-level versus single-level anterior cervical discectomy and fusion (ACDF).MethodsA retrospective cohort analysis was performed on consecutive patients who underwent an ACDF. Pre- and post-operative radiographic assessment included ASD, change in C2–C7 lordosis, T1 angle, levels fused, sagittal vertical axis (SVA), fusion mass lordosis, proximal and distal adjacent segment lordosis. Patient-reported outcomes were obtained.ResultsOf the 404 that underwent an ACDF with a minimum of 6 months of follow-up (average 28 months), there was no significant difference in the rate of radiographic ASD overall (p = 0.479) or in the proximal or distal adjacent segments on multivariate analysis. Secondarily, the multi-level fusions appear to restore significantly greater amounts of lordosis compared to single-level procedures (p < 0.001) and are able to maintain the corrected cervical lordosis and fusion segment lordosis over time. From the immediate post-operative period to final follow-up, the single-level ACDFs show continuing lordosis improvement (p = 0.005) that is significantly greater than that of the multi-level constructs. There were no significant differences between pre-operative, post-operative, or change in patient-reported outcomes.ConclusionsTwo years following an ACDF, patients who underwent multi-level fusions appear to restore significantly greater amounts of lordosis compared to single-level procedures, while single-level ACDFs show significantly greater amounts of lordosis improvement over time. Multi-level procedures may not be at a significantly greater risk of developing early radiographic evidence of ASD compared to single-level procedure.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material.