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1. The ability to forage and return home is essential to the success of bees as both foragers and pollinators. Pesticide exposure may cause behavioural changes that interfere with these processes, with consequences for colony persistence and delivery of pollination services. 2. We investigated the impact of chronic exposure (5-43 days) to field-realistic levels of a neonicotinoid insecticide (2·4 ppb thiamethoxam) on foraging ability, homing success and colony size using radio frequency identification (RFID) technology in free-flying bumblebee colonies. 3. Individual foragers from pesticide-exposed colonies carried out longer foraging bouts than untreated controls (68 vs. 55 min). Pesticide-exposed bees also brought back pollen less frequently than controls indicating reduced foraging performance. 4. A higher proportion of bees from pesticide-exposed colonies returned when released 1 km from their nests; this is potentially related to increased orientation experience during longer foraging bouts. We measured no impact of pesticide exposure on homing ability for bees released from 2 km, or when data were analysed overall. 5. Despite a trend for control colonies to produce more new workers earlier, we found no overall impacts of pesticide exposure on whole colony size. 6. Synthesis and applications. This study shows that field-realistic neonicotinoid exposure can have impacts on both foraging ability and homing success of bumblebees, with implications for the success of bumblebee colonies in agricultural landscapes and their ability to deliver crucial pollination services. Pesticide risk assessments should include bee species other than honeybees and assess a range of behaviours to elucidate the impact of sublethal effects. This has relevance for reviews of neonicotinoid risk assessment and usage policy world-wide.

The ecological success of social insects is frequently ascribed to improvements in task performance due to division of labour amongst workers. While much research has focused on improvements associated with lifetime task specialization, members of colonies can specialize on a given task over shorter time periods. Eusocial bees in particular must collect pollen and nectar rewards to survive, but most workers appear to mix collection of both rewards over their lifetimes. We asked whether bumblebees specialize over timescales shorter than their lifetime. We also explored factors that govern such patterns, and asked whether reward specialists made more foraging bouts than generalists. In particular, we described antennal morphology and size of all foragers in a single colony and related these factors to each forager’s complete foraging history, obtained using radio frequency identification (RFID). Only a small proportion of foragers were lifetime specialists; nevertheless, >50% of foragers specialized daily on a given reward. Contrary to expectations, daily and lifetime reward specialists were not better foragers (being neither larger nor making more bouts); larger bees with more antennal olfactory sensilla made more bouts, but were not more specialized. We discuss causes and functions of short and long-term patterns of specialization for bumblebee colonies.

Exoplanet systems with multiple planets in mean motion resonances have often been hailed as a signpost of disk driven migration. Resonant chains like Kepler-223 and Kepler-80 consist of a trio of planets with the three-body resonant angle librating and/or with a two-body resonant angle librating for each pair. Here we investigate whether close-in super-Earths and mini-Neptunes forming in situ can lock into resonant chains due to dissipation from a depleted gas disk. We simulate the giant impact phase of planet formation, including eccentricity damping from a gaseous disk, followed by subsequent dynamical evolution over tens of millions of years. In a fraction of simulated systems, we find that planets naturally lock into resonant chains. These planets achieve a chain of near-integer period ratios during the gas disk stage, experience eccentricity damping that captures them into resonance, stay in resonance as the gas disk dissipates, and avoid subsequent giant impacts, eccentricity excitation, and chaotic diffusion that would dislodge the planets from resonance. Disk conditions that enable planets to complete their formation during the gas disk stage enable those planets to achieve tight period ratios <= 2 and, if they happen to be near integer period ratios, lock into resonance. Using the weighting of different disk conditions deduced by MacDonald et al. (2020) and forward modeling Kepler selection effects, we find that our simulations of in situ formation via oligarchic growth lead to a rate of observable trios with integer period ratios and librating resonant angles comparable to observed Kepler systems.

While many observed debris disks are thought to have gaps suggestive of the presence of planets, direct imaging surveys do not find many high mass planets in these systems. We investigate if divergent migration is a viable mechanism for forming gaps in young debris disks with planets of low enough mass to currently elude detection. We perform numerical integrations of planet pairs embedded in planetesimal disks to assess the conditions for which divergent, planetesimal-driven migration occurs and gaps form within the disk. Gap widths and the migration rate of planets within a pair depend on both disk mass and the degree to which the planets share disk material. We find that planet pairs with planets more massive than Neptune can produce gaps with widths similar to their orbit distance within 10 Myr at orbit separations probed by direct imaging campaigns. Pairs of migrating super-Earths likely cannot form observable gaps on the same time and distance scales, however. Inferring the responsible planet masses from these gaps while neglecting migration could overestimate the mass of planets by more than an order of magnitude.

Super-Earths and mini-Neptunes exhibit great diversity in their compositional and orbital properties. Their bulk densities span a large range, from those dense enough to be purely rocky to those needing a substantial contribution from volatiles to their volumes. Their orbital configurations range from compact, circular multi-transiting systems like Kepler-11 to systems like our Solar System's terrestrial planets with wider spacings and modest but significant eccentricities and mutual inclinations. Here we investigate whether a continuum of formation conditions resulting from variation in the amount of solids available in the inner disk can account for the diversity of orbital and compositional properties observed for super Earths, including the apparent dichotomy between single transiting and multiple transiting system. We simulate in situ formation of super-Earths via giant impacts and compare to the observed Kepler sample. We find that intrinsic variations among disks in the amount of solids available for in situ formation can account for the orbital and compositional diversity observed among Kepler's transiting planets. Our simulations can account for the planets' distributions of orbital period ratios, transit duration ratios, and transit multiplicity; higher eccentricities for single than multi transiting planets; smaller eccentricities for larger planets; scatter in the mass-radius relation, including lower densities for planets with masses measured with TTVs than RVs; and similarity in planets' sizes and spacings within each system. Our findings support the theory that variation among super-Earth and mini-Neptune properties is primarily locked in by different in situ formation conditions, rather than arising stochastically through subsequent evolution.

In the coming years, high contrast imaging surveys are expected to reveal the characteristics of the population of wide-orbit, massive, exoplanets. To date, a handful of wide planetary mass companions are known, but only one such multi-planet system has been discovered: HR8799. For low mass planetary systems, multi-planet interactions play an important role in setting system architecture. In this paper, we explore the stability of these high mass, multi-planet systems. While empirical relationships exist that predict how system stability scales with planet spacing at low masses, we show that extrapolating to super-Jupiter masses can lead to up to an order of magnitude overestimate of stability for massive, tightly packed systems. We show that at both low and high planet masses, overlapping mean motion resonances trigger chaotic orbital evolution, which leads to system instability. We attribute some of the difference in behavior as a function of mass to the increasing importance of second order resonances at high planet-star mass ratios. We use our tailored high mass planet results to estimate the maximum number of planets that might reside in double component debris disk systems, whose gaps may indicate the presence of massive bodies.

Antarctic climate trends observed in the satellite record are compared with a two hundred year paleoclimate record. The satellite record is found to be too short to attribute changes to anthropogenic forcing, with natural variability overwhelming the forced signal. Understanding the causes of recent climatic trends and variability in the high-latitude Southern Hemisphere is hampered by a short instrumental record. Here, we analyse recent atmosphere, surface ocean and sea-ice observations in this region and assess their trends in the context of palaeoclimate records and climate model simulations. Over the 36-year satellite era, significant linear trends in annual mean sea-ice extent, surface temperature and sea-level pressure are superimposed on large interannual to decadal variability. Most observed trends, however, are not unusual when compared with Antarctic palaeoclimate records of the past two centuries. With the exception of the positive trend in the Southern Annular Mode, climate model simulations that include anthropogenic forcing are not compatible with the observed trends. This suggests that natural variability overwhelms the forced response in the observations, but the models may not fully represent this natural variability or may overestimate the magnitude of the forced response.

Maternal asthma is associated with increased rates of neonatal lung disease, and fetuses from asthmatic ewes have fewer surfactant‐producing cells and lower surfactant‐protein B gene (SFTPB) expression than controls. Antenatal betamethasone increases lung surfactant production in preterm babies, and we therefore tested this therapy in experimental maternal asthma. Ewes were sensitised to house dust mite allergen, and an asthmatic phenotype induced by fortnightly allergen lung challenges; controls received saline. Pregnant asthmatic ewes were randomised to receive antenatal saline (asthma) or 12 mg intramuscular betamethasone (asthma+beta) at 138 and 139 days of gestation (term = 150 days). Lambs were delivered by Caesarean section at 140 days of gestation and ventilated for 45 min before tissue collection. Lung function and structure were similar in control lambs (n = 16, 11 ewes) and lambs from asthma ewes (n = 14, 9 ewes). Dynamic lung compliance was higher in lambs from asthma+beta ewes (n = 12, 8 ewes) compared to those from controls (P = 0.003) or asthma ewes (P = 0.008). Lung expression of surfactant protein genes SFTPA (P = 0.048) and SFTPB (P < 0.001), but not SFTPC (P = 0.177) or SFTPD (P = 0.285), was higher in lambs from asthma+beta than those from asthma ewes. Female lambs had higher tidal volume (P = 0.007), dynamic lung compliance (P < 0.001), and SFTPA (P = 0.037) and SFTPB gene expression (P = 0.030) than males. These data suggest that betamethasone stimulates lung maturation and function of near‐term neonates, even in the absence of impairment by maternal asthma. What is the central question of this study? Does antenatal betamethasone before near‐term delivery mitigate the increased risk of neonatal lung disease in a sheep model of maternal asthma? What is the main finding and its importance? Maternal asthma did not impair neonatal lung function or reduce surfactant gene expression, likely reflecting a mild maternal and fetal phenotype in this cohort. Nevertheless, antenatal maternal betamethasone treatment in asthmatic pregnancies increased dynamic lung compliance and surfactant protein A and B mRNA expression in newborn lambs. These data suggest potential benefits of betamethasone on lung maturation when mothers have asthma.

Gastrointestinal disease caused by the apicomplexan parasite Cryptosporidium parvum is one of the most important diseases of young ruminant livestock, particularly neonatal calves. Infected animals may suffer from profuse watery diarrhoea, dehydration and in severe cases death can occur. At present, effective therapeutic and preventative measures are not available and a better understanding of the host–pathogen interactions is required. Cryptosporidium parvum is also an important zoonotic pathogen causing severe disease in people, with young children being particularly vulnerable. Our knowledge of the immune responses induced by Cryptosporidium parasites in clinically relevant hosts is very limited. This review discusses the impact of bovine cryptosporidiosis and describes how a thorough understanding of the host–pathogen interactions may help to identify novel prevention and control strategies.

Over half the world’s population is at risk for viruses transmitted by Aedes mosquitoes, such as dengue and Zika. The primary vector, Aedes aegypti, thrives in urban environments. Despite decades of effort, cases and geographic range of Aedes-borne viruses (ABVs) continue to expand. Rigorously proven vector control interventions that measure protective efficacy against ABV diseases are limited to Wolbachia in a single trial in Indonesia and do not include any chemical intervention. Spatial repellents, a new option for efficient deployment, are designed to decrease human exposure to ABVs by releasing active ingredients into the air that disrupt mosquito–human contact. A parallel, cluster-randomized controlled trial was conducted in Iquitos, Peru, to quantify the impact of a transfluthrin-based spatial repellent on human ABV infection. From 2,907 households across 26 clusters (13 per arm), 1,578 participants were assessed for seroconversion (primary endpoint) by survival analysis. Incidence of acute disease was calculated among 16,683 participants (secondary endpoint). Adult mosquito collections were conducted to compare Ae. aegypti abundance, blood-fed rate, and parity status through mixed-effect difference-in-difference analyses. The spatial repellent significantly reduced ABV infection by 34.1% (one-sided 95% CI lower limit, 6.9%; onesided P value = 0.0236, z = 1.98). Aedes aegypti abundance and blood-fed rates were significantly reduced by 28.6 (95% CI 24.1%, ∞); z = 29.11) and 12.4% (95% CI 4.2%, ∞); z = 22.43), respectively. Our trial provides conclusive statistical evidence from an appropriately powered, preplanned cluster-randomized controlled clinical trial of the impact of a chemical intervention, in this case a spatial repellent, to reduce the risk of ABV transmission compared to a placebo.