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Gastroschisis and omphalocele are the most frequent congenital abdominal wall defects Described in the literature since the first century. It is occurring in 1 in 4000 live births. ETHICON PHYSIOMESH™ is Flexible Composite Mesh physiologically designed for repair of hernias and fascial defects. The mesh product is composed non absorbable, macro porous polypropalene mesh laminated between two polyglecaprone-25 films. An undyed polydioxanone film provides the boned between the polyglecaprone-25 film and polypropylene mesh. Patients with large congenital abdominal wall defects (>5cm) in omaphalocel while excess protrusion of the inta abdominal viscera in gastroschisis regard less the defect size were subjected to clinical examination and routine laboratory investigations. Between March 2008 to April 2013, 21 patients presented with abdominal wall defect, six patients were excluded from analysis due to the presence of other lethal anomalies and complications not related to the surgical treatment. Diagnoses in excluded patients included Great vessels anomalies (2), central nerves system male formation (1), intestinal perforations at the time of birth (1), associated coloacal anomalies (1), mid gut atresia (1). Fifteen cases were taken up for closure within 24 - 72 hours of presentation, 8 patient went primary repair with out mesh,7cases get primary repair with physiomesh. The use of physiomesh in the repair of the neonatal major abdominal wall defect is feasible less complication with acceptable coast farther study of more number of case and long term follow up.

Background Chronic obstructive pulmonary disease (COPD) is a significant cause of death. Cardiovascular disease is a significant cause of morbidity and mortality in COPD. Aim We used echocardiography to evaluate cardiac function in patients with COPD and correlated echocardiographic findings with COPD severity. Patients and methods We performed a prospective cross-sectional study on 60 patients with stable COPD who presented to the Abbasia Chest Hospital during the period from November 2016 till August 2017. Spirometry was performed for all participants using American and European Thoracic Society (2005) recommendations. They were classified according to GOLD guidelines (2017) and evaluated by two-dimensional Doppler echocardiography according to American and European Association of Echocardiography ASE recommendations. Results Echocardiographic examination of left ventricular functions revealed no cases of left ventricular systolic dysfunction, but left ventricular diastolic dysfunction was found in ~25%. Right ventricle dilatation was found in ~18% of the patients. Tricuspid regurge was seen in ~75%, with variable grades from mild to severe. Pulmonary hypertension (PH) was found in ~40% of the patients. It was more prevalent in patients with severe and very severe disease. Correlation between echocardiographic findings and severity of COPD revealed significant positive correlation only with right ventricle size, tricuspid regurgitation, and PH. Conclusion Left ventricular diastolic dysfunction appears to be frequent in patients with COPD, but it is not related to the disease severity. Abnormal right heart changes could be expected. Presence of PH has a linear relationship with COPD severity.

The content of vitamin C (ascorbic acid) in different samples of fruits and vegetables was determined by spectrophotometric method. This method relies on its ability to reduce permanganate colors at (530 nm). Where samples were collected from the local market in the city of Marg. A linear concentration range of ascorbic acid buffer solutions was obtained between (0.25-32) μg/ml with a correlation coefficient (R2 = 0.9666) and the ascorbic acid content of fresh fruit was found between 0.25 and 1405 mg/100g. As well as 0.280 and 475 mg/ 100 g of fresh vegetables. The results of the study gave a large variation in the vitamin C content between the fruit samples, which could be due to the level of ripeness of the fruit or due to the reduction of the permanganate ion by the sugars.