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Ever since the Renaissance speaking about paintings has been a fundamental approach for beholders, especially experts. However, it is unclear whether and how speaking about art modifies the way we look at it and this was not yet empirically tested. The present study investigated to the best of our knowledge for the first time in what way speaking modifies the patterns of fixations and gaze movements while looking at paintings. Ninety nine university students looked at four paintings selected to cover different art historical typologies for periods of 15 minutes each while gaze movement data were recorded. After 10 minutes, the participants of the experimental group were asked open questions about the painting. Speaking dramatically reduced the duration of fixations and painting area covered by fixations while at the same time increasing the frequencies of fixations, gaze length and the amount of repeated transitions between fixation clusters. These results suggest that the production of texts as well-organised sequences of information, structures the gazes of art beholders by making them quicker, more focused and better connected.

Long-term torpor is an adaptive strategy that allows animals to survive harsh winter conditions. However, the impact that prolonged torpor has on cognitive function is poorly understood. Hibernation causes reduced synaptic activity and experiments with mammals reveal that this can have adverse effects on memories formed prior to hibernation. The impact of brumation, the winter dormancy that is observed in ectotherms, on memory remains unknown. The aim of this study was to examine whether an amphibian, the fire salamander ( Salamandra salamandra ), was able to retain learned spatial information after a period of brumation. Twelve fire salamanders were trained to make a simple spatial discrimination using a T-maze. All subjects learned the initial task. Upon reaching criterion, half of the subjects were placed into brumation for 100 days while the other half served as controls and were maintained under normal conditions. A post-brumation memory retention test revealed that animals from both conditions retained the learned response. Control tests showed that they solved the task using learned information and not olfactory cues. This finding contrasts with much of the mammalian research and suggests that the processes involved in prolonged torpor may have a fundamentally different impact on memory in mammals and amphibians.

To recognize that a picture is a representation of a real-life object is a cognitively demanding task. It requires an organism to mentally represent the concrete object (the picture) and abstract its relation to the item that it represents. This form of representational insight has been shown in a small number of mammal and bird species. However, it has not previously been studied in reptiles. This study examined picture–object recognition in the red-footed tortoise (Chelonoidis carbonaria). In Experiment 1, five red-footed tortoises were trained to distinguish between food and non-food objects using a two-alternative forced choice procedure. After reaching criterion, they were presented with test trials in which the real objects were replaced with color photographs of those objects. There was no difference in performance between training and test trials, suggesting that the tortoises did see some correspondence between the real object and its photographic representation. Experiment 2 examined the nature of this correspondence by presenting the tortoises with a choice between the real food object and a photograph of it. The findings revealed that the tortoises confused the photograph with the real-life object. This suggests that they process real items and photographic representations of these items in the same way and, in this context, do not exhibit representational insight.

Purpose To elicit patient experiences of weight management discussions with providers and provide recommendations for future weight-related discussions. Methods 1000 patients who recently saw their provider for non-weight specific appointments were mailed measures of demographics, self-reported height and weight, activity level, adherence, perceptions of and recommendations for weight-related discussions, and internalized weight bias. This study was primarily descriptive and utilized a mixed method design including collection of quantitative and qualitative data. Results 242 patients responded (24 % response rate); 32.4 % overweight ( N  = 72), 41.9 % obese ( N  = 93). 47 % of overweight and 71 % of obese patients recalled that their provider discussed weight; 92 % were motivated to follow recommendations and 89 % felt confident doing so. Most patients (75 %) would like their provider to be “very direct/straightforward” when discussing weight, and 52 % would be “not at all offended” if they were diagnosed as “overweight/obese.” Most patients (63 %) reported being “extremely comfortable” discussing weight with providers. Patients with higher BMI had higher levels of internalized weight bias ( p  < .001) and wanted their provider to “discuss weight sensitively” ( p  < .05). Conclusion This study suggests that patients have important preferences that providers should be mindful of when discussing weight. While these discussions can be challenging, most patients report that they would be comfortable having these conversations directly and most would have enhanced motivation and confidence following these conversations. Communicating about weight is needed and desired by patients; doing so sensitively with those at higher weight is essential.

Extracellular matrix (ECM) deposition after central nervous system (CNS) injury leads to inhibitory scarring in humans and other mammals, whereas it facilitates axon regeneration in the zebrafish. However, the molecular basis of these different fates is not understood. Here, we identify small leucine-rich proteoglycans (SLRPs) as a contributing factor to regeneration failure in mammals. We demonstrate that the SLRPs chondroadherin, fibromodulin, lumican, and prolargin are enriched in rodent and human but not zebrafish CNS lesions. Targeting SLRPs to the zebrafish injury ECM inhibits axon regeneration and functional recovery. Mechanistically, we find that SLRPs confer mechano-structural properties to the lesion environment that are adverse to axon growth. Our study reveals SLRPs as inhibitory ECM factors that impair axon regeneration by modifying tissue mechanics and structure, and identifies their enrichment as a feature of human brain and spinal cord lesions. These findings imply that SLRPs may be targets for therapeutic strategies to promote CNS regeneration. The mechanical properties of central nervous system (CNS) scar tissue are considered to contribute to axon regeneration failure. Here, the authors identify members of the small leucine-rich proteoglycan family as modulators of the inhibitory viscoelastic response of CNS lesions.

Although director Angela Bassett has played both Tina Turner and Jackson family matriarch Katherine in musical biopics, there's a surprisingly amateur feel to her made-for-TV take on Whitney Houston's rise to fame. Yaya DaCosta stars as the troubled ingenue-turned-pop megastar, whose substance abuse and difficult relationship with Bobby Brown (Arlen Escarpeta) are charted in excruciating detail. Vocals from Deborah Cox - like Whitney, a protege of Clive Davis - are a highlight of this reductive, weirdly voyeuristic watch. HJD Giggles and family bonding abound as the series draws to a close. Young Garfy's off to a festival, while his mum and her posse are going to a spa. \"What are you having done first, your face ironed or your knockers pleated?\" quips Sharon as Dorien uses the minibreak as a man-hunting ground. Meanwhile, Tracey gets the results of her cancer tests, which makes for some warm moments. Worth watching just for the look on Lesley Joseph's face when she has to deliver Dorien's more camp lines involving \"erotic milestones\". HV