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"Mulqueen, Michael"
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Re-evaluating Irish national security policy
On the afternoon of September 11 2001 the Irish Prime Minister (Taoiseach), Bertie Ahern ordered the ‘heads of the security services of key government departments’ to undertake a complete re-evaluation of measures to protect the state from attack. Hence, underway within hours of the 9/11 outrage in the United States was potentially the most far-reaching review of Irish national security in decades. This book, the first major academic investigation of Irish national security policy as it has operated since 9/11, provides a theoretically informed analysis of that re-evaluation and the decisions which have been taken as a consequence of it up until September 2008. In so doing it draws on unprecedented access to Ireland’s police, security and intelligence agencies; over twenty senior personnel agreed to be interviewed.Theoretically the author demonstrates the utility to the analysis of national security policy of three conceptual models of historical institutionalism, governmental politics and threat evaluation. The text is of interest to scholars of Security Studies, International Relations and Politics, as well as state and NGO personnel, journalists and general readers.
eBook
Re-evaluating Irish national security policy
The first major academic investigation of Irish national security policy as it has operated since 9/11. It draws on unprecedented access to Ireland's security and intelligence agencies; over twenty senior personnel were interviewed.
eBook
The Role of Endogenous Interleukin-12 in Resistance to Murine Cytomegalovirus (MCMV) Infection and a Novel Action for Endogenous IL-12 p40
Biologically active interleukin-12 (IL-12), comprising a 40 kDa subunit (p40) covalently linked to a 35 kDa subunit (p35), is produced in response to a range of infectious stimuli. Here, we demonstrate that mice deficient in either IL-12 p40 (p40-/-) or IL-12 p35 (p35-/-) are susceptible to murine cytomegalovirus (MCMV) infection in terms of survival (Balb/c p35-/-) and viral clearance (Balb/c p35-/- and Balb/c p40-/-), and this susceptibility may be correlated to a deficiency in serum interferon-γ (IFN-γ) levels. These data support a role for endogenous IL-12 in controlling MCMV infection. The IL-12 p40 subunit is produced in excess of IL-12 p35, and to date the function of the excess endogenous p40 has been assumed to be one of IL-12 antagonism, as demonstrated by experiments with exogenous p40 both in vivo and in vitro. We show that Balb/c p35-/- alone are significantly compromised in survival of a sublethal infection and in clearance of virus from the spleen. These mice produce a very early IFN-γ spike (8 h after infection) and an aberrant tumor necrosis factor-α (TNF-α) spike (day 2 after infection). MCMV infection has revealed an altered Balb/c p35-/- phenotype compared with Balb/c p40-/-, and this indicates that endogenous p40 may have an activity independent of and additional to IL-12 antagonism in vivo.
Journal Article
The Irish national security apparatus
To engage with the investigation presented in this study knowledge of the principal organisations at the frontline of proactive security is necessary. So here, general characteristics of these organisations are set out together with a brief analysis of how the State coped with two previous crises, the Emergency of 1939–45 and the Northern Ireland Troubles since 1969. Doing so will also help contextualise subsequent analysis. For example, the discussion on Northern Ireland will consider, among other issues, the use of law against subversion, what on-island terrorism meant for the Defence Forces’ operational posture and the challenges which border security
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