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\"In 1919, as civil and social unrest grips the country, there is a little corner of America, a place called Harlem where something special is stirring. Here, the New Negro is rising and Black pride is evident everywhere...in music, theatre, fashion and the arts. And there on stage in the center of this renaissance is Jessie Redmon Fauset, the new literary editor of the preeminent Negro magazine The Crisis. W.E.B. Du Bois, the founder and editor of The Crisis, has charged her with discovering young writers whose words will change the world. Jessie attacks the challenge with fervor, quickly finding sixteen-year-old Countee Cullen, seventeen-year-old Langston Hughes, and Nella Larsen, who becomes one of her best friends. Under Jessie's leadership, The Crisis thrives, the writers become notable and magazine subscriptions soar. Every Negro writer in the country wants their work published in the magazine now known for its groundbreaking poetry and short stories. Jessie's rising star is shining bright....but her relationship with W.E.B. could jeopardize all that she's built. The man, considered by most to be the leader of Black America, is not only Jessie's boss, he's her lover. And neither his wife, nor their fourteen-year-age difference can keep the two apart. Their torrid and tumultuous affair is complicated by a secret desire that Jessie harbors - to someday, herself, become the editor of the magazine, a position that only W.E.B. Du Bois has held. In the face of overwhelming sexism and racism, Jessie must balance her drive with her desires. However, as she strives to preserve her legacy, she'll discover the high cost of her unparalleled success\"-- Provided by publisher.

The Global Burden of Disease Study (GBD) began 30 years ago with the goal of providing timely, valid and relevant assessments of critical health outcomes. Over this period, the GBD has become progressively more granular. The latest iteration provides assessments of thousands of outcomes for diseases, injuries and risk factors in more than 200 countries and territories and at the subnational level in more than 20 countries. The GBD is now produced by an active collaboration of over 8,000 scientists and analysts from more than 150 countries. With each GBD iteration, the data, data processing and methods used for data synthesis have evolved, with the goal of enhancing transparency and comparability of measurements and communicating various sources of uncertainty. The GBD has many limitations, but it remains a dynamic, iterative and rigorous attempt to provide meaningful health measurement to a wide range of stakeholders. This Perspective reflects on the past, present and future of the dynamic, expanding public health endeavor that is the Global Burden of Disease Study.

\"A novel about the extraordinary partnership between First Lady Eleanor Roosevelt and civil rights activist Mary McLeod Bethune--an unlikely friendship that changed the world, from the New York Times bestselling authors of the Good Morning America Book Club pick The Personal Librarian. The daughter of formerly enslaved parents, Mary McLeod Bethune refuses to back down as white supremacists attempt to thwart her work. She marches on as an activist and an educator, and as her reputation grows she becomes a celebrity, revered by titans of business and recognized by U.S. Presidents. Eleanor Roosevelt herself is awestruck and eager to make her acquaintance. Initially drawn together because of their shared belief in women's rights and the power of education, Mary and Eleanor become fast friends confiding their secrets, hopes and dreams-and holding each other's hands through personal and professional strife. When Franklin Delano Roosevelt is elected president, the two women begin to collaborate more closely, particularly as Eleanor moves toward her own agenda separate from FDR, a consequence of the devastating discovery of her husband's secret love affair. Eleanor becomes a controversial First Lady for her outspokenness, particularly on civil rights. And when she receives threats because of her strong ties to Mary, it only fuels the women's desire to fight together for justice and equality. This is the story of two different, yet equally formidable, passionate, and committed women, and the way in which their singular friendship helped form the foundation for the modern civil rights movement\"-- Provided by publisher.

The Vaccine-Hesitant MomentThe proliferation of vaccine misinformation and its use for political purposes are placing a large number of people at risk in the Covid-19 pandemic and allowing the pandemic to continue.

\"\"Fat\". In contemporary society the word never fails to elicit powerful emotions, especially as it relates to bodily health and appearance. But fat is a noun as well as an adjective and has a cultural life outside of its relationship with the human body. By focusing on the complex physical and experiential dimensions of this problematic substance, Fat: Culture and Materiality breaks new ground in the study of the relationship between culture and the material world. With contributions from well-respected international scholars, this innovative and interdisciplinary collection will appeal to a wide range of readers interested in fat and its relationship to culture, materiality and lived experience. The volume addresses the role of fats in a variety of cultural settings. Topics include the politics of Palestinian olive oil; the allure of pig fat in heritage pork; the material sources of fat stereotypes in classical and biblical texts; the use of harvested fat in aesthetic surgery; and the status of fat in the self-narratives of anorexics\"-- Provided by publisher.

The burden that disease places on societies around the world is complex and changing as communicable diseases are replaced by noncommunicable diseases. This article summarizes these changes and the current burden. It is difficult to deliver effective and high-quality care to patients without knowing their diagnoses; likewise, for health systems to be effective, it is necessary to understand the key challenges in efforts to improve population health and how these challenges are changing. Before the early 1990s, there was no comprehensive and internally consistent source of information on the global burden of diseases, injuries, and risk factors. To close this gap, the World Bank and the World Health Organization launched the Global Burden of Disease (GBD) Study in 1991. 1 Although assessments of selected diseases, injuries, and risk factors in selected populations . . .

Stunning photographs of Soviet Metro Stations from across the former states of the USSR and Russia itself, many of which have never previously been documented.

We used data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2010 (GBD 2010) to estimate the burden of disease attributable to mental and substance use disorders in terms of disability-adjusted life years (DALYs), years of life lost to premature mortality (YLLs), and years lived with disability (YLDs). For each of the 20 mental and substance use disorders included in GBD 2010, we systematically reviewed epidemiological data and used a Bayesian meta-regression tool, DisMod-MR, to model prevalence by age, sex, country, region, and year. We obtained disability weights from representative community surveys and an internet-based survey to calculate YLDs. We calculated premature mortality as YLLs from cause of death estimates for 1980–2010 for 20 age groups, both sexes, and 187 countries. We derived DALYs from the sum of YLDs and YLLs. We adjusted burden estimates for comorbidity and present them with 95% uncertainty intervals. In 2010, mental and substance use disorders accounted for 183·9 million DALYs (95% UI 153·5 million–216·7 million), or 7·4% (6·2–8·6) of all DALYs worldwide. Such disorders accounted for 8·6 million YLLs (6·5 million–12·1 million; 0·5% [0·4–0·7] of all YLLs) and 175·3 million YLDs (144·5 million–207·8 million; 22·9% [18·6–27·2] of all YLDs). Mental and substance use disorders were the leading cause of YLDs worldwide. Depressive disorders accounted for 40·5% (31·7–49·2) of DALYs caused by mental and substance use disorders, with anxiety disorders accounting for 14·6% (11·2–18·4), illicit drug use disorders for 10·9% (8·9–13·2), alcohol use disorders for 9·6% (7·7–11·8), schizophrenia for 7·4% (5·0–9·8), bipolar disorder for 7·0% (4·4–10·3), pervasive developmental disorders for 4·2% (3·2–5·3), childhood behavioural disorders for 3·4% (2·2–4·7), and eating disorders for 1·2% (0·9–1·5). DALYs varied by age and sex, with the highest proportion of total DALYs occurring in people aged 10–29 years. The burden of mental and substance use disorders increased by 37·6% between 1990 and 2010, which for most disorders was driven by population growth and ageing. Despite the apparently small contribution of YLLs—with deaths in people with mental disorders coded to the physical cause of death and suicide coded to the category of injuries under self-harm—our findings show the striking and growing challenge that these disorders pose for health systems in developed and developing regions. In view of the magnitude of their contribution, improvement in population health is only possible if countries make the prevention and treatment of mental and substance use disorders a public health priority. Queensland Department of Health, National Health and Medical Research Council of Australia, National Drug and Alcohol Research Centre-University of New South Wales, Bill & Melinda Gates Foundation, University of Toronto, Technische Universität, Ontario Ministry of Health and Long Term Care, and the US National Institute of Alcohol Abuse and Alcoholism.