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The pharmacy profession has significantly changed over the years. Pharmacy students' perceptions of their coursework and future career aspirations may vary in relation to gender. The present study explored the motivations of pharmacy students to enter pharmacy school, their satisfaction with the academic program, future plans after graduation, and perceptions about the pharmacy profession in relation to gender. Data were collected using a cross-sectional descriptive validated questionnaire built by the research team. The study was conducted at twelve public and private universities offering pharmacy programs. In total, 918 pharmacy students have completed the online questionnaire, with a 98% response rate. Most participants reported that family encouragement was a motive to enter pharmacy school. The results of the Chi-Squared Test indicated a significant difference between female and male participants with respect to the following motives: High school grades (p = 0.009), being good at science (p = 0.013), working with patients(p = 0.024), professional status (p = 0.014), working in a family business (p = 0.001) and job opportunities (p = 0.001). The majority of male participants and female participants perceived pharmacy jobs as prestigious jobs. In addition, male and female students believed that it was a profession with well-paid jobs. Females were significantly more motivated by their high school degrees, goodness at science, working with patients, and professional status to enter pharmacy school. Pharmacy students are satisfied enough with the academic program. Male and female pharmacists have different career aspirations in the pharmaceutical sectors. It is recommended that students be educated about career planning to help them accomplish their goals. Future research could benefit from longitudinal studies to explore changes in pharmacy students' motivations, satisfaction, and career aspirations over time.

The literature on nutrition support therapy prescribing practices by physicians and the roles of nutrition support pharmacists in palliative and hospice care cancer patients is limited. The study aimed to analyze the prescribing practices of physicians and the roles of clinical pharmacists at a tertiary cancer center. A retrospective analysis of 12527 electronic records of hospice and palliative care cancer patients. All nutrition support therapy prescriptions by physicians and clinical pharmacists' interventions were recorded. Analysis was conducted utilizing the Jamovi statistical package 2022. The study population comprised inpatients and homecare patients. The most frequently prescribed nutrition support therapy was vitamins and minerals supplements, followed by enteral nutrition and parenteral nutrition. The total number of nutrition support pharmacist interventions was 660 (5.2%). The acceptance rate of interventions by physicians was 90%. Initiating mineral use was the most frequent intervention, followed by discontinuation of mineral use. Vitamins and mineral supplements are the most prescribed type of nutrition support therapy. The interventions of clinical pharmacists were highly accepted by physicians. Initiating mineral use is the most frequent intervention. Further research is needed to explore the impact of nutrition support therapy on patient outcomes and barriers to its implementation.

Background: The burden of hypertension among women of childbearing age in Jordan is increasing, indicating the need to explore its prevalence and associated risk factors. Aim: To assess the prevalence and determinants of hypertension among women aged 18–49 years in Jordan. Methods: This study used secondary cross-sectional data on hypertension, diabetes and hypercholesterolemia from 2675 Jordanian and Syrian women aged 18–49 years from the 2019 WHO STEPS survey in Jordan. Data analysis was performed using SPSS version 28, and univariate analysis was conducted to determine the associations between the variables. Results: Prevalence of hypertension among the study participants was 17% and women who had hypertension were also obese. Having hypertension was significantly associated with being married, having lower educational attainment and consuming high amounts of salt. Those who had hypertension were more likely to have a history of diabetes, hypercholesterolemia and cardiovascular disease (P < 0.05). Conclusions: The 17% prevalence of hypertension among the study participants, alongside obesity, indicates the need for weight management and lifestyle modification interventions to reduce the burden of hypertension among women of childbearing age in Jordan.

M thodes : La pr sente tude a utilis des donn es transversales secondaires sur l'hypertension, le diab te et l'hypercholest rol mie provenant de 2675 femmes jordaniennes et syriennes g es de 18 49 ans dans le cadre de l'enqu te STEPS de l'OMS men e en 2019 en Jordanie. Le traitement des donn es a t r alis l'aide du logiciel SPSS version 28, et une analyse univari e a t effectu e pour d terminer les associations entre les variables. [phrase omitted]

Seasonal influenza significantly impacts global health, especially among high-risk groups such as the elderly. People aged ≥65 years have the highest morbidity and mortality due to influenza infections. Despite international recommendations, influenza vaccine-uptake rates remain low in many regions worldwide. In Jordan, data on influenza vaccine uptake in people aged ≥65 years is lacking. This study aimed to assess vaccination rates, knowledge, attitudes, and barriers among the elderly in Jordan. This national cross-sectional study included 455 adults aged ≥65 years living at representative sites in Jordan in Amman, Irbid, Zarqa, and Karak. The study questionnaire was based on the health belief model and included data on demographics, influenza vaccination history, and knowledge of, attitudes toward, perceptions of, and barriers to influenza vaccine uptake. Only 11.4% of participants received the influenza vaccine in the 2022-2023 season, while 30.1% had ever been vaccinated. Rural residents, higher-income groups, and those insured by private institutions demonstrated higher vaccination rates of 14% and 15.4%, respectively ( <0.05). Barriers to being vaccinated included perceived low susceptibility (43.7%), concerns about adverse effects (52.7%), and lack of social network recommendations (38.9%). Positive predictors included trust in vaccination guidelines, higher perceived risk, and health-care provider advice (P<0.001). Influenza vaccination rates among older adults in Jordan are low compared to regional and international data. Interventions tailored to address barriers are needed to improve awareness, accessibility, and trust to reduce influenza-related morbidity and mortality.

Background Vaccination against influenza is the major primary preventive measure to reduce the major health and economic burden of influenza infections. Children aged 6 months to five years, have been identified as the highest risk group for influenza complications, therefore, it is essential to ensure a high uptake rate of influenza vaccine amongst this age group. Methods A structured questionnaire based on the Health Belief Model was used to collect data from parents through face-to-face interview on influenza vaccine uptake among children from 6 months to 5 years of age in Jordan. It also aimed to assess knowledge, attitudes and barriers towards influenza vaccine for this age group. Results 477 parents completed the study questionnaire. The study revealed a low influenza vaccine uptake rate of 12.0% for the 2022/2023 influenza season. Around one fifth (19.3%) of study participants reported to ever had their child vaccinated against influenza. The study identified several factors motivating parents to get their children vaccinated; such as healthcare professional advice, higher income and history of previous severe influenza infection requiring hospitalization. On the other hand, several barriers related to influenza vaccine were identified; such as cost and concerns about the vaccine safety. Conclusions There is an overall low uptake of influenza vaccine amongst children in Jordan. There is a need for public health programs and more involvement of the healthcare professionals to improve the reported rates of vaccination from Jordan. This is in addition to focusing these programs on reported barriers for the influenza vaccine uptake.

Introduction and Objective: Obesity has increased worldwide, and existing anti-obesity medications have treatment limitations that diminish their overall benefits. This study aimed to investigate the effects of orlistat in combination with Elettaria cardamomum “Cardamom” (CAR) extract on working memory, recognition memory, anxiety, and inflammation within hippocampal tissue. Methods: Mice were categorized into two groups: a control group (CD) and a cafeteria diet (CAF) group induced with obesity (CAF) for 10 weeks. The groups were then subdivided into a CAF group treated with orlistat (CAF-ORL), a CAF group treated with orlistat and Elettaria cardamomum (CAF-ORL-CARD), and a group that continued on the CAF. The CAF-ORL group received orlistat at a dosage of 10 mg/kg/day for four weeks, while the CAF-ORL-CARD group received 10 mg/kg/day of orlistat and 500 mg/kg of CAR extract via oral gavage. In the 14th week, various assessments were conducted, including the novel object recognition (NOR) test, Y maze test, marble-burying test (MBT), open-field test, and TNF-α levels in the hippocampus. Result: TNF-α levels in the hippocampal tissue of the CAF group were elevated compared to the CD group (p < 0.01), whereas the CAF-ORL group exhibited reduced TNF-α levels compared to the CAF group (p < 0.01). Moreover, TNF-α levels in the CAF-ORL-CARD group were significantly lower than in the CAF-ORL group (p < 0.01). The recognition index was notably higher in the CAF-ORL group compared to the CAF group (p < 0.01) and higher in the CAF-ORL-CARD group compared to the CAF-ORL group (p < 0.01). However, there were no changes in the open-field test and Y maze test (p > 0.05). Conclusions: Orlistat combined with CAR has positive effects on neuroinflammation and memory, suggesting that this combination may offer potential therapeutic benefits for cognitive impairments and hippocampal dysfunction associated with obesity.

Chlorpyrifos (CPF) is an organophosphate pesticide widely used in agriculture. It poses significant health risks due to its neurotoxic, hepatotoxic, and reproductive effects. Given that current treatments for the health problems caused by hazardous toxins are inadequate and highlight the need for new treatments, this study investigated the effects of hesperidin, a flavonoid from citrus fruits, in reducing the harmful effects of CPF exposure. Based on the results, hesperidin treatment significantly improved cell viability and reduced oxidative damage markers such as malondialdehyde (MDA) and superoxide dismutase (SOD) levels, along with oxidative stress factors. It can augment the antioxidant cellular defenses via the ERK/Nrf2 signaling pathway, reduce inflammatory targets, and inhibit lipid peroxidation. Histopathological analysis of the organs showed that hesperidin reduced inflammation and collagen accumulation in liver tissue, suggesting its protective role in maintaining liver structure. Furthermore, hesperidin appears to counteract the pro-apoptotic effects of CPF, as evidenced by lower levels of cell death markers. These findings highlight the potential of hesperidin as a therapeutic agent against CPF-induced damage and emphasize its antioxidant and anti-inflammatory properties. This study supports further research into hesperidin and similar plant compounds as potential solutions to pesticide-related health issues. This research advances our understanding of how natural substances can mitigate the harmful effects of environmental pollutants and paves the way for future studies in this area.