Explore the vast range of titles available.

Two novel image denoising algorithms are proposed which employ goodness of fit (GoF) test at multiple image scales. Proposed methods operate by employing the GoF tests locally on the wavelet coefficients of a noisy image obtained via discrete wavelet transform (DWT) and the dual tree complex wavelet transform (DT-CWT) respectively. We next formulate image denoising as a binary hypothesis testing problem with the null hypothesis indicating the presence of noise and the alternate hypothesis representing the presence of desired signal only. The decision that a given wavelet coefficient corresponds to the null hypothesis or the alternate hypothesis involves the GoF testing based on empirical distribution function (EDF), applied locally on the noisy wavelet coefficients. The performance of the proposed methods is validated by comparing them against the state of the art image denoising methods.

Output from imaging sensors based on CMOS and CCD devices is prone to noise due to inherent electronic fluctuations and low photon count. The resulting noise in the acquired image could be effectively modelled as signal-dependent Poisson noise or as a mixture of Poisson and Gaussian noise. To that end, we propose a generalized framework based on detection theory and hypothesis testing coupled with the variance stability transformation (VST) for Poisson or Poisson–Gaussian denoising. VST transforms signal-dependent Poisson noise to a signal independent Gaussian noise with stable variance. Subsequently, multiscale transforms are employed on the noisy image to segregate signal and noise into separate coefficients. That facilitates the application of local binary hypothesis testing on multiple scales using empirical distribution function (EDF) for the purpose of detection and removal of noise. We demonstrate the effectiveness of the proposed framework with different multiscale transforms and on a wide variety of input datasets.

In this era, deep learning-based medical image analysis has become a reliable source in assisting medical practitioners for various retinal disease diagnosis like hypertension, diabetic retinopathy (DR), arteriosclerosis glaucoma, and macular edema etc. Among these retinal diseases, DR can lead to vision detachment in diabetic patients which cause swelling of these retinal blood vessels or even can create new vessels. This creation or the new vessels and swelling can be analyzed as biomarker for screening and analysis of DR. Deep learning-based semantic segmentation of these vessels can be an effective tool to detect changes in retinal vasculature for diagnostic purposes. This segmentation task becomes challenging because of the low-quality retinal images with different image acquisition conditions, and intensity variations. Existing retinal blood vessels segmentation methods require a large number of trainable parameters for training of their networks. This paper introduces a novel Dense Aggregation Vessel Segmentation Network (DAVS-Net), which can achieve high segmentation performance with only a few trainable parameters. For faster convergence, this network uses an encoder-decoder framework in which edge information is transferred from the first layers of the encoder to the last layer of the decoder. Performance of the proposed network is evaluated on publicly available retinal blood vessels datasets of DRIVE, CHASE_DB1, and STARE. Proposed method achieved state-of-the-art segmentation accuracy using a few number of trainable parameters.

In this era, deep learning-based medical image analysis has become a reliable source in assisting medical practitioners for various retinal disease diagnosis like hypertension, diabetic retinopathy (DR), arteriosclerosis glaucoma, and macular edema etc. Among these retinal diseases, DR can lead to vision detachment in diabetic patients which cause swelling of these retinal blood vessels or even can create new vessels. This creation or the new vessels and swelling can be analyzed as biomarker for screening and analysis of DR. Deep learning-based semantic segmentation of these vessels can be an effective tool to detect changes in retinal vasculature for diagnostic purposes. This segmentation task becomes challenging because of the low-quality retinal images with different image acquisition conditions, and intensity variations. Existing retinal blood vessels segmentation methods require a large number of trainable parameters for training of their networks. This paper introduces a novel Dense Aggregation Vessel Segmentation Network (DAVS-Net), which can achieve high segmentation performance with only a few trainable parameters. For faster convergence, this network uses an encoder-decoder framework in which edge information is transferred from the first layers of the encoder to the last layer of the decoder. Performance of the proposed network is evaluated on publicly available retinal blood vessels datasets of DRIVE, CHASE_DB1, and STARE. Proposed method achieved state-of-the-art segmentation accuracy using a few number of trainable parameters.

This paper presents LUVS-Net, which is a lightweight convolutional network for retinal vessel segmentation in fundus images that is designed for resource-constrained devices that are typically unable to meet the computational requirements of large neural networks. The computational challenges arise due to low-quality retinal images, wide variance in image acquisition conditions and disparities in intensity. Consequently, the training of existing segmentation methods requires a multitude of trainable parameters for the training of networks, resulting in computational complexity. The proposed Lightweight U-Net for Vessel Segmentation Network (LUVS-Net) can achieve high segmentation performance with only a few trainable parameters. This network uses an encoder–decoder framework in which edge data are transposed from the first layers of the encoder to the last layer of the decoder, massively improving the convergence latency. Additionally, LUVS-Net’s design allows for a dual-stream information flow both inside as well as outside of the encoder–decoder pair. The network width is enhanced using group convolutions, which allow the network to learn a larger number of low- and intermediate-level features. Spatial information loss is minimized using skip connections, and class imbalances are mitigated using dice loss for pixel-wise classification. The performance of the proposed network is evaluated on the publicly available retinal blood vessel datasets DRIVE, CHASE_DB1 and STARE. LUVS-Net proves to be quite competitive, outperforming alternative state-of-the-art segmentation methods and achieving comparable accuracy using trainable parameters that are reduced by two to three orders of magnitude compared with those of comparative state-of-the-art methods.

Automated detection of vision threatening eye disease based on high resolution retinal fundus images requires accurate segmentation of the blood vessels. In this regard, detection and segmentation of finer vessels, which are obscured by a considerable degree of noise and poor illumination, is particularly challenging. These noises include (systematic) additive noise and multiplicative (speckle) noise, which arise due to various practical limitations of the fundus imaging systems. To address this inherent issue, we present an efficient unsupervised vessel segmentation strategy as a step towards accurate classification of eye diseases from the noisy fundus images. To that end, an ensemble block matching 3D (BM3D) speckle filter is proposed for removal of unwanted noise leading to improved detection. The BM3D-speckle filter, despite its ability to recover finer details (i.e., vessels in fundus images), yields a pattern of checkerboard artifacts in the aftermath of multiplicative (speckle) noise removal. These artifacts are generally ignored in the case of satellite images; however, in the case of fundus images, these artifacts have a degenerating effect on the segmentation or detection of fine vessels. To counter that, an ensemble of BM3D-speckle filter is proposed to suppress these artifacts while further sharpening the recovered vessels. This is subsequently used to devise an improved unsupervised segmentation strategy that can detect fine vessels even in the presence of dominant noise and yields an overall much improved accuracy. Testing was carried out on three publicly available databases namely Structured Analysis of the Retina (STARE), Digital Retinal Images for Vessel Extraction (DRIVE) and CHASE_DB1. We have achieved a sensitivity of 82.88, 81.41 and 82.03 on DRIVE, SATARE, and CHASE_DB1, respectively. The accuracy is also boosted to 95.41, 95.70 and 95.61 on DRIVE, SATARE, and CHASE_DB1, respectively. The performance of the proposed methods on images with pathologies was observed to be more convincing than the performance of similar state-of-the-art methods.

Automated retinal image analysis holds prime significance in the accurate diagnosis of various critical eye diseases that include diabetic retinopathy (DR), age-related macular degeneration (AMD), atherosclerosis, and glaucoma. Manual diagnosis of retinal diseases by ophthalmologists takes time, effort, and financial resources, and is prone to error, in comparison to computer-aided diagnosis systems. In this context, robust classification and segmentation of retinal images are primary operations that aid clinicians in the early screening of patients to ensure the prevention and/or treatment of these diseases. This paper conducts an extensive review of the state-of-the-art methods for the detection and segmentation of retinal image features. Existing notable techniques for the detection of retinal features are categorized into essential groups and compared in depth. Additionally, a summary of quantifiable performance measures for various important stages of retinal image analysis, such as image acquisition and preprocessing, is provided. Finally, the widely used in the literature datasets for analyzing retinal images are described and their significance is emphasized. •An extensive review of the state-of-the-art methods for retinal image analysis.•Existing techniques are categorized into essential groups and compared in depth.•A summary of quantifiable performance measures is presented.•Widely used are described and their significance is emphasized.•A model system for ophthalmic healthcare and monitoring system is proposed.

We propose a novel multivariate signal denoising method that performs long-range correlation analysis of multiple modes in input data by considering inherent inter-channel dependencies of the data. That is achieved through a novel and generic multivariate extension of detrended fluctuation analysis (DFA) method - another contribution of this paper. Specifically, our proposed denoising method first obtains data driven multiscale signal representation using multivariate variational mode decomposition (MVMD) method. Then, the proposed generic multivariate DFA is used to reject the predominantly noisy modes based on their randomness scores. Finally, the denoised signal is reconstructed by summing the remaining modes albeit after the removal of the noise traces using the principal component analysis (PCA).