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Background This study aims at investigating the outcome and electrophysiologic recovery of 150 carpal tunnel syndrome hands after single-portal endoscopic surgery. Methods Patients with the cross-sectional area of the median nerve being 13–15 mm 2 on ultrasound or abnormal sensory nerve conduction velocity on EMG are assigned to endoscopic surgery that cuts the decompressing transverse ligament to avoid the emergence of severe symptoms, such as muscular atrophy and loss of hand function. Results Single-portal endoscopic release is a safe and efficacious option for carpal tunnel release. The findings demonstrate encouraging results. Conclusion The endoscopic carpal tunnel release with the placement of a MicroAire system is a safe and effective method for treating carpal tunnel syndrome.

The aim of the article is to present the first experience of applying a full-endoscopic posterior cervical foraminotomy and discectomy performed at Viet Duc University Hospital in Hanoi and describe the outcomes of such surgical intervention. This surgical series includes 20 patients underwent surgery through full-endoscopic posterior cervical foraminotomy and discectomy. The definitive diagnosis of the patients and the evidence for surgical treatment was radiculopathy due to lateral or intraforaminal disk herniation, foraminal stenosis, and lateral recess stenosis. Patients with discogenic cervical radiculopathy but with a contraindication to endoscopic posterior cervical foraminotomy and discectomy were not subject to surgical intervention. All patients underwent a CT and MRT examination of the cervical spine before and after surgery as complementary diagnostic methods. Besides radiological diagnostic methods, electroneuromyography and spondylography were performed with functional samples, i.e., with head tilts in the front and back, to eliminate segmental instability. The timing and degree of the root pain syndrome regression were assessed using a VAS scale (visual and analog scale) with a subsequent comparison of preoperative and postoperative performance. Immediately after the operation, all patients noted a complete or nearly complete regression of the pain syndrome.

To date, no comprehensive study has evaluated the outcomes of single-level full endoscopic posterior cervical foraminotomy and herniectomy in Vietnam. This prospective, descriptive study was conducted before and after spinal disc herniation surgery at the Department of Spine Surgery, Viet Duc University Hospital, Hanoi, Vietnam, from March 2023 to December 2024. All patients follow-up during the 12 months with clinical, radiological and image outcomes. The study included 47 patients, with 23 males (48.9%) and 24 females (51.1%), with a mean age of 44.46 ± 8.47 years old. The location of the operated disc was predominantly at the C5-C6 level (61.7%) with 10.34 ± 0.7 incision length. The recovery outcomes revealed a strong trend toward excellent and good results, totalling 93.6% of the positive outcomes. A statistically significant reduction in all measured parameters over time (the Numerical Rating Scale (NRS) for pain and the Neck Disability Index (NDI) at multiple time points: pre-operation, post-operative day 1, and 1, 6, and 12 months post-operation) compared to pre-operative baseline values (p < 0.0001 for all comparisons). Radiological outcomes showed significantly improved cervical neural curvature from to C2-C7 at all the postoperative time points. Foraminal dimensions (height, diameter, and area) showed significant immediate postoperative increases. Disc height decreased significantly, while cervical range of motion showed variable changes. C2-C7 SVA and T1 slope remained stable, indicating no significant changes in the global alignment. Complications were generally low; two patients had intraoperative nerve root injury, and one patient had transient root palsy. This study demonstrated that single-level full endoscopic posterior cervical foraminotomy and herniectomy are safe in the short-term with 12 months of follow-up and effective in the treatment of cervical disc herniation. Further study is needed with a larger sample size, with control group and long-term follow-up.

The purpose of this research is to evaluate the results of arthroscopic suture fixation with fiber wires used as treatment for ACL avulsion fracture, and to determine how effective such a technique is when it comes to restoring of knee function. This prospective study involves 28 patients, who underwent arthroscopic fixation of displaced ACL avulsion fractures at Saint Paul Hospital (Hanoi) from January 2014 to March 2018. The first 3 weeks were not marked with any abnormalities associated with postoperative sutures and hematomas; infectious complications were not detected either. Postoperative displacement of fracture fragments did not take place among the patients involved in the study. At the 3-month follow-up, the average IKDC score was 90.7 (range 76–100), and the average Lysholm score was 93.6 (range 82–100). The percentage of excellent scores was 42.9% (12 patients), good scores accounted for 50% (14 patients), while fair/poor scores accounted for 3.6% each (one patient on each score). The percentage of excellent/good scores was 92.9% in total. This study shows that ACL avulsion fracture can be treated effectively by arthroscopic suture fixation with fiber wires. In fact, this technique may restore knee function and stability.

Modern real-time applications are becoming more demanding computationally while their temporal requirements, dictated by the physical world, often remain unchanged. This coupled with the increasing prevalence of multiprocessors in real-time systems necessitates that highly computation-demanding real-time tasks need to be parallelized to exploit the parallelism offered by the underlying hardware, in order to satisfy their temporal constraints. Scheduling parallel real-time tasks, however, introduces a new layer of complexity due to the allowance for intra-task parallelism. This dissertation addresses the problem of scheduling parallel real-time tasks in which tasks may (or may not) access shared non-processor resources, such as in-memory buffers or data structures. Specifically, for independent tasks, we propose new scheduling algorithms and schedulability analyses for parallel tasks with these characteristics, under federated and global scheduling. Experimental results show that the proposed algorithms and analyses improve the previously introduced methods. For parallel tasks that may access shared non-processor resources, we present a blocking analysis for two different types of spinlocks; through evaluations, we make a recommendation for a preferable ordering of locks. We also study practical runtime parallel scheduler designs for soft real-time applications and present a design that is more suitable for soft real-time systems.

The original version of this article unfortunately contained a mistake. One affiliation was incorrect.

The median duration of hospital stays due to COVID-19 has been reported in several studies on China as 10-13 days. Global studies have indicated that the length of hospitalisation depends on different factors, such as the time elapsed from exposure to symptom onset, and from symptom onset to hospital admission, as well as specificities of the country under study. The goal of this paper is to identify factors associated with the median duration of hospital stays of COVID-19 patients during the second COVID-19 wave that hit Vietnam from 5 March to 8 April 2020. We used retrospective data on 133 hospitalised patients with COVID-19 recorded over at least two weeks during the study period. The Cox proportional-hazards regression model was applied to determine the potential risk factors associated with length of hospital stay. There were 65 (48.9%) females, 98 (73.7%) patients 48 years old or younger, 15 (11.3%) persons with comorbidities, 21 (16.0%) severely ill patients and 5 (3.8%) individuals with life-threatening conditions. Eighty-two (61.7%) patients were discharged after testing negative for the SARS-CoV-2 virus, 51 were still in the hospital at the end of the study period and none died. The median duration of stay in a hospital was 21 (IQR: 16-34) days. The multivariable Cox regression model showed that age, residence and sources of contamination were significantly associated with longer duration of hospitalisation. A close look at how long COVID-19 patients stayed in the hospital could provide an overview of their treatment process in Vietnam, and support the country's National Steering Committee on COVID-19 Prevention and Control in the efficient allocation of resources over the next stages of the COVID-19 prevention period.

The identification and quantification of actionable mutations are of critical importance for effective genotype-directed therapies, prognosis and drug response monitoring in patients with non-small-cell lung cancer (NSCLC). Although tumor tissue biopsy remains the gold standard for diagnosis of NSCLC, the analysis of circulating tumor DNA (ctDNA) in plasma, known as liquid biopsy, has recently emerged as an alternative and noninvasive approach for exploring tumor genetic constitution. In this study, we developed a protocol for liquid biopsy using ultra-deep massively parallel sequencing (MPS) with unique molecular identifier tagging and evaluated its performance for the identification and quantification of tumor-derived mutations from plasma of patients with advanced NSCLC. Paired plasma and tumor tissue samples were used to evaluate mutation profiles detected by ultra-deep MPS, which showed 87.5% concordance. Cross-platform comparison with droplet digital PCR demonstrated comparable detection performance (91.4% concordance, Cohen's kappa coefficient of 0.85 with 95% CI = 0.72-0.97) and great reliability in quantification of mutation allele frequency (Intraclass correlation coefficient of 0.96 with 95% CI = 0.90-0.98). Our results highlight the potential application of liquid biopsy using ultra-deep MPS as a routine assay in clinical practice for both detection and quantification of actionable mutation landscape in NSCLC patients.

A simple approach was developed to synthesize cobalt ferrite nanoparticles/graphene quantum dots (CF/GQDs). The material was prepared from a homogeneous mixture of iron nitrate, cobalt nitrate, and starch at 140, 180 and 200 °C in a 24 h thermal hydrolysis process. The obtained materials were characterised by using X-ray diffraction, scanning electron microscopy, transmission electron microscopy, ultraviolet–visible diffuse reflectance spectroscopy, Fourier-transform infrared spectroscopy, photoluminescence spectroscopy, vibrating-sample magnetometry, and nitrogen adsorption/desorption isotherms. Cobalt ferrite crystals of around 8–10 nm and graphene quantum dots formed directly at 200 °C. Stacking GQDs sheets onto the CF nanoparticles resulted in CF/GQDs nanoparticles. The nanocomposite exhibits satisfactory fluorescent and superparamagnetic properties, which are vital for catalytic applications. The CF/GQDs catalyse significantly the degradation of methylene blue (MB) under visible light. The catalyst can be recycled with an external magnetic field and displays suitable stability. Also, it was reused in three successive experiments with a loss of efficiency of about 5%. The CF/GQDs are considered as an efficient photocatalyst for MB degradation and other dyes.