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Strategies Using Gelatin Microparticles for Regenerative Therapy and Drug Screening Applications
Gelatin, a denatured form of collagen, is an attractive biomaterial for biotechnology. In particular, gelatin particles have been noted due to their attractive properties as drug carriers. The drug release from gelatin particles can be easily controlled by the crosslinking degree of gelatin molecule, responding to the purpose of the research. The gelatin particles capable of drug release are effective in wound healing, drug screening models. For example, a sustained release of growth factors for tissue regeneration at the injured sites can heal a wound. In the case of the drug screening model, a tissue-like model composed of cells with high activity by the sustained release of drug or growth factor provides reliable results of drug effects. Gelatin particles are effective in drug delivery and the culture of spheroids or cell sheets because the particles prevent hypoxia-derived cell death. This review introduces recent research on gelatin microparticles-based strategies for regenerative therapy and drug screening models.
Journal Article
Kimono refashioned : Japan's impact on international fashion
\"Kimono Refashioned explores the impact of kimono on the world of fashion from the 1870s to now. Featuring works from the renowned Kyoto Costume Institute, it includes Japanese and Western designs, men's and women's apparel, and both exacting and impressionistic references to kimono. Kimono has influenced global fashion since Japan opened to the world in the late nineteenth century. Motifs used to decorate kimono, its form and silhouette, and its two-dimensional structure and linear cut have all been refashioned into a wide array of garments. Kimono revealed new possibilities in clothing design and helped to lay the foundations of contemporary clothing. Six essays from experts in the field discuss Japan's impact on international fashion. Four catalogue sections explore early examples of the influence of kimono; Japonism in fashion from the late nineteenth century to the 1920s; contemporary fashion and its use of kimono's flatness, silhouette, weave, dyeing, and decoration; and how Japan continues to inspire the world of fashion through its incorporation of popular design, including manga and anime\"-- Provided by publisher.
Book
Classical equation of motion and anomalous dimensions at leading order
A
bstract
Motivated by a recent paper by Rychkov-Tan [1], we calculate the anomalous dimensions of the composite operators at the leading order in various models including a
ϕ
3
-theory in (6 −
ϵ
) dimensions. The method presented here relies only on the classical equation of motion and the conformal symmetry. In case that only the leading expressions of the critical exponents are of interest, it is sufficient to reduce the multiplet recombination discussed in [1] to the classical equation of motion. We claim that in many cases the use of the classical equations of motion and the CFT constraint on two- and three-point functions completely determine the leading behavior of the anomalous dimensions at the Wilson-Fisher fixed point without any input of the Feynman diagrammatic calculation. The method developed here is closely related to the one presented in [1] but based on a more perturbative point of view.
Journal Article
Generalized Giveon-Kutasov duality
A
bstract
We generalize the Giveon-Kutasov duality by adding possible Chern-Simons interactions for the U(
N
) gauge group. Some of the generalized dualities are known in the literature and many others are new to the best of our knowledge. The dualities are connected to the non-supersymmetric bosonization duality via mass deformations. For
N
= 1, there are an infinite number of magnetic-dual theories.
Journal Article
Electric current control of spin helicity in an itinerant helimagnet
A helimagnet is a chiral magnet in which the direction of the magnetic moment spatially rotates in a plane perpendicular to the propagation vector. The sense of the rotation known as spin helicity is a robust degree of freedom of matter and may provide a new concept of magnetic memory if it can be electrically controlled and detected. Here we show that the helicity can be controlled by magnetic fields and electric currents in an itinerant helimagnet MnP. Second-harmonic resistivity measurements allow us to read out the controlled helicity. In contract to an insulating multiferroic magnet, in which spin rotation was shown to be controllable by an electric field, we achieve helicity manipulation by using an electric current in the conducting helimagnet. The controllability of the spin helicity may pave the way to new method of realizing magnetic memories based on the spin internal degrees of freedom.
The spin helicity in helimagnets may be exploited in magnetic memory applications if electrically controllable and detectable. Here, helicity manipulation driven by an electric current and detection by second harmonic resistivity measurements in an itinerant helimagnet MnP is demonstrated.
Journal Article
Magnetization control by angular momentum transfer from surface acoustic wave to ferromagnetic spin moments
Interconversion between electron spin and other forms of angular momentum is useful for spin-based information processing. Well-studied examples of this are the conversion of photon angular momentum and rotation into ferromagnetic moment. Recently, several theoretical studies have suggested that the circular vibration of atoms work as phonon angular momentum; however, conversion between phonon angular momentum and spin-moment has yet to be demonstrated. Here, we demonstrate that the phonon angular momentum of surface acoustic wave can control the magnetization of a ferromagnetic Ni film by means of the phononic-to-electronic conversion of angular momentum in a Ni/LiNbO
3
hybrid device. The result clearly shows that the phonon angular momentum is useful for increasing the functionality of spintronic devices.
Conversion of an external angular momentum, for example, from mechanical rotation or light into ferromagnetic moment has a long history. Here, Sasaki et al. demonstrate the conversion of phonon angular momentum, in ferromagnetic moment, potentially allowing for new types of control for spintronics.
Journal Article
“Chiral” and “non-chiral” 3d Seiberg duality
A
bstract
We propose a Seiberg duality for a 3d
N
= 2 Spin (7) gauge theory with
F
spinor matters. For
F ≥
6, the theory allows a magnetic dual description with an SU(
F −
4) gauge group. The matter content on the magnetic side is “chiral” and the duality connects “chiral” and “non-chiral” 3d gauge theories. As a corollary, we can construct a Seiberg duality for a 3d
N
= 2
G
2
gauge theory with fundamental matters.
Journal Article
Emerging and Neglected Infectious Diseases: Insights, Advances, and Challenges
Infectious diseases are a significant burden on public health and economic stability of societies all over the world. They have for centuries been among the leading causes of death and disability and presented growing challenges to health security and human progress. The threat posed by infectious diseases is further deepened by the continued emergence of new, unrecognized, and old infectious disease epidemics of global impact. Over the past three and half decades at least 30 new infectious agents affecting humans have emerged, most of which are zoonotic and their origins have been shown to correlate significantly with socioeconomic, environmental, and ecological factors. As these factors continue to increase, putting people in increased contact with the disease causing pathogens, there is concern that infectious diseases may continue to present a formidable challenge. Constant awareness and pursuance of effective strategies for controlling infectious diseases and disease emergence thus remain crucial. This review presents current updates on emerging and neglected infectious diseases and highlights the scope, dynamics, and advances in infectious disease management with particular focus on WHO top priority emerging infectious diseases (EIDs) and neglected tropical infectious diseases.
Journal Article
Biomaterial-Assisted Regenerative Medicine
This review aims to show case recent regenerative medicine based on biomaterial technologies. Regenerative medicine has arousing substantial interest throughout the world, with “The enhancement of cell activity” one of the essential concepts for the development of regenerative medicine. For example, drug research on drug screening is an important field of regenerative medicine, with the purpose of efficient evaluation of drug effects. It is crucial to enhance cell activity in the body for drug research because the difference in cell condition between in vitro and in vivo leads to a gap in drug evaluation. Biomaterial technology is essential for the further development of regenerative medicine because biomaterials effectively support cell culture or cell transplantation with high cell viability or activity. For example, biomaterial-based cell culture and drug screening could obtain information similar to preclinical or clinical studies. In the case of in vivo studies, biomaterials can assist cell activity, such as natural healing potential, leading to efficient tissue repair of damaged tissue. Therefore, regenerative medicine combined with biomaterials has been noted. For the research of biomaterial-based regenerative medicine, the research objective of regenerative medicine should link to the properties of the biomaterial used in the study. This review introduces regenerative medicine with biomaterial.
Journal Article