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This article considers the model of recognition in the Gender Recognition Act 2004 (GRA) and, through a critique of the value of stability pursued through this legislation, argues that recognition as a model is incompatible with the variety of experiences of non-binary trans-identified individuals. The article then moves on to analyse self-declaration, part of the proposed reform recently dismissed by the Government. While self-declaration contains provisions that would minimise the length of the process of recognition as well as the level of intrusiveness and stigma associated with it, this analysis highlights some fundamental theoretical concerns with its over-reliance on the strict dialectical logics on recognition and its structural inability to account for and respond to the challenges posed by non-binary trans individuals.

“There's no need to fear or hope, but only to look for new weapons” (Deleuze 1992, 4) José Esteban Muñoz opens his book Cruising Utopia: The Then and There of Queer Futurity by stating that “queerness is not here yet. Queerness is an ideality … an ideality that can be distilled from the past and used to imagine a future.” Queerness, continues Muñoz, “is a longing that propels us onward … Queerness is essentially about the rejection of the here and now” (2009, 1). He identifies queer utopias with an idea of futurity as an attempt to think of something else that goes beyond the “here and now,” an act of resistance: “the present is not enough. It is impoverished and toxic for queers and other people who do not feel the privilege of majoritarian belonging, normative tastes and ‘rational’ expectations … The present must be known in relation to the alternative temporal and spatial maps provided by a perception of past and future affective worlds” (27). In this article, I aim to show just the opposite. The argument I make here is that queer utopia—transgender—is a futurity of the here and of the now, a virtuality that does not belong to the past nor does it lend itself to projections of the future, but it is totally immersed in the very now of the present.

The built environment and the organisation of public spaces reflect the normative notions of male and female. Public toilets, amongst other widely common public spaces, underline these two opposing concepts and challenge the presence of transgender. Within the boundaries of public toilets, transgender and gender non-conforming individuals become a crucial point of debate, scrutiny and controversy. Analysing the politics of such gender-segregated space, this article explores the notion of uniformity and challenges the idea of single-ness as the absolute expression of the self.

This PhD focuses on transgender subjectivity and explores the ways in which trans is negotiated and compromised by and within social space, with particular attention to the dynamics and socio-cultural norms through which the transgendered body that identifies beyond the gender binary is mediated. The existence of trans subjectivity develops in opposition to institutionalised heteronormativity; its problematic social location and identification make it a phenomenon which strongly relies on movement and spatiality. Part of what makes trans so compelling is not so much its breach of the ‘natural body’, but it is the unique form of self-description it carries within itself which retains the potential of opening up a new narrative and alternative possibility for the very notion of gender and for all LGBT advocacy and its relations to space. My theoretical framework is influenced by the work of Gilles Deleuze. I look at trans as a mode of unified affirmation and not as a product of negotiation (medical and/or legal). Difference for Deleuze is not an empirical condition but an ontological constitutional principle. Through this, I elaborate a conceptual framework of understanding wherein transgender subjectivity is articulated in terms of utopianism. The utopianism I refer to is not wishful hope, rather, it is the material embodiment here and now of that mode of futurity transgender subjectivity evokes. Futurity contains within itself the seed for producing the re-energisation of thought and ‘ethical space’ does not only entail the inclusion of what is real and tangible but must also account for what is possible, because what is possible is real.

Background/Objectives: Surgical site infections are a serious public health concern, representing a significant burden on healthcare systems and society. Their occurrence is influenced by several factors, including patient demographics, healthcare facilities and the specific circumstances surrounding surgery. The use of prophylactic antibiotics in this context carries both potential benefits and risks. The aim of this study is to investigate potential risk factors that may adversely affect the development of SSIs, as well as to assess the appropriateness and adherence to perioperative antibiotic prophylaxis. Methods: This observational study was conducted from October 2023 to October 2024 at the University Hospital of Messina, Italy, a hospital performing both thoracic and vascular surgery. Data were collected using a questionnaire regarding socio-demographic data, risk factors, clinical and surgical data and details regarding the administration of antibiotics. Results: This study included 117 patients with an average age of 63 ± 12.36 SD years, 70.9% from the Thoracic Surgery Unit and 29.1% from the Vascular Surgery Unit. The most administered antibiotic was cefazolin, and antibiotic administration time was in compliance with the guidelines. Conclusions: Our data show that the implementation of evidence-based guidelines, healthcare professionals’ education and correct antibiotic use can reduce the burden of SSIs by improving patient care.

Background: Vaccination constitutes a low-cost, safe, and efficient public health measure that can help prevent the spread of infectious diseases and benefit the community. The fact that vaccination effectiveness varies among populations, and that the causes of this are still unclear, indicates that several factors are involved and should be thoroughly examined. The “intestinal microbiota” is the most crucial of these elements. Numerous clinical studies demonstrate the intestinal microbiota’s significance in determining the alleged “immunogenicity” and efficacy of vaccines. This systematic review aimed to review all relevant scientific literature and highlight the role of intestinal microbiota in COVID-19, Salmonella typhi, Vibrio cholerae, and rotavirus vaccinations. Materials and Methods: The MESH terms “vaccines” and “microbiota” were used to search the major scientific databases PubMed, SciVerse Scopus, Web of Knowledge, and the Cochrane Central Register of Controlled Clinical Trials. Results: Between February 2024 and October 2024, the analysis was conducted using electronic databases, yielding a total of 235 references. Finally, 24 RCTs were chosen after meeting all inclusion criteria: eight studies of COVID-19, two studies of Salmonella typhi, three studies of Vibrio cholerae, and eleven studies of rotavirus. Only six of these demonstrated good study quality with a Jadad score of three or four. Conclusions: According to the review’s results, the intestinal microbiota surely plays a role in vaccinations’ enhanced immunogenicity, especially in younger people. As it is still unclear what mechanisms underlie this effect, more research is needed to better understand the role of the intestinal microbiota.

Background and Aim: In 2021, healthcare expenditure in Italy represented 7.3% of the national gross domestic product, with approximately 80% attributed to the management of chronic diseases—an increasing burden associated with population aging. Population stratification tools have emerged as critical instruments for the efficient allocation of healthcare resources, particularly for high-need, high-cost individuals. This systematic review aimed to identify, classify, and evaluate existing population stratification tools based on their characteristics, validation status, and practical applications. Methods: A systematic literature review was conducted in accordance with the PRISMA 2020 guidelines to examine adult population stratification models grounded in healthcare needs. The review encompassed studies retrieved from major scientific databases and included both national and international implementations. Results: The initial search yielded 140,111 records, from which 17 distinct stratification tools were identified. Of these, nine had undergone validation through peer-reviewed studies. Within the Italian context, only six tools were in active use—three of which were developed as region-specific algorithms, while the remaining three employed internationally established software platforms. Conclusions: Population stratification tools provide a robust framework for assessing both clinical complexity and resource utilization, thereby facilitating the design of integrated care pathways and evidence-based policy decisions. In the context of proactive and personalized healthcare delivery, such tools play a pivotal role in enhancing system efficiency, informing strategic planning, and promoting equitable access to care.