Catalogue Search | MBRL
Are you sure you want to remove the book from the shelf?
{{itemTitle}}
382
result(s) for
"O'Doherty, Brian"
Sort by:
Improvement in health status with once-daily indacaterol/glycopyrronium 110/50 μg in COPD patients: real-world evidence from an observational study in Ireland
AimsIndacaterol/glycopyrronium (IND/GLY) 110/50 μg is a once-daily (o.d.) fixed-dose combination of long-acting β2-agonist/long-acting muscarinic antagonist approved in over 90 countries, including Ireland, for the management of COPD. The present study was conducted to evaluate health status of COPD patients, initiated on IND/GLY 110/50 μg o.d., using the Clinical COPD Questionnaire (CCQ) tool in a real-world primary care setting in Ireland.MethodsThis was a real-world, prospective, open-label study. COPD patients aged > 40 years and with a smoking history of > 10 pack-years were included and switched to once-daily IND/GLY 110/50 μg. Enrolment of patients into the study occurred only after the decision had been made by the physician to prescribe IND/GLY 110/50 μg. Data were collected at baseline and Week 26. Health status was assessed using the validated CCQ.ResultsA total of 200 patients were included in study. The mean CCQ total score decreased from 2.36 at baseline to 1.44 at Week 26 (Δ, 0.92; P < 0.0005). Of the 156 patients who completed study, 113 (72.4%) achieved minimum clinically important difference in CCQ total score with IND/GLY 110/50 μg. CCQ domain scores also decreased during the study. Improvement in health status was observed across all GOLD groups and irrespective of prior COPD treatment. Adverse events were reported by 20% of patients with COPD exacerbation/infected COPD being the most common AE, reported by 11 patients.ConclusionsIn real-life clinical practice in Ireland, IND/GLY 110/50 μg o.d. demonstrated statistically significant and clinically important improvement in health status in patients with COPD.
Journal Article
Azithromycin in primary care
These conditions respond very well to Zithromax. There is also excellent coverage of the normal bacteria that cause infection in the respiratory tract, i.e. Streptococcus pneumoniae, Moraxella catarrhalisor Haemophilus infìuenzae. In the guidelines for the treatment of community-acquired pneumonia, Zithromax is one of the drugs of choice, as it gives very good coverage for these particular pathogens.
Trade Publication Article
THE DEVELOPMENT OF AGENCY THOUGHT: A CITATION ANALYSIS OF THE LITERATURE
With the advent of new bibliographic data sources and new analytical techniques, accounting historians may now trace the development of accounting thought with the aid of bibliometric analysis. The objective of this paper is to discuss a social science view of history, discuss essential bibliometric concepts, and provide an example of citation analysis applied to the literature of agency theory — to demonstrate its use in historical research.
Journal Article
Why young Scandinavian women keep having hits
[...]from Sweden, the dark indie artist began her career a decade ago, and since then has dropped a string of critically-acclaimed albums - though she is perhaps most known in pop charts for her single I Follow Rivers, which went to number two in Ireland. At the last moment, two oiled-up, muscle-bound, blonde men appear instead, to sweat their way through the background of the track while the singing duo remain at their decks, smiling to themselves. Norway is becoming a new hub, as Oslo's fashion world, Bergen's rap scene, globalisation, feminism and countless other influences are reshaping the sound and soul of Scandipop.
Newspaper Article