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PurposeDCIS has been shown to have a higher rate of positive margins following breast-conserving surgery (BCS) than invasive breast cancer. We aim to analyze certain factors of DCIS, specifically histologic grade and estrogen receptor (ER) status, in patients with positive surgical margins following BCS to determine if there is an association.MethodsA retrospective review of our institutional patient registry was performed to identify women with DCIS and microinvasive DCIS who underwent BCS by a single surgeon from 1999 to 2021. Demographics and clinicopathologic characteristics between patients with and without positive surgical margins were compared using chi-square or Student’s t-test. We assessed factors associated with positive margins using univariate and multivariable logistic regression.ResultsOf the 615 patients evaluated, there was no significant difference in demographics between the patients with and without positive surgical margins. Increasing tumor size was an independent risk factor for margin positivity (P =  < 0.001). On univariate analysis both high histologic grade (P = 0.009) and negative ER status (P =  < 0.001) were significantly associated with positive surgical margins. However, when adjusted in multivariable analysis, only negative ER status remained significantly associated with margin positivity (OR = 0.39 [95% CI 0.20–0.77]; P = 0.006).ConclusionThe study confirms increased tumor size as a risk factor for positive surgical margins. We also demonstrated that ER negative DCIS was independently associated with a higher rate of positive margins after BCS. Given this information, we can modify our surgical approach to reduce rate of positive margins in patients with large-sized ER negative DCIS.

The objective of this study is to evaluate food wastage attitudes and the impact of social media among the United Arab Emirates (UAE) population. A questionnaire was distributed via social network applications (n = 525). The majority of the respondents were females (84%) and social media users (99%). Most of the respondents were well aware of the problem of food wastage (96%). Half of the respondents (53.7 and 48.8%) reported taking some form of action on an ‘often’ basis to reduce food wastage, and buying food as per their needs, respectively. Two-thirds (66.7%) of the respondents stated that their family did not throw away anything from their last meal. A majority (82.3%) felt uncomfortable upon discarding food. A mixed response was observed in terms of food wastage and social media usage. On one hand, using social media was significantly (p < 0.05) associated with measuring the exact quantity of ingredients prior to preparation, lower overall family wastage, eating leftovers, and composting. On the other hand, less-frequent social media users significantly (p < 0.05) had fewer leftovers, checked expiry dates, were more serious about food wastage, and planned to minimize it. Social media should be used with prudence as it may not have a very significant impact on food wastage reduction.

The band structures of Zn-based hydroxyapatites co-doped with Mg at varying amounts from 0 to 2.0 at. % have been investigated theoretically in more detail. The calculations were done to obtain the band structure, density of states, and band gap for all the modeled structures to study their electronic properties. It was seen that the co-doping has an effect on the structural and electronic properties of all the as-investigated structures. The bandgap energy for all samples in each group was found to be reduced gradually with varying doping rates of Mg into Zn-doped HAp. The band gap decreased from 4.54 to 3.84 eV for samples of 0.4Zn–0.4 Mg-HAp and 2.0Zn–0.4 Mg-HAp with the same amount of Mg, respectively, as a result of increasing the doping levels of Zn from 0.4 to 2.0 at.%. The lattice parameters, unit cell volume, and density decrease with increase in doping of Zn-containing HAp and in addition of second dopant Mg at varying amounts 0.4 , 0 . 8 , 1.2 , 1.6, and 2.0 at . % in all of the modeled sample group. Furthermore, it is observed that the declining values of the aforementioned parameters are significantly impacted by the increasing Zn doping rates.