Explore the vast range of titles available.

Emotions play a crucial role in shaping consumer experiences and decisions. Neurophysiological tools offer objective markers of emotional reactions in multisensory environments, where positive valence promotes approach behavior and negative valence fosters avoidance. We applied the Osgood semantic differential (SD) to establish correspondences between visual, auditory, and olfactory stimuli and target emotions relevant to retail zoning. Based on SD results, we selected stimuli to create multisensory environments. These were presented in immersive virtual reality (VR) to 27 participants. Emotional responses were assessed via heart rate (HR), heart rate variability (HRV), and electrodermal activity (EDA). SD analysis identified cross-modal associations between sensory stimuli and retail zones, allowing refinement of semantic positioning. VR experiments revealed that HRV significantly increased in pleasant environments, indicating enhanced parasympathetic activation. HR and EDA showed no significant correlation with emotional valence, though both displayed trends toward reduction in pleasant conditions. Our findings suggest that HRV is a reliable physiological marker of consumers' approach behavior in multisensory retail environments, whereas HR and EDA are less sensitive. Combining SD with VR-based neurophysiological assessment enables objective evaluation of emotional zoning strategies, offering a scientifically grounded alternative to intuitive design practices for optimizing consumer experience.

The purpose of this work was to realize the reproductive qualities of sows and the productivity of young pigs with immunotropic preparations PigStim-C and PigStim-M. To set up the experiment, 30 heads of nursing sows were selected on the 15th day after the first farrowing. The selected sows were divided into 3 groups according to the breed, reproductive qualities and reproductive health according to the principle of pairs of analogues. It was found that intramuscular injection of the immunotropic drug PigStim-C to animals of the 1st experimental group (and PigStim-M to animals of the 2nd experimental group) at a dose of 5 ml per head on the 15th, 20th, and 25th day after farrowing contributes to: reducing the period from weaning to coming into heat and the onset of the optimal period for insemination by 4.5-9.1%; an increase in the success of insemination from 90% in the control group to 100%; an improvement in sows’ prolificacy by 8.1-8.6% and a decrease in the number of stillborn piglets by 16.7-33.3%; a decrease in the number of sows with prolonged farrowing by 2-3 times resulting in a decrease in the occurrence of postpartum pathologies of reproductive organs, such as metritis-mastitis-agalactia syndrome, as well as an increase in the therapeutic measures' efficiency in case of their occurence; a decrease in the disease incidence of young pigs obtained from these sows during the next farrowing by 36.8-41.5%, an increase in their viability by 1.45-2.97% and an increase in live weight at the end of the growing period by 0.16-0.18 kg, rearing – by 1.1-1.22 kg, and when removed from fattening – by 3.6-4.0 kg.

The dynamics of the activity and selectivity of bifunctional platinum tungstated zirconia PtWZ catalyst in the hydroisomerization of n-heptane and heptane–benzene mixture is discussed in the paper. The change in the properties of the catalyst before and after reaction were characterized using different techniques. The catalyst showed high efficiency for the hydroisomerization of heptane and heptane–benzene mixture, however, deactivation occurred with time on stream, more significantly when benzene was present in the reaction mixture. The carbonaceous matter was deposited on the catalyst (up to 0.8%) during the hydroisomerization reaction. Predominantly aliphatic carbonaceous «poly-CxHy» species, much less oxidized and little aromatic «graphite-like» species were identified by XPS spectra on the catalyst after the heptane isomerization. In the presence of benzene, the formation of «graphite-like» matter increased progressively as temperature increased. However, no appreciable changes in the bulk properties of the t-ZrO2 matrix (phase composition, specific surface area, pore volume, pore size distribution) and in the state of platinum component were revealed, though an increased extent of W6+ to W5+ reduction was detected by XPS spectra irrespectively of the reaction conditions. The deactivation of the PtWZ catalyst was suggested to result from the blocking the active centers by carbonaceous deposits, the deactivation of the acidic centers being more pronounced as compared to metallic ones. All the carbonaceous deposits were burned-off completely below 450–500 °C.Graphical Abstract

Functional movement disorder (FMD) is a common manifestation of functional neurological disorder presenting with diverse phenotypes such as tremor, weakness and gait disorder. Our current understanding of the basic epidemiological features of this condition is unclear. We aimed to describe and examine the relationship between age at onset, phenotype and gender in FMD in a large meta-analysis of published and unpublished individual patient cases. An electronic search of PubMed was conducted for studies from 1968 to 2019 according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Individual patient data were collected through a research network. We described the distribution of age of onset and how this varied by gender and motor phenotype. A one-stage meta-analysis was performed using multilevel mixed-effects linear regression, including random intercepts for country and data source. A total of 4905 individual cases were analysed (72.6% woman). The mean age at onset was 39.6 years (SD 16.1). Women had a significantly earlier age of onset than men (39.1 years vs 41.0 years). Mixed FMD (23.1%), tremor (21.6%) and weakness (18.1%) were the most common phenotypes. Compared with tremor (40.7 years), the mean ages at onset of dystonia (34.5 years) and weakness (36.4 years) were significantly younger, while gait disorders (43.2 years) had a significantly later age at onset. The interaction between gender and phenotype was not significant. FMD peaks in midlife with varying effects of gender on age at onset and phenotype. The data gives some support to ‘lumping’ FMD as a unitary disorder but also highlights the value in ‘splitting’ into individual phenotypes where relevant.

The effect of the addition of La3+ cations on the structural properties of Pt/WOх/ZrO₂ catalysts and the characteristics of catalytic activity in the process of hydroisomerization of n-heptane and benzene mixture was studied. The phase composition of the catalysts is represented by a solid solution of lanthanum cations in nanocrystalline zirconia of tetragonal modification with localization of lanthanum in the surface layers predominantly. The positive effect of La3+ additives on the selectivity and yield of isomerized products was shown

The dynamics of the activity and selectivity of bifunctional platinum tungstated zirconia PtWZ catalyst in the hydroisomerization of n-heptane and heptane–benzene mixture is discussed in the paper. The change in the properties of the catalyst before and after reaction were characterized using different techniques. The catalyst showed high efficiency for the hydroisomerization of heptane and heptane–benzene mixture, however, deactivation occurred with time on stream, more significantly when benzene was present in the reaction mixture. The carbonaceous matter was deposited on the catalyst (up to 0.8%) during the hydroisomerization reaction. Predominantly aliphatic carbonaceous «poly-C x H y » species, much less oxidized and little aromatic «graphite-like» species were identified by XPS spectra on the catalyst after the heptane isomerization. In the presence of benzene, the formation of «graphite-like» matter increased progressively as temperature increased. However, no appreciable changes in the bulk properties of the t -ZrO 2 matrix (phase composition, specific surface area, pore volume, pore size distribution) and in the state of platinum component were revealed, though an increased extent of W 6+ to W 5+ reduction was detected by XPS spectra irrespectively of the reaction conditions. The deactivation of the PtWZ catalyst was suggested to result from the blocking the active centers by carbonaceous deposits, the deactivation of the acidic centers being more pronounced as compared to metallic ones. All the carbonaceous deposits were burned-off completely below 450–500 °C. Graphical Abstract

The dynamics of the activity and selectivity of bifunctional platinum tungstated zirconia PtWZ catalyst in the hydroisomerization of n-heptane and heptane-benzene mixture is discussed in the paper. The change in the properties of the catalyst before and after reaction were characterized using different techniques. The catalyst showed high efficiency for the hydroisomerization of heptane and heptane-benzene mixture, however, deactivation occurred with time on stream, more significantly when benzene was present in the reaction mixture. The carbonaceous matter was deposited on the catalyst (up to 0.8%) during the hydroisomerization reaction. Predominantly aliphatic carbonaceous \"poly-C.sub.xH.sub.y\" species, much less oxidized and little aromatic \"graphite-like\" species were identified by XPS spectra on the catalyst after the heptane isomerization. In the presence of benzene, the formation of \"graphite-like\" matter increased progressively as temperature increased. However, no appreciable changes in the bulk properties of the t-ZrO.sub.2 matrix (phase composition, specific surface area, pore volume, pore size distribution) and in the state of platinum component were revealed, though an increased extent of W.sup.6+ to W.sup.5+ reduction was detected by XPS spectra irrespectively of the reaction conditions. The deactivation of the PtWZ catalyst was suggested to result from the blocking the active centers by carbonaceous deposits, the deactivation of the acidic centers being more pronounced as compared to metallic ones. All the carbonaceous deposits were burned-off completely below 450-500 °C.

The effect of the addition of La3+ cations on the structural properties of Pt/WOx/ZrO2 catalysts and the characteristics of catalytic activity in the process of hydroisomerization of n-heptane and benzene mixture was studied. The phase composition of the catalysts is represented by a solid solution of lanthanum cations in nanocrystalline zirconia of tetragonal modification with localization of lanthanum in the surface layers predominantly. The positive effect of La3+ additives on the selectivity and yield of isomerized products was shown.

Spatial suppression (SS) is a visual perceptual phenomenon that is manifest in a reduction of directional sensitivity for drifting high-contrast gratings whose size exceeds the center of the visual field. Gratings moving at faster velocities induce stronger SS. The neural processes that give rise to such size- and velocity-dependent reductions in directional sensitivity are currently unknown, and the role of surround inhibition is unclear. In magnetoencephalogram (MEG), large high-contrast drifting gratings induce a strong gamma response (GR), which also attenuates with an increase in the gratings’ velocity. It has been suggested that the slope of this GR attenuation is mediated by inhibitory interactions in the primary visual cortex. Herein, we investigate whether SS is related to this inhibitory-based MEG measure. We evaluated SS and GR in two independent samples of participants: school-age boys and adult women. The slope of GR attenuation predicted inter-individual differences in SS in both samples. Test-retest reliability of the neuro-behavioral correlation was assessed in the adults, and was high between two sessions separated by several days or weeks. Neither frequencies nor absolute amplitudes of the GRs correlated with SS, which highlights the functional relevance of velocity-related changes in GR magnitude caused by augmentation of incoming input. Our findings provide evidence that links the psychophysical phenomenon of SS to inhibitory-based neural responses in the human primary visual cortex. This supports the role of inhibitory interactions as an important underlying mechanism for spatial suppression. •The role of surround inhibition in perceptual spatial suppression (SS) is debated.•Gamma response (GR) to large moving gratings reflects surround inhibition.•Stronger GR attenuation with increasing velocity is associated with stronger SS.•The neuro-behavioral correlation is replicated in school-age boys and adult women.•The surround inhibition in the V1 is an important mechanism underlying SS.

Tumor cells of acute lymphoblastic leukemia (ALL) may have various genetic abnormalities. Some of them lead to a complete loss of certain genes. Our aim was to reveal biallelic deletions of genes in Ph–negative T-ALL. Chromosomal microarray analysis (CMA) was performed for 47 patients with de novo Ph–negative T-ALL, who received treatment according to RALL-2016m clinical protocol at the National Medical Research Center for Hematology (Moscow, Russia) from 2017 to 2023. Out of forty-seven patients, only three had normal molecular karyotype. The other 44 patients had multiple gains, losses, and copy neutral losses of heterozygosity. Biallelic losses were found in 14 patients (30%). In ten patients (21%), a biallelic deletion of 9p21.3 involved a different number of genes, however CDKN2A gene loss was noted in all ten cases. For seven patients (15%), a biallelic deletion of 7q34 was found, including two genes—PRSS1, PRSS2 located within the T-cell receptor beta (TRB) locus. A clonal rearrangement of the TRB gene was revealed in 6 out of 7 cases with 7q34 biallelic loss. Both biallelic deletions can be considered favorable prognostic factors, with an association with 9p21 being statistically significant (p = 0.01) and a trend for 7q34 (p = 0.12) being observed.