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Fused filament fabrication is among the most widely used 3D printing techniques, that allows to create complex devices from a continuous filament of a polymeric material. This adaptable technique has garnered considerable interest for the development of components functioning under severe radiation environments, including particle accelerators and nuclear reactors. In this work, we evaluated the radiation effects on several categories of commercial printing materials, namely the poly(lactic acid) (PLA), the acrylonitrile butadiene styrene (ABS), and a thermoplastic elastomer (TPE). Printing filaments have been exposed to x-rays (up to 160 keV) at 0.60 Gy s −1 , from 45 kGy to 2 MGy. The results from tensile tests, thermal analyses (differential scanning calorimetry, thermogravimetric analysis, dynamic mechanical thermal analysis), and spectroscopy tests (Fourier transform infrared spectroscopy and Raman analysis) reveal a dose-dependent degradation of material properties, predominantly affecting mechanical properties rather than chemical and thermal ones. The PLA shows the lowest radiation tolerance among the three, dramatically decreasing the tensile strength above 100 kGy, while TPE and ABS reach a comparable mechanical degradation after 1 MGy and 2 MGy, respectively. Radiation-induced effects are investigated, and the degradation is primarily attributed to chain scission as the principal damage mechanism.

[...]clinical registries may suffer imperfect case ascertainment (especially treatment-based registries because they do not record the rates of the underlying disease) and missing and invalid data-some of which is missing by design and some through failure to accurately record data at source. 13 14 In addition, clinical registries do not usually have information about healthcare episodes other than the specific one for which they were designed or longer-term major adverse cerebrovascular and cardiovascular events. [...]the authors did not report data missingness which is a known to be associated with mortality-though in a study using Myocardial Ischaemia National Audit Project data this didn't affect the distribution of hospitals showing special cause variation. 13 What Siregar et al do is emphasise the critical role national electronic healthcare records play in comparative effectiveness research.

The AEgIS experiment located at the Antiproton Decelerator at CERN aims to measure the gravitational fall of a cold antihydrogen pulsed beam. The precise observation of the antiatoms in the Earth gravitational field requires a controlled production and manipulation of antihydrogen. The neutral antimatter is obtained via a charge exchange reaction between a cold plasma of antiprotons from ELENA decelerator and a pulse of Rydberg positronium atoms. The current custom electronics designed to operate the 5 and 1 T Penning traps are going to be replaced by a control system based on the ARTIQ & Sinara open hardware and software ecosystem. This solution is present in many atomic, molecular and optical physics experiments and devices such as quantum computers. We report the status of the implementation as well as the main features of the new control system.

Low-temperature antihydrogen atoms are an effective tool to probe the validity of the fundamental laws of Physics, for example the Weak Equivalence Principle (WEP) for antimatter, and -generally speaking- it is obvious that colder atoms will increase the level of precision. After the first production of cold antihydrogen in 2002 [1], experimental efforts have substantially progressed, with really competitive results already reached by adapting to cold antiatoms some well-known techniques pre- viously developed for ordinary atoms. Unfortunately, the number of antihydrogen atoms that can be produced in dedicated experiments is many orders of magnitude smaller than of hydrogen atoms, so the development of novel techniques to enhance the production of antihydrogen with well defined (and possibly controlled) conditions is essential to improve the sensitivity. We present here some experimental results achieved by the AEgIS Collaboration, based at the CERN AD (Antiproton Decelerator) on the production of antihydrogen in a pulsed mode where the production time of 90% of atoms is known with an uncertainty of ~ 250 ns [2]. The pulsed antihydrogen source is generated by the charge-exchange reaction between Rydberg positronium ( Ps* ) and an antiproton ( p¯ ): p¯ + P s * → H¯ * + e − , where Ps* is produced via the implantation of a pulsed positron beam into a mesoporous silica target, and excited by two consecutive laser pulses, and antiprotons are trapped, cooled and manipulated in Penning-Malmberg traps. The pulsed production (which is a major milestone for AEgIS) makes it possible to select the antihydrogen axial temperature and opens the door for the tuning of the antihydrogen Rydberg states, their de-excitation by pulsed lasers and the manipulation through electric field gradients. In this paper, we present the results achieved by AEgIS in 2018, just before the Long Shutdown 2 (LS2), as well as some of the ongoing improvements to the system, aimed at exploiting the lower energy antiproton beam from ELENA [3].

The efficient production of cold antihydrogen atoms in particle traps at CERN's Antiproton Decelerator has opened up the possibility of performing direct measurements of the Earth's gravitational acceleration on purely antimatter bodies. The goal of the AEgIS collaboration is to measure the value of g for antimatter using a pulsed source of cold antihydrogen and a Moiré deflectometer/Talbot-Lau interferometer. The same antihydrogen beam is also very well suited to measuring precisely the ground-state hyperfine splitting of the anti-atom. The antihydrogen formation mechanism chosen by AEgIS is resonant charge exchange between cold antiprotons and Rydberg positronium. A series of technical developments regarding positrons and positronium (Ps formation in a dedicated room-temperature target, spectroscopy of the n=1-3 and n=3-15 transitions in Ps, Ps formation in a target at 10 K inside the 1 T magnetic field of the experiment) as well as antiprotons (high-efficiency trapping of , radial compression to sub-millimetre radii of mixed plasmas in 1 T field, high-efficiency transfer of to the antihydrogen production trap using an in-flight launch and recapture procedure) were successfully implemented. Two further critical steps that are germane mainly to charge exchange formation of antihydrogen-cooling of antiprotons and formation of a beam of antihydrogen-are being addressed in parallel. The coming of ELENA will allow, in the very near future, the number of trappable antiprotons to be increased by more than a factor of 50. For the antihydrogen production scheme chosen by AEgIS, this will be reflected in a corresponding increase of produced antihydrogen atoms, leading to a significant reduction of measurement times and providing a path towards high-precision measurements. This article is part of the Theo Murphy meeting issue 'Antiproton physics in the ELENA era'.

The primary goal of the AEgIS collaboration at CERN is to measure the gravitational acceleration on neutral antimatter. Positronium (Ps), the bound state of an electron and a positron, is a suitable candidate for a force-sensitive inertial measurement by means of deflectometry/interferometry. In order to conduct such an experiment, the impact position and time of arrival of Ps atoms at the detector must be detected simultaneously. The detection of a low-velocity Ps beam with a spatial resolution of (88 ± 5) μm was previously demonstrated [1]. Based on the methodology employed in [1] and [2], a hybrid imaging/timing detector with increased spatial resolution of about 10 μm was developed. The performance of a prototype was tested with a positron beam. The concept of the detector and first results are presented.

From the experimental point of view, very little is known about the gravitational interaction between matter and antimatter. In particular, the Weak Equivalence Principle, which is of paramount importance for the General Relativity, has not yet been directly probed with antimatter. The main goal of the AEgIS experiment at CERN is to perform a direct measurement of the gravitational force on antimatter. The idea is to measure the vertical displacement of a beam of cold antihydrogen atoms, traveling in the gravitational field of the Earth, by the means of a moiré deflectometer. An overview of the physics goals of the experiment, of its apparatus and of the first results is presented.

Bariatric surgery is an accepted treatment option for severe obesity. Previous analysis of the independently collected Hospital Episode Statistics (HES) data for outcomes after bariatric surgery demonstrated a 30-day postoperative mortality rate of 0·3 per cent in the English National Health Service (NHS). However, there have been no published mortality data for bariatric procedures performed since 2008. This study aimed to assess mortality related to bariatric surgery in England from 2009. HES data were used to identify all patients who had primary bariatric surgery from 2009 to 2016. Clinical codes were used selectively to identify all primary bariatric procedures but exclude revision or conversion procedures and operations for malignant or other benign disease. The primary outcome measures were HES in-hospital and Office for National Statistics (ONS) 30-day mortality after discharge. A total of 41 241 primary bariatric procedures were carried out in the NHS between 2009 and 2016, with 29 in-hospital deaths (0·07 per cent). The 30-day mortality rate after discharge was 0·08 per cent (32 of 41 241). Both the in-hospital and 30-day mortality rates after discharge demonstrated a downward trend over the study period. Overall in-hospital and 30-day mortality rates remain very low after primary bariatric surgery. An increased uptake of bariatric surgery within the English NHS has been safe.

AEg¯IS (Antimatter Experiment: Gravity, Interferometry, Spectroscopy) is a CERN based experiment aiming to probe the Weak Equivalence Principle of General Relativity with antimatter by studying free fall of antihydrogen in the Earth's gravitational field. A pulsed cold beam of antihydrogen produced by charge exchange between Rydberg positronium and cold antiprotons will be horizontally accelerated by an electric field gradient. The free fall of antihydrogen will then be measured by a classical moire deflectometer. An overview of the experimental setup, present status of the experiment along with current achievements and results is presented.

The AEgIS (Antimatter Experiment: Gravity, Interferometry, Spectroscopy) experiment is designed with the objective to test the weak equivalence principle with antimatter by studying the free fall of antihydrogen in the Earth's gravitational field. A pulsed cold beam of antihydrogen will be produced by charge exchange between cold Ps excited in Rydberg state and cold antiprotons. Finally the free fall will be measured by a classical moiré deflectometer. The apparatus being assembled at the Antiproton Decelerator at CERN will be described, then the advancements of the experiment will be reported: positrons and antiprotons trapping measurements, Ps two-step excitation and a test-measurement of antiprotons deflection with a small scale moiré deflectometer.