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310 result(s) for "Patrick Heinrich"
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Ryukyuan Perspectives for Language Reclamation
Reclamation is focused on the effects of learning one’s heritage language. (2015, p. 1) define new speakers as “individuals with little or no home or community exposure to a minority language but who instead acquire it through immersion or bilingual educational programs, revitalization projects or as adult language learners.” In the absence of bilingual education programs, new speakers in the Ryukyus reclaim their heritage languages in informal contexts (Hammine 2019, 2020; Zlazli 2021). Propelled outside the old trajectory of language shift and loss, and in view of the linguistic, social, and emotional difficulties that language reclamation brings about, learning and speaking a Ryukyuan language needs to make sense.
The tox is in the detail: technical fundamentals for designing, performing, and interpreting experiments on toxicity of microplastics and associated substances
Over the last 10 years, there has been a plethora of experimental studies estimating the potential of microplastic particles (MPs) to exert toxic effects in the environment, many specifically focusing on their postulated capacity to enhance the transfer of environmental pollutants into organisms after ingestion. Obviously, there is little to no consensus on appropriate experimental design, which is mainly owing to the novelty, the interdisciplinarity of the subject, and the complexity of parameters involved. This results in fundamental discrepancies regarding the materials applied, the approach for spiking MPs with pollutants, and the exact exposure scenario. Aiming for a non-chemist audience and providing illustrative, representative, and comparative examples, this review first outlines the theoretical essentials of processes involved in sorption. Also, it discusses the implications for designing experimental approaches using MPs and interpreting the results obtained under consideration of their relevance for environmental conditions. It may help to improve the interpretation of studies on MP toxicity already published, while also calling experimenters’ attention to various aspects important to consider when designing and performing environmentally relevant experiments with MPs.
The Making of Monolingual Japan
Japan is widely regarded as a model case of successful language modernization, and it is often erroneously believed to be linguistically homogenous. There is a connection between these two views. As the first ever non-Western language to be modernized, Japanese language modernizers needed to convince the West that Japanese was just as good a language as the national languages of the West. The result was a fervent desire for linguistic uniformity. Today the legacy of modernist language ideology poses many problems to an internationalizing Japan. All indigenous minority languages are heading towards extinction, and this purposefully created homogeneity also affects the integration of immigrants and their languages. This book examines these issues from the perspective of language ideology, and in doing so the mechanisms by which language ideology undermines linguistic diversity are revealed.
Impact of blood meals taken on ivermectin-treated livestock on survival and egg production of the malaria vector Anopheles coluzzii under laboratory conditions
Treatment of livestock with endectocides such as ivermectin is viewed as a complementary vector control approach to address residual transmission of malaria. However, efficacy of this treatment may vary between animal species. Hence, our purpose was to investigate the effects of ivermectin treatments of common livestock species on life history traits of the opportunistic malaria vector Anopheles coluzzii . Sheep, goats and pigs were treated using injectable veterinary ivermectin formulation at the species-specific doses (recommended dose for all species and high dose in pig). Mosquito batches were exposed to treated and control (not injected) animals at different days after treatment. Daily mosquito mortality was recorded and fecundity assessed through the count of gravid females and the number of eggs they developed. The recommended dose of ivermectin induced a significant decrease in mosquito survival for up to 7 days after injection (DAI), with a decrease of 89.7%, 66.7%, and 48.4% in treated pigs, goats and sheep, respectively, compared to control animals. In treated pigs, the triple therapeutic dose decreased mosquito survival of 68.97% relatively to controls up to 14 DAI. The average number in gravid females Anopheles that survived after feeding on treated animals were reduced when blood-meals were taken on sheep (2.57% and 42.03% at 2 and 7 DAI), or on goats (decrease of the 28.28% and 73.64% respectively at 2 and 7 DAI). This study shows that ivermectin treatments to animals negatively impacts An . coluzzii life history traits and could reduce vector densities in areas where livestock live near humans. However, due to short-term efficacy of single dose treatments, repeated treatments and potentially increased dosages would be required to span the transmission season. The use of long-acting ivermectin formulations is discussed as a mean for extending efficacy while remaining cost effective.
Development and Implementation of an e-Trigger Tool for Adverse Drug Events in a Swiss University Hospital
The purpose of the study was to develop and implement an institution-specific trigger tool based on the Institute for Healthcare Improvement medication module trigger tool (IHI MMTT) in order to detect and monitor ADEs. We performed an investigator-driven, single-center study using retrospective and prospective patient data to develop (\"development phase\") and implement (\"implementation phase\") an efficient, institution-specific trigger tool based on the IHI MMTT. Complete medical data from 1008 patients hospitalized in 2018 were used in the development phase. ADEs were identified by chart review. The performance of two versions of the tool was assessed by comparing their sensitivities and specificities. Tool A employed only digitally extracted triggers (\"e-trigger-tool\") while Tool B employed an additional manually extracted trigger. The superior tool - taking efficiency into account - was applied prospectively to 19-22 randomly chosen charts per month for 26 months during the implementation phase. In the development phase, 189 (19%) patients had ≥1 ADE (total 277 ADEs). The time needed to identify these ADEs was 15 minutes/chart. A total of 203 patients had ≥1 trigger (total 273 triggers - Tool B). The sensitivities and specificities of Tools A and B were 0.41 and 0.86, and 0.43 and 0.86, respectively. Tool A was more time-efficient than Tool B (4 vs 9 minutes/chart) and was therefore used in the implementation phase. During the 26-month implementation phase, 22 patients experienced trigger-identified ADEs and 529 did not. The median number of ADEs per 1000 patient days was 6 (range 0-13). Patients with at least one ADE had a mean hospital stay of 22.3 ± 19.7 days, compared to 8.0 ± 7.6 days for those without an ADE (p = 2.7×10 ). We developed and implemented an e-trigger tool that was specific and moderately sensitive, gave consistent results and required minimal resources.
Routledge Handbook of Japanese Sociolinguistics
Presenting new approaches and results previously inaccessible in English, the Routledge Handbook of Japanese Sociolinguistics provides an insight into the languages and society of contemporary Japan from a fresh perspective. While it was once believed that Japan was a linguistically homogenous country, research over the past two decades has shown Japan to be a multilingual and sociolinguistically diversifying country. Building on this approach, the contributors to this handbook take this further, combining Japanese and western approaches alike and producing research which is relevant to twenty-first century societies. Organised into five parts, the sections covered include: The languages and language varieties of Japan. The multilingual ecology. Variation, style and interaction. Language problems and language planning. Research overviews. With contributions from across the field of Japanese sociolinguistics, this handbook will prove very useful for students and scholars of Japanese studies, as well as sociolinguists more generally.