Explore the vast range of titles available.

Genetic population assignment used to inform wildlife management and conservation efforts requires panels of highly informative genetic markers and sensitive assignment tests. We explored the utility of machine‐learning algorithms (random forest, regularized random forest and guided regularized random forest) compared with FST ranking for selection of single nucleotide polymorphisms (SNP) for fine‐scale population assignment. We applied these methods to an unpublished SNP data set for Atlantic salmon (Salmo salar) and a published SNP data set for Alaskan Chinook salmon (Oncorhynchus tshawytscha). In each species, we identified the minimum panel size required to obtain a self‐assignment accuracy of at least 90% using each method to create panels of 50–700 markers Panels of SNPs identified using random forest‐based methods performed up to 7.8 and 11.2 percentage points better than FST‐selected panels of similar size for the Atlantic salmon and Chinook salmon data, respectively. Self‐assignment accuracy ≥90% was obtained with panels of 670 and 384 SNPs for each data set, respectively, a level of accuracy never reached for these species using FST‐selected panels. Our results demonstrate a role for machine‐learning approaches in marker selection across large genomic data sets to improve assignment for management and conservation of exploited populations.

Despite considerable effort, most smokers relapse within a few months after quitting due to cigarette craving. The widespread adoption of mobile phones presents new opportunities to provide support during attempts to quit. To design and pilot a mobile app \"DistractMe\" to enable quitters to access and share distractions and tips to cope with cigarette cravings. A qualitative study with 14 smokers who used DistractMe on their mobiles during the first weeks of their quit attempt. Based on interviews, diaries, and log data, we examined how the app supported quitting strategies. Three distinct techniques of coping when using DistractMe were identified: diversion, avoidance, and displacement. We further identified three forms of engagement with tips for coping: preparation, fortification, and confrontation. Overall, strategies to prevent cravings and their effects (avoidance, displacement, preparation, and fortification) were more common than immediate coping strategies (diversion and confrontation). Tips for coping were more commonly used than distractions to cope with cravings, because they helped to fortify the quit attempt and provided opportunities to connect with other users of the application. However, distractions were important to attract new users and to facilitate content sharing. Based on the qualitative results, we recommend that mobile phone-based interventions focus on tips shared by peers and frequent content updates. Apps also require testing with larger groups of users to assess whether they can be self-sustaining.

Laypeople increasingly use the Internet as a source of health information, but finding and discovering the right information remains problematic. These issues are partially due to the mismatch between the design of consumer health websites and the needs of health information seekers, particularly the lack of support for \"exploring\" health information. The aim of this research was to create a design for consumer health websites by supporting different health information-seeking behaviors. We created a website called Better Health Explorer with the new design. Through the evaluation of this new design, we derive design implications for future implementations. Better Health Explorer was designed using a user-centered approach. The design was implemented and assessed through a laboratory-based observational study. Participants tried to use Better Health Explorer and another live health website. Both websites contained the same content. A mixed-method approach was adopted to analyze multiple types of data collected in the experiment, including screen recordings, activity logs, Web browsing histories, and audiotaped interviews. Overall, 31 participants took part in the observational study. Our new design showed a positive result for improving the experience of health information seeking, by providing a wide range of information and an engaging environment. The results showed better knowledge acquisition, a higher number of page reads, and more query reformulations in both focused and exploratory search tasks. In addition, participants spent more time to discover health information with our design in exploratory search tasks, indicating higher engagement with the website. Finally, we identify 4 design considerations for designing consumer health websites and health information-seeking apps: (1) providing a dynamic information scope; (2) supporting serendipity; (3) considering trust implications; and (4) enhancing interactivity. Better Health Explorer provides strong support for the heterogeneous and shifting behaviors of health information seekers and eases the health information-seeking process. Our findings show the importance of understanding different health information-seeking behaviors and highlight the implications for designers of consumer health websites and health information-seeking apps.

Online groups rely on contributions from their members to flourish, but in the context of behaviour change individuals are typically reluctant to participate actively before they have changed successfully. We took inspiration from CSCW research on objects to address this problem by shifting the focus of online participation from the exchange of personal experiences to more incidental interactions mediated by objects that offer support for change. In this article we describe how we designed, deployed and studied a smartphone application that uses different objects, called distractions and tips, to facilitate social interaction amongst people trying to quit smoking. A field study with 18 smokers revealed different forms of interaction: purely instrumental interactions with the objects, subtle engagement with other users through receptive and covert interactions, as well as explicit interaction with other users through disclosure and mutual support. The distraction objects offered a stepping-stone into interaction, whereas the tips encouraged interaction with the people behind the objects. This understanding of interaction through objects complements existing frameworks of online participation and adds to the current discourse on object-centred sociality. Furthermore, it provides an alternative approach to the design of online support groups, which offers the users enhanced control about the information they share with other users. We conclude by discussing how researchers and practitioners can apply the ideas of interaction around objects to other domains where individuals may have a simultaneous desire and reluctance to interact.

IntroductionThis study aims primarily to characterize the sequelae and morbidity associated with tibial pilon injuries from the patients’ perspectives in terms of multiple surgical interventions, duration of hospital stay, downtime from work, loss of productivity and impact on patients’ lives. The secondary aim is to review the associated risk factors for these morbidities.Materials and methodsAll patients with surgically treated tibial pilon fractures from 1st July 2007 to 30th June 2017 were included. The morbidities reviewed focused on delay to surgery, numbers of surgeries, limb amputation, length of stay (LOS), readmissions, duration of medical leave (ML), follow-up and number of outpatient visits.ResultsThere were 102 patients included in the review and up to 70% of them had an average 7 days delay to definitive surgery. They also required an average hospital LOS of at least 2 weeks extending up to 3 more weeks if soft tissue reconstruction was necessitated. Up to a third of patients were readmitted with 15% of them needing further treatment. These patients required a notable period of downtime from work as shown in the long ML (mean 152.6 days [S.D. = 110.7]). Multiple conditional regression models showed AO/OTA classification (B and C) and open fracture as independent predictors of delay to surgery. Predictors for increased LOS were high velocity mechanism of injury at 4 days longer and patients who needed soft tissue reconstruction at 21 days longer. In terms of downtime from work, only work injury has been identified as an independent predictor of ML at 88.5 days longer.ConclusionTibial pilon fractures leads to significant morbidities with profound negative impact on patients’ lives in terms of multiple surgical interventions required, prolonged hospital stay, need for readmissions and prolonged downtime from work. These morbidities from patients’ perspective should be emphasized to patients and employers to manage their expectations and potential limitations.

The Internet has become an important source of health information for many people, including non-medical experts. While much health information is provided through the Internet, such information is often spread across multiple websites and providers. With the decentralised nature of the Internet, people are often unable to access health information at a single point, and thus extra efforts are needed for seeking information with search engines. The information seeking process is a crucial step for obtaining the needed health information. According to prior research, seekers apply an exploratory approach in the information seeking process of health-related topics. Although information seeking behaviours have been studied extensively in past research, few details specifically about information seeking in the health context can be found. This paper reports on a qualitative study that investigates the information needs and behaviours of health information seekers. Based on the results of the study, we present a model conceptualising health information seeking behaviours as well as the characteristics of the exploratory search approach observed in the health information seeking process.

IntroductionOperative treatment of tibial pilon fracture is challenging. There is a lack of consensus and only one clinical study on the optimal location of distal tibial plating for fixation of pilon fractures based on varus or valgus fracture patterns. We hypothesize that complications rates, specifically mechanical complications, are not influenced by the location of the tibial plating in the fixation of pilon fractures with respect to varus or valgus fracture patterns.Materials and methodsSixty-nine patients who had single plating for tibial pilon from 2007 to 2017 were recruited. They were divided into two groups, transverse fibular fracture (varus fracture pattern) and comminuted fibular fracture (valgus fracture pattern). Our primary outcome measure was any mechanical complications as a result of the location of plating (medial vs lateral) on varus or valgus fracture patterns.ResultsThere were 38 (55.1%) patients with varus fracture pattern and 31 (44.9%) patients with valgus fracture pattern tibial pilon fractures. In the varus fracture pattern group, mechanical complications were not significantly different between the two plating locations (27.3 vs 33.3%, p > 0.05). Notably, there were more fibula fixations performed in patients with medial plating (74.1 vs 45.5%, p = 0.092) when compared those with lateral plating in the varus fracture pattern group. There were also no statistically significant differences found although 10 (40%) out of 25 patients had mechanical complications in the medial plating group compared to 1 (16.7%) out of 6 patients with lateral plating (p = 0.383) in the valgus fracture pattern group.ConclusionThere were no differences in mechanical complications for medial vs lateral plating in tibial pilon fracture based on varus or valgus deforming forces. As much as we should consider the fracture patterns and deforming forces when deciding on plating location, other factors such as careful soft tissue management and fragment-specific fixation should be prioritized.

In this article we focus on the widely researched motivational construct, interest, with the aim of identifying the character of positive affect associated with students' interests. There is a well-documented association between interest and students' engagement with classroom activities. It is also widely accepted that enjoyment plays a role in the dynamic processes operating when students engage with interesting learning activities. We used an innovative measure (MINE) that invites participants to explore and nominate their interests from a relatively large pool of interests. Young adolescent students (N = 213, mean age 13 years 6 months) explored this interactive space to select interests and then had the opportunity to expand on the selected interests through text comments as well as ratings on affective and experiential scales. On average students chose approximately 5 interests and we describe the distribution of interest content for these choices. As expected there were differences between boys and girls in their patterns of interests. Using the students' ratings of their interests on 7 affect terms we found that across all of the nominated interests there was a consistent pattern; high ratings of \"happy,\" \"excited,\" and \"proud,\" moderate to high ratings for \"hopeful,\" and very low ratings for the negative affect terms, \"frustrated,\" \"anxious,\" and \"sad.\" This pattern was consistent across interest content and gender groups. Individual profiles of the affective responses associated with 2 students' chosen interests are described and some of the insights these profiles offer to teachers are explored. Knowledge of how specific positive feelings are active when students engage with the content of their interests will assist practitioners to understand how interests might be used to personalize learning activities and curriculum choices in the service of greater student engagement with learning.

In this article we focus on the widely researched motivational construct, interest, with the aim of identifying the character of positive affect associated with students’ interests. There is a well-documented association between interest and students’ engagement with classroom activities. It is also widely accepted that enjoyment plays a role in the dynamic processes operating when students engage with interesting learning activities. We used an innovative measure (MINE) that invites participants to explore and nominate their interests from a relatively large pool of interests. Young adolescent students (N = 213, mean age 13 years 6 months) explored this interactive space to select interests and then had the opportunity to expand on the selected interests through text comments as well as ratings on affective and experiential scales. On average students chose approximately 5 interests and we describe the distribution of interest content for these choices. As expected there were differences between boys and girls in their patterns of interests. Using the students’ ratings of their interests on 7 affect terms we found that across all of the nominated interests there was a consistent pattern; high ratings of happy, excited, and proud, moderate to high ratings for hopeful, and very low ratings for the negative affect terms, frustrated, anxious, and sad. This pattern was consistent across interest content and gender groups. Individual profiles of the affective responses associated with 2 students’ chosen interests are described and some of the insights these profiles offer to teachers are explored. Knowledge of how specific positive feelings are active when students engage with the content of their interests will assist practitioners to understand how interests might be used to personalize learning activities and curriculum choices in the service of greater student engagement with learning.