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"Pel, Martin"
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Gluck : art and identity
\"Hannah Gluckstein (who called herself Gluck; 1895-1976) was a distinctive, original voice in the early evolution of modern art in Britain. This handsome book presents a major reassessment of Gluck'slife and work, examining, among other things, the artist'snumerous personal relationships and contemporary notions of gender and social history. Gluck'spaintings comprise a full range of artistic genres--still life, landscape, portraiture--as well as images of popular entertainers. Financially independent and somewhat freed from social convention, Gluck highlighted her sexual identity, cutting her hair short and dressing as a man, and the artistis known for a powerful series of self-portraits that played with conventions of masculinity and femininity. Richly illustrated, this volume is a timely and significant contribution to gender studies and to the understanding of a complex and important modern painter.
\"-- Provided by publisher.
\"-- Provided by publisher.
Book
Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88
The filamentous fungus
Aspergillus niger
is widely exploited by the fermentation industry for the production of enzymes and organic acids, particularly citric acid. We sequenced the 33.9-megabase genome of
A. niger
CBS 513.88, the ancestor of currently used enzyme production strains. A high level of synteny was observed with other aspergilli sequenced. Strong function predictions were made for 6,506 of the 14,165 open reading frames identified. A detailed description of the components of the protein secretion pathway was made and striking differences in the hydrolytic enzyme spectra of aspergilli were observed. A reconstructed metabolic network comprising 1,069 unique reactions illustrates the versatile metabolism of
A. niger
. Noteworthy is the large number of major facilitator superfamily transporters and fungal zinc binuclear cluster transcription factors, and the presence of putative gene clusters for fumonisin and ochratoxin A synthesis.
Journal Article
What are the functional and clinical characteristics shared by fibromyalgia and low back pain? A scoping review
Background
Fibromyalgia and chronic primary low back pain are two chronic pain conditions with a significant biopsychosocial burden. Recently, the International Association for the Study of Pain has grouped them under the term chronic primary pain. To further explore similarities and differences between these two conditions, the objective of this scoping review is to explore the pain-related, physiological and psychological outcomes in individuals with fibromyalgia and low back pain.
Methods
The following databases were used to find relevant studies, using the PRISMA guidelines: Medline, Psycinfo, and CINAHL. Studies were included if they encompassed both participants with fibromyalgia or low back pain, with the objective to compare pain-related, physiological and/or psychological outcomes.
Results
Nineteen studies were selected for extraction. Among the 2801 participants, 968 had fibromyalgia (mean age 48.56 ± 7.97 years, with 94% being female) and 896 had low back pain (mean age 47.48 ± 8.15 years, with 80% being female). Pain sensitivity, physical dysfunction, illness perception, psychological distress, alexithymia, depression, and anxiety were generally more severe in participants with fibromyalgia. Most studies found similar levels of pain intensity, kinesiophobia, quality of pain, quality of life, impact of pain, suicidal risk, anger, and social support comparing individuals with fibromyalgia and individuals with low back pain.
Discussion
This scoping review highlights that although both conditions show similar pain intensity and impact on quality of life, fibromyalgia is associated with greater overall severity than low back pain, especially in sensitivity to pain and depression/anxiety.
Journal Article
Evolving Trends in the Management of Acute Appendicitis During COVID-19 Waves: The ACIE Appy II Study
Background
In 2020, ACIE Appy study showed that COVID-19 pandemic heavily affected the management of patients with acute appendicitis (AA) worldwide, with an increased rate of non-operative management (NOM) strategies and a trend toward open surgery due to concern of virus transmission by laparoscopy and controversial recommendations on this issue. The aim of this study was to survey again the same group of surgeons to assess if any difference in management attitudes of AA had occurred in the later stages of the outbreak.
Methods
From August 15 to September 30, 2021, an online questionnaire was sent to all 709 participants of the ACIE Appy study. The questionnaire included questions on personal protective equipment (PPE), local policies and screening for SARS-CoV-2 infection, NOM, surgical approach and disease presentations in 2021. The results were compared with the results from the previous study.
Results
A total of 476 answers were collected (response rate 67.1%). Screening policies were significatively improved with most patients screened regardless of symptoms (89.5% vs. 37.4%) with PCR and antigenic test as the preferred test (74.1% vs. 26.3%). More patients tested positive before surgery and commercial systems were the preferred ones to filter smoke plumes during laparoscopy. Laparoscopic appendicectomy was the first option in the treatment of AA, with a declined use of NOM.
Conclusion
Management of AA has improved in the last waves of pandemic. Increased evidence regarding SARS-COV-2 infection along with a timely healthcare systems response has been translated into tailored attitudes and a better care for patients with AA worldwide.
Journal Article
Modeling and Simulation of Device Performance in Organic Photovoltaics
We present a pipeline to study the device performance of organic solar cells in silico. We introduce a mathematical model that includes the dynamics of excitons as well as their dissociation at bulk heterojunctions within the nanomorphology of the active layer. This is combined with realistic morphologies that we obtain from a detailed phase field model. To solve the coupled nonlinear system, we use a finite element discretization, robust linear solvers, and three numerical schemes, Newton, Gummel, and Semi--Newton--Gummel. This allows for an efficient simulation of the complete OPV device and results in current-voltage curves that can readily be compared to measured data.
Paper