Explore the vast range of titles available.

Angelica sinensis, a highly valued Chinese herb renowned for its medicinal and nutritional properties, occupies a distinctive position in montane agriculture. The remote sensing monitoring of grain crops and their driving factors has been extensively studied, yet research on medicinal cash crops, particularly Angelica sinensis, remains limited. This study employed Landsat imagery and a two-step supervised classification method to map Angelica sinensis cultivation areas in southern Gansu Province while also assessing and projecting climate change impacts on its spatial distribution and yield based on the MaxEnt model and CMIP6 models. The results revealed a pronounced upward altitudinal shift in Angelica sinensis cultivation between 1990 and 2020, with the proportion of cultivation areas above 2400 m increasing from 28.75% to 67.80%. Climate factors explained 59.07% of the spatial distribution of Angelica sinensis, with precipitation, temperature, and altitude identified as the key environmental factors influencing its spatial distribution, yield, and growth. Projections for 2020 to 2060 indicate that Angelica sinensis cultivation areas will continue to shift to higher altitudes, accompanied by overall declines in both suitable area and yield. Under the SSP5-8.5 scenario, nearly all suitable areas are expected to be confined to altitudes above 2400 m by 2060, with 41.46% occurring above 2800 m. By 2060, the yield is expected to decrease to 361–421 kg/mu (down 20–31% from 2020) while the suitable area is projected to shrink to 0.98–1.80 million mu (40–60% smaller than 2040) under different scenarios. This study provides new insights into the protection and sustainable management of Angelica sinensis under changing climatic conditions, offering a scientific basis for the sustainable utilization of this valuable medicinal plant.

We demonstrated herein that ZnO nanoparticle with sizes in the range of 3–5 nm grown on the surface of halloysite nanotubes (HNTs) could be facile prepared in large quantities through the seed-mediated growth process using ZnAc 2 ·2H 2 O as the zinc source. Compared with the individually dispersed ZnO nanoparticles, the as-prepared HNTs@ZnO nanocomposites showed a smaller band gap energy and relatively strong light absorption. Therefore, HNTs@ZnO nanocomposites possessed higher photocatalytic activity than individually dispersed ZnO nanoparticles, exhibiting the HNTs@ZnO nanocomposites could be used as highly efficient photocatalysts. The HNTs@ZnO nanocomposites endowed HNTs special performance and improve the catalytic activity of ZnO, which originated from narrow band gap and chemical passivation induced by a negative fixed charge in the HNTs support.

Groundwater is an important source of water for human sustenance. The determination of groundwater quality at island sites is an urgent priority in China, but there are lacking systematic reports relating to them. Here, 63 groups of groundwater samples were collected and analyzed of Hainan Island. The groundwater in the study area is weakly alkaline, mainly comprising hard and soft freshwater. The predominant anions and cations are HCO 3 − , and Ca 2+ and Na + , respectively, and the main water chemistry types are HCO 3 –Cl–Na and HCO 3 –Cl–Na–Ca. The chemical evolution of groundwater is mainly affected by water–rock interactions, cation exchange, and human activity. The groundwater is mostly of high quality and, in most areas, is suitable for drinking and irrigation. Contrastingly, the water quality in the west of the island is relatively poor. The spatial distribution of the risk coefficient (HQ) is consistent with the spatial variation in the NO 3 − concentrations in the groundwater. Notably, there are unacceptable health risks for different groups of people, with infants having the greatest level of impact, followed by children, teenagers, and adults. This study provides a valuable reference for the development and utilization of groundwater resources, as well as the improvement of aquatic ecological conditions on Hainan Island and other island areas worldwide.

The superimposed effects of sea level rise caused by global warming and land subsidence seriously threaten the sustainable development of coastal cities. In recent years, an important coastal city in China, Zhuhai, has been suffering from severe and widespread land subsidence; however, the characteristics, triggers, and vulnerability assessment of ground subsidence in Zhuhai are still unclear. Therefore, we used the SBAS-InSAR technique to process 51 Sentinel-1A images to monitor the land subsidence in Zhuhai during the period from August 2016 to June 2019. The results showed that there was extensive land subsidence in the study area, with a maximum rate of −109.75 mm/yr. The surface had sequentially undergone a process of minor uplift and decline fluctuation, sharp settlement, and stable subsidence. The distribution and evolution of land subsidence were controlled by tectonic fractures and triggered by the thickness of soft soil, the intensity of groundwater development, and the seasonal changes of atmospheric precipitation. The comprehensive index method and the analytic hierarchy process were applied to derive extremely high subsidence vulnerability in several village communities and some traffic arteries in Zhuhai. Our research provides a theoretical basis for urban disaster prevention in Zhuhai and the construction planning of coastal cities around the world.

In the era of digital marketing, where consumers and enterprises frequently interact with each other, consumers hold different attitudes toward the different sources of information, including corporate social responsibility information. Negative corporate social responsibility can have direct impacts on corporate reputation. Choosing appropriate channels to publish the negative social responsibility information of enterprises in order to reduce the impact of these negative social events on corporate reputation is imperative for corporate image management. This research examines the differences in the impact of enterprise-generated content and -co-generated content on consumer attitudes using second-hand data analysis and then investigates how different information sources influence corporate reputation through empirical experiments. The results indicate that co-generated content performs better than other sources of information on corporate reputation, while professional user-generated content has the most negative impact. We further identify the external attribution as a mediation mechanism in the relationship between information sources and corporate reputation. The theoretical contributions and managerial implications of the research findings are discussed.

Urban roads connect multiple elements within the city, and the settlement problems of underground railways and above-ground road systems are widespread worldwide. Therefore, we take Zhuhai as an example to investigate the current status and short-term evolution of the coastal city road system settlement. We applied Sentinel-1A and based on the SBAS-InSAR, extracted the settlement information from 2016 to 2019. The results show that the road system settlement has a ‘three-ring’ interval, experiencing four stages: small rise and fall, linear plunge, large rise and fall, and stable settlement. The spatial characteristics of the settlement of highways, national highways, provincial highways, railways, and other types of single roads are manifested in the form of many prominent settlement segments, unequal horizontal extension distances, large vertical settlement variability, and a three-year cumulative settlement of −150 −100 mm at prominent settlement points. Road settlement is strongly influenced by the hydrogeological environment, and the tuning point of road deformation coincides with the timing of extreme meteorological events. The predictive modelling under the existing conditions shows a major settlement of −50 to −30 mm in the coming year, and the impacts will continue to deepen in the following years. This study provides a multi-level perspective on urban road settlement.

Background Meteorological factors and air pollutants have been reported to be associated with hand, foot, and mouth disease (HFMD) epidemics before the introduction of vaccine. However, there is limited evidence for studies with long-term dimensions. Methods We collected the daily HFMD counts, weather and air pollution data from 2014 to 2020 in Chengdu. Distributed lag non-linear models (DLNM) were used to assess the associations of meteorological factors and air pollutants on HFMD cases. Results From 2014–2020, high relative humidity and precipitation and extremely high and low levels of PM 10 , O 3 , SO 2 and CO increased the risk of HFMD. In pre-vaccination period, extreme high and low temperatures, PM 10 and NO 2 , low precipitation and high concentrations of PM 2.5 and O 3 significantly increase the risk of HFMD; In post-vaccination period, high relative humidity and low level of CO can significantly increase the incidence of HFMD; During the period of COVID-19, only low temperature will significantly increase the risk of HFMD; Low concentration of air pollutants has the greatest impact on the 6–14 age group, while the high concentration of air pollutants has the greatest impact on the 0–1 age group. Conclusions Our study suggest that high relative humidity and precipitation and extremely high and low levels of PM 10 , O 3 , SO 2 and CO increased the risk of HFMD from 2014 to 2020. The results of this study provide a reference for local authorities to formulate intervention measures and establish an environment-based disease early warning system.

PurposeThe increasing presence of traditional or new forms of robots at work demonstrates how the copresence of workers and robots might reframe work and workplaces and consequently arouse new human resource management (HRM) questions regarding how to manage the spatiotemporal change of work in organizations. Based on a spatiotemporal perspective, this conceptual article examines the implication of new spatiotemporal dynamics of work, which are generated by the interaction between workers and traditional or new forms of robots that are driven by advanced digital technologies, for HRM.Design/methodology/approachThe article begins by carrying out a selective review focusing on the studies that enhanced the comprehension of the digital-driven spatiotemporal dynamics of work. It then presents a spatiotemporal framework from which it examines the implications of digital-driven spatiotemporal work boundaries for HRM. The article ends by underscoring the theoretical and empirical importance of taking more interest in new spatiotemporal forms of work for developing the HRM of the future.FindingsBy developing the notion of workuniverses, which denotes the spatiotemporal boundaries generated by the act of working through the interaction between workers and different forms of robots, this research first develops a theoretical framework that discerns three forms of spatiotemporal dynamics forming workuniverses at different levels and two spatiotemporal arrays for managing the spatiotemporal change of work in organizations. The HRM questions and ethical concerns generated by the formation of workuniverses are then revealed through four focuses: the management ethics in workuniverses, individuals' spatiotemporal well-being, collective spatiotemporal coordination and spatiotemporal change management in workuniverses.Originality/valueThis research provides an original perspective, which is the spatiotemporal perspective, to examine the new spatiotemporal dynamics that form workuniverses and the HRM questions and concerns generated by the increasing interaction between workers and different forms of digital-driven robots.

Introduction: Cancer is a major health problem worldwide, and the most extensive treatment can be obtained by using chemotherapy in the clinic. However, due to the low selectivity of cancer cells, chemotherapy drugs produce a series of grievous side effects on normal cells. Methods: In this research, we developed novel nanocarriers for magnetically targeted near-infrared (NIR) light-electromagnetic wave dual controlled drug delivery based on MgFe2O4@CuS nanoparticles (NPs) modified with aminopropyltriethoxysilane (APTES) in response to magnetic, NIR light, and electromagnetic wave irradiation. Synthesis and characterization of MgFe2O4@CuS-APTES NPs was carried out using X-ray diffraction measurements, scanning electron microscopy, transmission electron microscopy, photoluminescence emission spectra, UV-1800 spectrophotometer, N5230A vector network analyzer, MDS-6 microwave sample preparation system, and superconducting quantum interference device. In addition to that mentioned above, we also explored many other sides, such as the drug-loading, drug-controlled release efficiency, elect99omagnetic wave thermal effect and photo-thermal effect. Results: The results showed that APTES-modified MgFe2O4@CuS NPs had 37% high drug-loading capacity and high electromagnetic wave thermal conversion ability and NIR-light thermal conversion ability. In addition, ibuprofen (IBU) release from the MgFe2O4@CuS-APTES-IBU depends on the electromagnetic wave (2.45 GHz) and 1060 nm NIR light irradiation. After five cycles, the drug-release percentage was 90% and 66% separately, and could be adjusted by the time and cycles times of electromagnetic wave and NIR light irritation. Electromagnetic wave irradiation compared with NIR light irradiation, has a higher drug release rate and better penetration. Therefore, choosing different stimulation methods according to the treatment needs of the disease, we can achieve accurate personalized treatment of the disease. Discussion: Our findings indicate that multifunctional APTES modified MgFe2O4@CuS NPs could be used for the first time as a new drug carrier for “location-timing-quantification” drug release with magnetic targeting and dual control of NIR light-electromagnetic waves.

Three inactivated enterovirus A71 (EV-A71) vaccines have been widely vaccinated among children in the targeted age group in mainland China since mid-2016. However, comprehensive virological surveillance of hand, foot and mouth disease (HFMD) over multiple years after the use of EV-A71 vaccines has rarely been conducted. Using long-term data extracted from the Public Health and Clinical Center of Chengdu, we described the clinical, aetiological, and epidemiological characteristics of HFMD inpatients after the use of EV-A71 vaccines from 2017 through 2022. A total of 5115 patients were selected for analysis with a male-to-female ratio of 1.63:1 and were mostly under 5 years of age (97.6%). Among these cases, 4.3% presented with severe symptoms, and 4.1% of severe cases experienced significant complications. EV-A71 was no longer the major serotype for laboratory-confirmed HFMD, responsible for 15.6% of severe cases and 1.2% of mild cases. A significant downwards trend of EV-A71 infections was observed after the use of EV-A71 vaccines (P for trend < 0.001). Coxsackievirus A6 was the predominant pathogen, accounting for 63.5% of mild cases and 36.2% of severe cases. Coxsackievirus A10 (CV-A10) and A16 were sporadically detected, and an upwards trend was observed in the proportion of CV-A10 infections. This study provides baseline molecular epidemiology for the evaluation of EV-A71 vaccination impact and potential serotype replacement based on HFMD inpatients. Additional nationwide and population-based epidemiologic and serologic studies are essential to elucidate HFMD dynamics after the use of EV-A71 vaccines, and to inform public health authorities to introduce optimized intervention strategies.