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The World Urban Database and Access Portal Tools (WUDAPT) is an international community-based initiative to acquire and disseminate climate relevant data on the physical geographies of cities for modeling and analysis purposes. The current lacuna of globally consistent information on cities is a major impediment to urban climate science toward informing and developing climate mitigation and adaptation strategies at urban scales. WUDAPT consists of a database and a portal system; its database is structured into a hierarchy representing different levels of detail, and the data are acquired using innovative protocols that utilize crowdsourcing approaches, Geowiki tools, freely accessible data, and building typology archetypes. The base level of information (L0) consists of local climate zone (LCZ) maps of cities; each LCZ category is associated with a range of values for model-relevant surface descriptors (roughness, impervious surface cover, roof area, building heights, etc.). Levels 1 (L1) and 2 (L2) will provide specific intra-urban values for other relevant descriptors at greater precision, such as data morphological forms, material composition data, and energy usage. This article describes the status of the WUDAPT project and demonstrates its potential value using observations and models. As a community-based project, other researchers are encouraged to participate to help create a global urban database of value to urban climate scientists.

Testosterone is a sex hormone involved in brain maturation via multiple molecular mechanisms. Previous human studies described age-related changes in the overall volume and structural properties of white matter during male puberty. Based on this work, we have proposed that testosterone may induce a radial growth of the axon and, possibly, modulate axonal transport. In order to determine whether this is the case we have used two different experimental approaches. With electron microscopy, we have evaluated sex differences in the structural properties of axons in the corpus callosum (splenium) of young rats, and tested consequences of castration carried out after weaning. Then we examined in vitro the effect of the non-aromatizable androgen Mibolerone on the structure and bidirectional transport of wheat-germ agglutinin vesicles in the axons of cultured sympathetic neurons. With electron microscopy, we found robust sex differences in axonal diameter (males>females) and g ratio (males>females). Removal of endogenous testosterone by castration was associated with lower axon diameter and lower g ratio in castrated (vs. intact) males. In vitro, Mibolerone influenced the axonal transport in a time- and dose-dependent manner, and increased the axon caliber as compared with vehicle-treated neurons. These findings are consistent with the role of testosterone in shaping the axon by regulating its radial growth, as predicted by the initial human studies. •In humans, volume and properties of white matter change during male adolescence.•Here we show that axons are thicker in male than female rats.•Castration at weaning eliminates this structural sex difference.•Synthetic testosterone affects axonal transport in vitro.

This paper presents a hierarchical conflation process applied to open datasets for the creation of a seamless pan-European map of building footprints in vector format, named Digital Building Stock Model – DBSM. The objective is the sequential addition of input components (which currently include OpenStreetMap, Microsoft GlobalML Building Footprints, European Settlement Map), taking into account their limitations, and aiming at the highest level of completeness possible, for planning and evaluating energy transition scenarios at the EU level. The results indicate how DBSM compares robustly against cadastral data from Estonia, used as reference area. The comparison of DBSM with GHS-BUILT-S, a 10 metres resolution grid with worldwide coverage that encodes the built-up surface in each pixel as derived from Sentinel-2 imagery for the year 2018, reveals a relative overestimation of the latter, factored by 0.68 at the EU scale for a sound match.

The rate of inelastic nuclear interactions in a short bent silicon crystal was precisely measured for the first time using a 180 GeV/c positive hadron beam produced in the North Experimental Area of the CERN SPS. An angular asymmetry dependence on the crystal orientation in the vicinity of the planar channeling minimum has been observed. For the inspected crystal, this probability is about ∼ 20 % larger than in the amorphous case because of the atomic density increase along the particle trajectories in the angular range of volume reflection, whose dimension is determined by the crystal bending angle. Instead, for the opposite angular orientation with respect to the planar channeling, there is a smaller probability excess of ∼ 4 % .

We present the experimental observation of the reduction of multiple scattering of high-energy positively charged particles during channeling in single crystals. According to our measurements the rms angle of multiple scattering in the plane orthogonal to the plane of the channeling is less than half that for non-channeled particles moving in the same crystal. In the experiment we use focusing bent single crystals. Such crystals have a variable thickness in the direction of beam propagation. This allows us to measure rms angles of scattering as a function of thickness for channeled and non-channeled particles. The behaviour with thickness of non-channeled particles is in agreement with expectations whereas the behaviour of channeled particles has unexpected features.

The Global Human Settlement Layer (GHSL) is supported by the European Commission, Joint Research Center (JRC) in the frame of his institutional research activities. Scope of GHSL is developing, testing and applying the technologies and analysis methods integrated in the JRC Global Human Settlement analysis platform for applications in support to global disaster risk reduction initiatives (DRR) and regional analysis in the frame of the European Cohesion policy. GHSL analysis platform uses geo-spatial data, primarily remotely sensed and population. GHSL also cooperates with the Group on Earth Observation on SB-04-Global Urban Observation and Information, and various international partners andWorld Bank and United Nations agencies. Some preliminary results integrating global human settlement information extracted from Landsat data records of the last 40 years and population data are presented.

Bunch merging is a well-established technique to increase the intensity of synchrotrons and the luminosity of circular colliders. We suggest to exploit a combination of channeling, volume reflection and amorphous interactions in a bent crystal for beam merging in a transfer line. Two beams converging into the bent crystal along special directions should emerge in almost parallel directions. A merging scenario is discussed, and data collected by the UA9 Collaboration are reprocessed to prove its feasibility. Comparison with magnetic stacking, which is a similar process, is presented.

The article is devoted to the study of the suppression of multiple scattering of positively charged particles with momenta of 180 GeV/c and 400 GeV/c passing through bent single crystals of silicon at small angles to the plane (111) both in channeling mode and in the above-barrier state. For the first time, the suppression of the effect of multiple scattering of non-channeling particles passing at a small angle to one of the planes of a silicon single crystal was observed. In addition, the asymmetry was observed in the multiple scattering of over-barrier particles with respect to their zero angle of entry into the single crystal.

Urban areas in sub-Saharan Africa are growing at an unprecedented pace. Much of this growth is taking place in informal settlements. In South Africa more than 10% of the population live in urban informal settlements. South Africa has established a National Informal Settlement Development Programme (NUSP) to respond to these challenges. This programme is designed to support the National Department of Human Settlement (NDHS) in its implementation of the Upgrading Informal Settlements Programme (UISP) with the objective of eventually upgrading all informal settlements in the country. Currently, the NDHS does not have access to an updated national dataset captured at the same scale using source data that can be used to understand the status of informal settlements in the country. This pilot study is developing a fully automated workflow for the wall-to-wall processing of SPOT-5 satellite imagery of South Africa. The workflow includes an automatic image information extraction based on multiscale textural and morphological image features extraction. The advanced image feature compression and optimization together with innovative learning and classification techniques allow a processing of the SPOT-5 images using the Landsat-based National Land Cover (NLC) of South Africa from the year 2000 as low-resolution thematic reference layers as. The workflow was tested on 42 SPOT scenes based on a stratified sampling. The derived building information was validated against a visually interpreted building point data set and produced an accuracy of 97 per cent. Given this positive result, is planned to process the most recent wall-to-wall coverage as well as the archived imagery available since 2007 in the near future.

Herculaneum, buried by Mount Vesuvius in AD 79, was only extensively excavated during the twentieth century, revealing a remarkable level of preservation but also fragility of what had survived of this Roman seaside town. By the turn of the century, the conservation challenges, paired with the limited capacity of the authorities to respond, was putting the archaeological site at risk. The Herculaneum Conservation Project (HCP), a public-private project underway since 2001, has helped turnaround this situation with the presence of an interdisciplinary team working all year round alongside the public authority, today the Archaeological Park of Herculaneum. With the site in a more stable condition, HCP's attention in the last ten years shifted to building up knowledge and competencies for the self-sufficiency of the Park authority in the face of core long-term management obligations. A new focus on conservation proposals that meet the site's needs but are suited to public tendering found its maximum expression in planning long-term site maintenance cycles. Through the voices of the practitioners involved, the paper recounts the resources and approaches that have been developed in this regard, in particular the specific GIS module that breaks down the archaeological site into the items to be maintained and their relative importance. This massive register of objects – walls, architraves, doors, frescoes, mosaics, etc. – is the backbone of the three-year maintenance cycles developed by HCP adopting an innovative procurement framework for co-sourcing services and works in Italy, the first of which is now being implemented by the Park. A web-based application accessible by operators on site allows real time transmission of monitoring data and records of site-works underway to the database and GIS platform, satisfying immediate administrative needs and quality controls but also delineating the scope of subsequent maintenance cycles. Technological and management tools, shaped by, and responsive to, the needs of the site and their users (the heritage practitioners involved), have been put at the service of the entire life cycle of programmed maintenance at an urban scale, both administrative and technical aspects. This is part of a wider upward spiral of management improvements for the long-term sustainability of this important archaeological site.