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"Peterson, Kristin"
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Unruly Souls
Amid growing digital activism to address gender-based violence, institutional racism, and homophobia in U.S. society, Unruly Souls explores the intersectional feminist activism among young people within Islam and Evangelical Christianity. These religious misfits—marginalized from traditional religious spaces due to their sexuality, gender, or race—employ the creative tactics of digital media in their work to seek justice and to display their fundamental equality in the eyes of God. Through an analysis of various digital projects from hip-hop music videos and Instagram accounts to Twitter hashtags and podcasts, Kristin Peterson argues that the hybrid, flexible, playful, and sensory nature of digital media facilitate intersectional feminist activism within and beyond religious communities. Drawing on work from queer theory, decolonial theory, and Black feminist theory, this study explores how those who have been marginalized are able to effectively deploy their disregarded status along with digital media tactics to cultivate empathetic communities for those recovering from religious trauma.
eBook
Diffusion Tensor and Volumetric Magnetic Resonance Measures as Biomarkers of Brain Damage in a Small Animal Model of HIV
There are currently no widely accepted neuro-HIV small animal models. We wanted to validate the HIV-1 Transgenic rat (Tg) as an appropriate neuro-HIV model and then establish in vivo imaging biomarkers of neuropathology, within this model, using MR structural and diffusion tensor imaging (DTI).
Young and middle-aged Tg and control rats were imaged using MRI. A subset of middle-aged animals underwent longitudinal repeat imaging six months later. Total brain volume (TBV), ventricular volume (VV) and parenchymal volume (PV = TBV-VV) were measured. Fractional anisotropy (FA) and mean diffusivity (MD) values of the corpus callosum (CC) were calculated from DTI data.
TBV and PV were smaller in Tg compared to control rats in young and middle-aged cohorts (p<0.0001). VV increased significantly (p = 0.005) over time in the longitudinal Tg cohort. There were lower FA (p<0.002) and higher MD (p<0.003) values in the CC of middle-aged Tg rats compared to age-matched controls. Longitudinally, MD significantly decreased over time in Tg rats (p<0.03) while it did not change significantly in the control cohort over the same period of time (p>0.05).
We detected brain volume loss in the Tg rat, probably due to astrocytic dysfunction/loss, loss of structural/axonal matrix and striatal neuronal loss as suggested by immunofluorescence. Increased MD and decreased FA in the CC probably reflect microstructural differences between the Tg and Control rats which could include increased extracellular space between white matter tracts, demyelination and axonal degeneration, among other pathologies. We believe that the Tg rat is an adequate model of neuropathology in HIV and that volumetric MR and DTI measures can be potentially used as biomarkers of disease progression.
Journal Article
Unruly Souls
Amid growing digital activism to address gender-based violence,
institutional racism, and homophobia in U.S. society, Unruly
Souls explores the intersectional feminist activism among
young people within Islam and Evangelical Christianity. These
religious misfits-marginalized from traditional religious spaces
due to their sexuality, gender, or race-employ the creative tactics
of digital media in their work to seek justice and to display their
fundamental equality in the eyes of God. Through an analysis of
various digital projects from hip-hop music videos and Instagram
accounts to Twitter hashtags and podcasts, Kristin Peterson argues
that the hybrid, flexible, playful, and sensory nature of digital
media facilitate intersectional feminist activism within and beyond
religious communities. Drawing on work from queer theory,
decolonial theory, and Black feminist theory, this study explores
how those who have been marginalized are able to effectively deploy
their disregarded status along with digital media tactics to
cultivate empathetic communities for those recovering from
religious trauma.
eBook
Simulated Evolution of Protein-Protein Interaction Networks with Realistic Topology
We model the evolution of eukaryotic protein-protein interaction (PPI) networks. In our model, PPI networks evolve by two known biological mechanisms: (1) Gene duplication, which is followed by rapid diversification of duplicate interactions. (2) Neofunctionalization, in which a mutation leads to a new interaction with some other protein. Since many interactions are due to simple surface compatibility, we hypothesize there is an increased likelihood of interacting with other proteins in the target protein's neighborhood. We find good agreement of the model on 10 different network properties compared to high-confidence experimental PPI networks in yeast, fruit flies, and humans. Key findings are: (1) PPI networks evolve modular structures, with no need to invoke particular selection pressures. (2) Proteins in cells have on average about 6 degrees of separation, similar to some social networks, such as human-communication and actor networks. (3) Unlike social networks, which have a shrinking diameter (degree of maximum separation) over time, PPI networks are predicted to grow in diameter. (4) The model indicates that evolutionarily old proteins should have higher connectivities and be more centrally embedded in their networks. This suggests a way in which present-day proteomics data could provide insights into biological evolution.
Journal Article
Beyond Fashion Tips and Hijab Tutorials: The Aesthetic Style of Islamic Lifestyle Videos
Among young women, lifestyle videos have become extremely popular on YouTube, and a similar trend has emerged among young Muslim women who share modest fashion tips and discuss religious topics. This paper examines the videos of two prominent Muslim women on YouTube, Amena Khan and Dina Torkia, in an effort to understand how they engage with aesthetic styles in order to work against Western stereotypes of Muslim women as oppressed and lacking individuality. Islamic lifestyle videos might appear to simply promote a vacuous focus on appearances, but I argue that it is through the aesthetics and affects of these videos that Amena and Dina do political work to redistribute the sensible and shift what is considered attractive, beautiful and pleasurable in Western society. Additionally, the hybrid aesthetic styles and affects of authenticity and pleasure, which are possible in digital spaces like YouTube, offer Amena and Dina the chance to control their own visual images and to resist being coopted as icons of Western freedom or Islamic piety.
Journal Article
SARS-CoV-2 and croup, not a rare coincidence
Dear Editor, We have read this series pertaining to croup and COVID-19, written by Venn and colleagues [1], as described through the cases of three children with presentations of croup as a result of SARS-CoV-2 infections. The only positive viral infection in the patient was SARS-CoV-2 by PCR. Within our review of children presenting with the traditional croup-like symptoms (“barky cough, stridor, dyspnea [3], we have at least three more cases, in addition to the four mentioned above, that were negative for other viruses and only positive for COVID-19 by PCR.
Journal Article
Cophylogeny and biogeography of the fungal parasite Cyttaria and its host Nothofagus, southern beech
The obligate, biotrophic association among species of the fungal genus Cyttaria and their hosts in the plant genus Nothofagus often is cited as a classic example of cophylogeny and is one of the few cases in which the biogeography of a fungus is commonly mentioned or included in biogeographic analyses. In this study molecular and morphological data are used to examine hypotheses regarding the cophylogeny and biogeography of the 12 species of Cyttaria and their hosts, the 11 species of Nothofagus subgenera Lophozonia and Nothofagus. Our results indicate highly significant overall cophylogenetic structure, despite the fact that the associations between species of Cyttaria and Nothofagus usually do not correspond in a simple one to one relationship. Two major lineages of Cyttaria are confined to a single Nothofagus subgenus, a specificity that might account for a minimum of two codivergences. We hypothesize other major codivergences. Numerous extinction also are assumed, as are an independent parasite divergence followed by host switching to account for C. berteroi. Considering the historical association of Cyttaria and Nothofagus, our hypothesis may support the vicariance hypothesis for the trans-Antarctic distribution between Australasian and South American species of Cyttaria species hosted by subgenus Lophozonia. It also supports the hypothesis of transoceanic long distance dispersal to account for the relatively recent relationship between Australian and New Zealand Cyttaria species, which we estimate to have occurred 44.6-28.5 mya. Thus the history of these organisms is not only a reflection of the breakup of Gondwana but also of other events that have contributed to the distributions of many other southern hemisphere plants and fungi.
Journal Article
HIV prevention clinical trials' community engagement guidelines: inequality, and ethical conflicts
In 2004 and 2005, the first clinical trials were launched to investigate the use of tenofovir for HIV prevention in Cambodia, Cameroon, Nigeria and Thailand. Controversies erupted over the ethical integrity of the research protocol. We reflect on the events that led to the controversies and identified that scientific and ethical concerns raised by members of local communities at each of these sites were erased by trialists, causing crisis that led to premature shut down the early PrEP trials. In the aftermath of these trials, the World Health Organisation, UNAIDS, and AVAC developed ethics guidelines intended to recognize the concerns as authentic, and developed guidelines to improve researchers' engagement of communities in biomedical HIV prevention trial design and implementation. Our findings suggest that the ethics guidelines are limited in its ability to address power inequalities that leads to voice erasures and non-recognition of local competencies. Rather the ethical documents enabled trialists to gain a new sense of authority through the interpretations of ethical research conduct enabling trialists regain power that can further entrench inequality and voice erasures. To address concerns with what seems an intractable problem, we suggested models of engagement for off-shored research may be the option.
Journal Article