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The mandible is a critical structure of the lower facial skeleton which plays an important role in several vital functions. Segmental resection of the mandible is at times required in patients with advanced oral cavity malignancies, primary mandibular tumors, and radiation or medication induced osteonecrosis. Mandibulectomy can significantly decrease quality of life, and thus mandibular reconstruction is an important aspect of the operative plan. Mandibular reconstruction is challenging due to the complex three‐dimensional anatomy of the mandible, and the precision required to restore dental occlusion in dentate patients. Significant advances have been made over the past decade in the ability to reconstruct and rehabilitate patients after a segmental mandibulectomy. This review will highlight these advances and discuss the timing of dental implantation.

Objective The “July effect,” a theory that the beginning of the academic year has worse operative outcomes and complication rates, remains controversial. We evaluated the “July effect” as a risk factor for negative operative outcomes in head and neck microvascular reconstruction. Methods Multi‐institutional retrospective review at three academic tertiary care centers from January 2010 to August 2021. Free flaps were stratified by the academic quarter. Patient factors, operative variables, length of stay (LOS), flap failures, and postoperative complications and adverse events were compared between academic quarters 1 and 4. Results We identified 2897 free flaps: 749 quarter 1 (Q1), 693 quarter 2 (Q2), 770 quarter 3 (Q3), and 685 quarter 4 (Q4). Overall flap failure rate was 4.9% (n = 143), and the most common postoperative complications were wound infection (12.8%, n = 370) and dehiscence (7.6%, n = 221). There were no significant differences between quarters in overall complication rate, flap failures, partial flap necrosis, wound infection, fistula, or hematoma (p > 0.05). There were also no significant differences in LOS or rates of 30‐day readmission or reoperation (p > 0.05). Q1 had significantly more dehiscences (p = 0.04) and longer operative times (p = 0.001) than Q4. Conclusion Although Q1 surgeries had significantly longer operative times and higher dehiscence rates, we found no other differences in postoperative complications, flap failures, or adverse events by the academic quarter. While a “July effect” may exist due to the integration of new trainees into the surgical workflow, this effect does not translate into meaningful differences in overall free flap or patient outcomes. Key points Significant findings of the study: Surgeries performed in the first quarter of the academic year have significantly longer operative times and higher dehiscence rates. We found no other differences in postoperative complications, flap failures, or adverse events by academic quarter. What this study adds: The July effect has been studied in a variety of medical specialties and procedures within otolaryngology. To date, no study has evaluated the impact of the “July effect” in otolaryngology at an institutional level; thus, our study aims to fill that gap in the literature to guide institutions as new surgical interns and fellows are integrated into the surgical workflow.

Purpose – The paper aims to present a device devoted to detect and measure earth displacements produced by landslides. This device is an inclinometer type geotechnical instrument. It is widely known that landslides are categorized among the most destructive disasters that yearly produce huge damages and even human lives losses. Design/methodology/approach – The principle of operation is based on measuring the deformation produced during soil layers sliding to a rod vertically mounted into the ground. The rod deformation is detected by highly sensitive strain gauges developed by authors using the stress impedance effect occurring in non-magnetostrictive magnetic amorphous microwires. The gauges are mounted in bridge configurations along the rod, beside the corresponding analogue and digital signal processing circuitry. Findings – The landslide transducer is able to calculate the displacement of the soil layers at different levels of depth and the direction of the landslide. It has been tested in laboratory in terms of sensitivity and accuracy. A resolution of less than 1 mm has been achieved for displacement detection, whereas orientation may be calculated with about a maximum accuracy of less than 20 degrees. Research limitations/implications – Problems occurred in the manufacturing process of the gauges because of the quite large dispersion of the microwire parameters, as well as with gluing the gauges on the rod, that is compulsory to be well done, otherwise the gauges relaxation occurs with consequence in time stability decay. Originality/value – With respect to other commercial devices, our inclinometer is characterized by high sensitivity and also by possibility of 3D measuring, it being able to gauge in depth the amplitude and orientation of the landslide.

The paper presents a study on the measurement stability of a landslide sensor based on four magnetic amorphous wire strain gauges used in an Wheatstone bridge configuration. The sensor is aimed for in-situ monitoring using a distributed sensor network. The experiment has been performed in the lab using a test stand, while a time step progressive deformation has been applied to the sensor. Results show a good stability of the measurement and a variable sensitivity with respect to the bending point.

The paper presents a device devoted to detect and measure earth displacements produced by landslides. It is part of inclinometer type geotechnical instruments and is based on measuring the deformation produced to a rod vertically mounted into the ground during soil layers sliding. With respect to other commercial devices, our inclinometer is characterized by high sensitivity to very small deformations owing to special strain gauges utilized in its construction, and also by possibility of 3D measuring, it being able to gauge in depth the amplitude and orientation of the soil layers displacement.

This paper focuses on the evaluation of a web-based application used in grant application evaluations, software developed in our university, and underlines the need for simple solutions, based on recent technology, specifically tailored to one's needs. We asked the reviewers to answer a short questionnaire, in order to assess their satisfaction with such a web-based grant application evaluation solution. All 20 reviewers accepted to answer the questionnaire, which contained 8 closed items (YES/NO answers) related to reviewer's previous experience in evaluating grant applications, previous use of such software solutions and his familiarity in using computer systems. The presented web-based application, evaluated by the users, shown a high level of acceptance and those respondents stated that they are willing to use such a solution in the future. [PUBLICATION ABSTRACT]

Stress hyperglycaemia is common in critical illness. We have previously observed that increasing severity of respiratory failure in patients with severe COVID-19 is associated with increased insulin demand. Given previously reported direct effects of hypoxia on insulin action, we reasoned that rapid improvements in oxygenation following prone positioning may improve insulin sensitivity and increase risk of hypoglycaemia. A retrospective multi-centre service evaluation comparing blood glucose and insulin administration in patients with COVID-19 pneumonitis receiving prone mechanical ventilation, comparing the 16 h pre-prone and 16 h post-prone time periods. 155 patients were included in this analysis. Oxygenation improved significantly following prone positioning (change in SpO 2 /FIO 2 per hour prone: 3.01 ± 0.14, P  < 0.0001). Glycaemic control was similar during the supine and prone study periods, and there were no hypoglycaemic events in the prone study period. Prone positioning was associated with an unexpected modest but significant increase in insulin requirements (mean difference in total insulin dose (IU): 8.32 ± 2.14, P  < 0.001) that was robust to several sensitivity analyses, and could not be explained by changes in carbohydrate intake. We did not observe an increased rate of hypoglycaemia during prone ventilation and the adequacy of glycaemic control was comparable during the supine and prone study periods. Unexpectedly, prone ventilation was associated with an increase in insulin requirements despite significant improvement in hypoxaemia. Our findings support the safety of prone ventilation with respect to glycaemic control and identify a novel relationship between ventilation position and insulin requirements in critical illness.

Acellular dermal matrices (ADMs) are widely used in soft-tissue reconstruction, yet the optimal timing for split-thickness skin grafting (STSG) remains unsettled. We conducted a single-center retrospective cohort study (January 2023–August 2025) of adults undergoing ADM-based reconstruction with Integra® Double Layer (IDL), Integra® Single Layer (ISL), or Nevelia®. Primary endpoints included length of stay (LOS), STSG requirement and timing, and in-hospital complications; secondary endpoints included spontaneous epithelialization. Prespecified adjusted analyses (linear/logistic models) controlled for age, sex, etiology, anatomical site, diabetes/PAOD, smoking, wound size (when available), wound contamination, and matrix type. Histology and immunohistochemistry (H&E, Masson trichrome, CD105, D2-40) assessed matrix integration and vascular/lymphatic maturation. Seventy-five patients were included (IDL n = 40; ISL n = 20; Nevelia n = 15). On multivariable analysis, matrix type was not an independent predictor of LOS (ISL vs. IDL β = +2.84 days, 95% CI −17.34 to +23.02; Nevelia vs. IDL β = −4.49 days, 95% CI −16.24 to +7.26). Complications were infrequent (6/75, 8.0%) and comparable across matrices; spontaneous epithelialization occurred in 3/75 patients (4.0%). A day-14 grafting strategy, applied only after documented clinical integration, was feasible in 30/75 (40.0%) patients without excess complications. Histology/IHC at 3–4 weeks demonstrated CD105-positive, perfused capillary networks with abundant collagen; at 4–6 weeks, D2-40-positive lymphatic structures confirmed progressive neo-dermis maturation, supporting the biological plausibility of earlier grafting once integration criteria are met. In this cohort, outcomes were broadly similar across matrices after adjustment. A criteria-based early STSG approach (~day 14) appears safe and operationally advantageous when integration is confirmed, while a minority of defects may heal without grafting. Prospective multicenter studies with standardized scar/functional measures and cost analyses are needed to refine patient selection and graft timing strategies.

With ultrafast laser systems reaching presently 10 PW peak power or operating at high repetition rates, research towards ensuring the long-term, trouble-free performance of all laser-exposed optical components is critical. Our work is focused on providing insight into the optical material behavior at fluences below the standardized laser-induced damage threshold (LIDT) value by implementing a simultaneous dual analysis of surface emitted particles using a Langmuir probe (LP) and the target current (TC). ${\\mathrm{HfO}}_2$ and ${\\mathrm{ZrO}}_2$ thin films deposited on fused silica substrates by pulsed laser deposition at various ${\\mathrm{O}}_2$ pressures for defect and stoichiometry control were irradiated by Gaussian, ultrashort laser pulses (800 nm, 10 Hz, 70 fs) in a wide range of fluences. Both TC and LP collected signals were in good agreement with the existing theoretical description of laser–matter interaction at an ultrashort time scale. Our approach for an in situ LIDT monitoring system provides measurable signals for below-threshold irradiation conditions that indicate the endurance limit of the optical surfaces in the single-shot energy scanning mode. The LIDT value extracted from the LP-TC system is in line with the multipulse statistical analysis done with ISO 21254-2:2011(E). The implementation of the LP and TC as on-shot diagnostic tools for optical components will have a significant impact on the reliability of next-generation ultrafast and high-power laser systems.

Background/Objectives: Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare and aggressive cutaneous lymphoma, often misdiagnosed due to nonspecific clinical features. Early diagnosis and treatment remain challenging. Methods: We report the case of a 31-year-old female with a chronic non-healing gluteal wound initially treated as an abscess. The lack of improvement prompted repeated investigations, culminating in the diagnosis of SPTCL with an alpha–beta T-cell phenotype. Results: Management involved combined chemotherapy and surgical wound reconstruction. Six cycles of CHOEP-21 chemotherapy led to complete clinical remission. A soft tissue defect superinfected with multidrug-resistant organisms was successfully reconstructed using Integra Dermal Regeneration Template followed by split-thickness skin grafting. Conclusions: This case highlights the diagnostic complexity of SPTCL and the therapeutic potential of dermal matrix application in complex wound management, especially in immuno-compromised patients.