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\"The two versions of Piccoli: a second edition of IS for Managers: Text and Cases and a first edition of a text only version, titled Essentials of IS for Managers offer an engaging, non-academic style and actionable frameworks to help readers develop value added IT-dependent strategic initiatives. The version with cases offers an \"all in one\" book for those who don't want to choose their own cases. Each case has extensive notes prepared by the author to help teach a meaningful course. Part III on \"The Strategic use of IS\" offers unique and useful frameworks that MBAs will be able to put into practice. \"-- Provided by publisher.

This paper responds to the recent call for understanding the nature and consequences of the digital mediation of everyday experiences. We do so in the context of online opinion sharing. We propose that the unique design features of mobile computing devices and the intention and purpose of their users, meld into a technology affordance we label: Triggered essential reviewing. We empirically investigate the effect of this technology affordance on opinion characteristics (i.e., timing and length), and outcomes (i.e., opinion valence and content). We find that triggered essential reviewing engenders opinions that cover a narrower range of aspects of the experience and that it produces a negative evaluative bias-a bias that mitigates over time. Our work makes two contributions to the application of affordance theory in Information Systems. First, it shows the importance of IT design in studying experiential computing. While not taking a deterministic view of technology, we validate the notion that different technology designs produce a variation of effects around a predictable central tendency. Second, it empirically demonstrates that the affordances of embodied digital experiences have an effect on actual behavior as well as on the outcome of the experience itself.

Background To report the first Italian case of hypotrichosis with juvenile macular dystrophy complicated by macular neovascularization diagnosed through multimodal imaging. Case presentation An 11-year-old boy was referred to our Institution for bilateral maculopathy of unknown origin. Multimodal imaging helps the diagnosis of Juvenile Macular Dystrophy with Hypotrichosis (HJMD). Fundus examination showed several alterations of the retinal pigment epithelium and circular pigmented area of chorioretinal atrophy. Structural spectral domain optical coherence tomography (OCT) showed some backscattering phenomenon with several alterations of retinal pigment epithelium and photoreceptor layer in both eyes. Moreover, OCT showed hyperreflective lesion beneath the neuroepithelium in left eye. OCT angiography (OCT-A) revealed a pathologic neovascular network in choriocapillaris plexus, probably the result of a fibrovascular membrane. Multifocal electroretinograms (MfERGs) showed functional alterations in 12.22° of the central retina. In order to confirm the suspicion of HJMD, the child and both parents underwent genetic testing. Both parents resulted to be heterozygous healthy carriers of a single variation. Conclusion Multimodal imaging, in particular OCT-A, is a useful aid, along to clinical findings and genetics, for the diagnosis of inherited retinal dystrophies.

The role of information systems in the creation and appropriation of economic value has a long tradition of research, within which falls the literature on the sustainability of IT-dependent competitive advantage. In this article, we formally define the notion of IT-dependent strategic initiative and use it to frame a review of the literature on the sustainability of competitive advantage rooted in information systems use. We offer a framework that articulates both the dynamic approach to IT-dependent strategic advantage currently receiving attention in the literature and the underlying drivers of sustainability. This framework models how and why the characteristics of the IT-dependent strategic initiative enable sustained competitive advantage, and how the determinants of sustainability are developed and strengthened over time. Such explanation facilitates the pre-implementation analysis of planned initiatives by innovators, as well as the post-implementation evaluation of existing initiatives so as to identify the basis of their sustainability. In carrying out this study, we examined the interdisciplinary literature on strategic information systems. Using a structured methodology, we reviewed the titles and abstracts of 648 articles drawn from information systems, strategic management, and marketing literature. We then examined and individually coded a relevant subset of 117 articles. The literature has identified four barriers to erosion of competitive advantage for IT-dependent strategic initiatives and has surfaced the structural determinants of their magnitude. Previous work has also begun to theorize about the process by which these barriers to erosion evolve over time. Our review reveals that significant exploratory research and theoretical development have occurred in this area, but there is a paucity of research providing rigorous tests of theoretical propositions. Our work makes three principal contributions. First, it formalizes the definition of IT-dependent strategic initiative. Second, it organizes the extant interdisciplinary research around an integrative framework that should prove useful to both research and practice. This framework offers an explanation of how and why IT-dependent strategic initiatives contribute to sustained competitive advantage, and explains the process by which they evolve over time. Finally, our review and analysis of the literature offers the basis for future research directions.

IntroductionA novel treatment for posterior blepharitis which involves the use of disposable wet wipes imbibed with a solution of terpinen-4-ol and hyaluronic acid (Hy-Ter®) as well as aloe, natural anti-inflammatories and antiseptics (Blephapad Combo; Novelty Technology Care, Milan, Italy) has been proposed. The aim of this study was to compare the efficacy and safety of treatment with Blephapad Combo with standard treatment.MethodsWe conducted 4-week, open-label, randomized controlled study with a closed sequential design at the Magna Graecia University of Catanzaro, Italy in which patients aged > 40 years with symmetrical bilateral posterior blepharitis were enrolled. Each eye represented a single experimental unit. Patients were randomly assigned using a computer-generated randomization list to apply a reusable heated compress to the eyelid of one eye before cleansing the eyelid with the Blephapad Combo wet wipe (Blephapad Combo treatment arm) or to use the standard treatment of applying a wet and warm gauze to the other eye (standard treatment arm), twice daily for 4 weeks. The primary endpoint was the percentage change from baseline to week 4 in meibomian gland dysfunction (MGD) grading scale scores.ResultsEighteen patients (9 men; 9 women) with a mean (± standard deviation) age of 66.9 ± 9.03 years were included in the study. Compared with the eye receiving the standard treatment, treatment with Blephapad Combo appeared to improve the MGD total score after 4 weeks of treatment (mean change from baseline − 29.9 vs. − 38.5%). The assessment of the investigators was that in 11 patients the eye treated with Blephapad Combo showed greater benefit, in two patients the eye treated with the standard treatment showed greater benefit and in four patients there was no difference between treatments. Blephapad Combo was well tolerated, with no serious adverse events (AEs) reported. Minor ocular AEs were reported in 44.4 and 38.9% of patients in the Blephard Combo and standard treatment arms, respectively.ConclusionsTreatment with Blephapad Combo was more effective than the standard treatment in ameliorating MGD in patients with posterior blepharitis. Minor ocular AEs events were equally distributed between the two treatments arms.Trial RegistrationClinicalTrials.gov identifier: NCT03301844.

The paucity of rigorous evaluation measures undermines topic modeling results’ validity and trustworthiness. Accordingly, we propose a method that researchers can use to select models when they assess topics’ human interpretability. We show how they can evaluate different topic models using gold-standard sets that humans label. Our approach ensures that the topics extracted algorithmically from an entire corpus concur with the themes humans would have identified in the same documents. By doing so, we combine human coding’s advantages for topic interpretability with algorithmic topic Modeling’s analytical efficiency and scalability. We demonstrate that one can rigorously identify optimal model parametrizations for maximum interpretability and to rigorously justify model selection. We also contribute three open access gold-standard sets in the hospitality context and make them available so other researchers can use them to benchmark their models or validate their results. Finally, we showcase a methodology for designing and developing gold-standard sets for validating topic models, which researchers interested in developing gold-standard sets in domains and contexts appropriate for their research can use.

In the year 2004 Portale Sardegna, an Italian online tour operator, launched a new product, Open Voucher (OV), with the bold objective of prolonging the tourist season on the island. The idea was conceptually simple: to create a Sardinian tourist product capable of attracting travelers to the island during the low season, while the implementation was quite difficult. Open Voucher attempted this de-seasonalization through the development of an Internet-enabled network of affiliated hotels providing availability of rooms year round and offering their product through the Open Voucher platform at a low, fixed rate. In the years ranging from 2004 to 2006, Open Voucher showed good traction in the marketplace, but in 2007 it began to record falling bookings and deteriorating results. What was happening? Had the leadership team defined the strategy to launch Open Voucher properly? Was it even possible to re-launch the Open Voucher product?

Information technology is providing the infrastructure necessary to support the development of new organizational forms. Virtual teams represent one such organizational form, one that could revolutionize the workplace and provide organizations with unprecedented levels of flexibility and responsiveness. As the technological infrastructure necessary to support virtual teams is now readily available, further research on the range of issues surrounding virtual teams is required if we are to learn how to manage them effectively. While the findings of team research in the traditional environment may provide useful pointers, the idiosyncratic structural and contextual issues surrounding virtual teams call for specific research attention.This article provides a review of previously published work and reports on the findings from early virtual team research in an effort to take stock of the current state of the art. The review is organized around the input - process - output model and categorizes the literature into issues pertaining to inputs, socio-emotional processes, task processes, and outputs. Building on this review we critically evaluate virtual team research and develop research questions that can guide future inquiry in this fertile are of inquiry.

This article reports the findings of a longitudinal study of temporary virtual teams and explores the role of behavior control on trust decline. We conducted an experiment involving 51 temporary virtual teams. Half of the teams were required to comply with behavior control mechanisms traditionally used in colocated teams. Their counterparts were allowed to self-direct. Our analysis shows that the behavior control mechanisms typically used in traditional teams have a significant negative effect on trust in virtual teams. In-depth analysis of the communication logs of selected teams reveals that trust decline in virtual teams is rooted in instances of reneging and incongruence. Behavior control mechanisms increase vigilance and make instances when individuals perceive team members to have failed to uphold their obligations (i.e., reneging and incongruence) salient. Heightened vigilance and salience increase the likelihood that team members' failure to fulfill their obligations will be detected, thus contributing to trust decline.