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153,980 result(s) for "Porter, T A"
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The man behind the bow tie : Arthur Porter on business, politics and intrigue
Arthur Porter tells his own story, beginning with his boyhood in Sierra Leone, his rise through the medical, corporate and political arenas in Canada, through to the confines of La Joya Prison where he is detained on charges of fraud.
A population of gamma-ray millisecond pulsars seen with the Fermi Large Area Telescope
Pulsars are born with subsecond spin periods and slow by electromagnetic braking for several tens of millions of years, when detectable radiation ceases. A second life can occur for neutron stars in binary systems. They can acquire mass and angular momentum from their companions, to be spun up to millisecond periods and begin radiating again. We searched Fermi Large Area Telescope data for pulsations from all known millisecond pulsars (MSPs) outside of globular clusters, using rotation parameters from radio telescopes. Strong gamma-ray pulsations were detected for eight MSPs. The gamma-ray pulse profiles and spectral properties resemble those of young gamma-ray pulsars. The basic emission mechanism seems to be the same for MSPs and young pulsars, with the emission originating in regions far from the neutron star surface.
Brachytherapy for prostate cancer
New methods of brachytherapy based on improved technology and an increased understanding of radiobiology hold promise for improving results in treating prostate cancer. The methods of prostate brachytherapy are examined.
Topical Application of WR-2721 Achieves High Concentrations in the Rectal Wall
Rectal wall injury is an important treatment-related morbidity in patients treated with radiation for prostate cancer. We have undertaken this study to investigate the merits of topical intrarectal application of the radioprotective compound WR-2721. Male Copenhagen rats were injected intrarectally with 2% WR-2721 gel. At 10, 20, 30 and 40 min after application, a laparotomy was performed, and the rectum and prostate were removed. Concentrations of total WR-1065 (the active metabolite of WR-2721) were determined in these samples by an HPLC assay. While the concentration in the rectal wall tended to increase with time, it did not change substantially in the prostate. The concentration in the rectal wall was found to be significantly higher at all times. We conclude that preferential accumulation of WR-2721 in the rectal wall can be achieved by topical application. This is a promising approach to modifying rectal wall tolerance that deserves more study.
The Steady-State Multi-TeV Diffuse Gamma-Ray Emission Predicted with GALPROP and Prospects for the Cherenkov Telescope Array
Cosmic Rays (CRs) interact with the diffuse gas, radiation, and magnetic fields in the interstellar medium (ISM) to produce electromagnetic emissions that are a significant component of the all-sky flux across a broad wavelength range. The Fermi Large Area Telescope (LAT) has measured these emissions at GeV \\(\\)-ray energies with high statistics. Meanwhile, the High-Energy Stereoscopic System (H.E.S.S.) telescope array has observed large-scale Galactic diffuse emission in the TeV \\(\\)-ray energy range. The emissions observed at GeV and TeV energies are connected by the common origin of the CR particles injected by the sources, but the energy dependence of the mixture from the general ISM (true `diffuse'), those emanating from the relatively nearby interstellar space about the sources, and the sources themselves, is not well understood. In this paper, we investigate predictions of the broadband emissions using the GALPROP code over a grid of steady-state 3D models that include variations over CR sources, and other ISM target distributions. We compare, in particular, the model predictions in the VHE (\\(\\)100 GeV) \\(\\)-ray range with the H.E.S.S. Galactic plane survey (HGPS) after carefully subtracting emission from catalogued \\(\\)-ray sources. Accounting for the unresolved source contribution, and the systematic uncertainty of the HGPS, we find that the GALPROP model predictions agree with lower estimates for the HGPS source-subtracted diffuse flux. We discuss the implications of the modelling results for interpretation of data from the next generation Cherenkov Telescope Array (CTA).
Periodic Gamma-ray Modulation of the blazar PG 1553+113 Confirmed by Fermi-LAT and Multi-wavelength Observations
A 2.1-year periodic oscillation of the gamma-ray flux from the blazar PG 1553+113 has previously been tentatively identified in almost 7 year of data from the Fermi Large Area Telescope. After 15 years of Fermi sky-survey observations, doubling the total time range, we report >7 cycle gamma-ray modulation with an estimated significance of 4 sigma against stochastic red noise. Independent determinations of oscillation period and phase in the earlier and the new data are in close agreement (chance probability <0.01). Pulse timing over the full light curve is also consistent with a coherent periodicity. Multiwavelength new data from Swift X-Ray Telescope, Burst Alert Telescope, and UVOT, and from KAIT, Catalina Sky Survey, All-Sky Automated Survey for Supernovae, and Owens Valley Radio Observatory ground-based observatories as well as archival Rossi X-Ray Timing Explorer satellite-All Sky Monitor data, published optical data of Tuorla, and optical historical Harvard plates data are included in our work. Optical and radio light curves show clear correlations with the gamma-ray modulation, possibly with a nonconstant time lag for the radio flux. We interpret the gamma-ray periodicity as possibly arising from a pulsational accretion flow in a sub-parsec binary supermassive black hole system of elevated mass ratio, with orbital modulation of the supplied material and energy in the jet. Other astrophysical scenarios introduced include instabilities, disk and jet precession, rotation or nutation, and perturbations by massive stars or intermediate-mass black holes in polar orbit.
Detection of 16 Gamma-Ray Pulsars Through Blind Frequency Searches Using the Fermi LAT
Pulsars are rapidly rotating, highly magnetized neutron stars emitting radiation across the electromagnetic spectrum. Although there are more than 1800 known radio pulsars, until recently only seven were observed to pulse in gamma rays, and these were all discovered at other wavelengths. The Fermi Large Area Telescope (LAT) makes it possible to pinpoint neutron stars through their gamma-ray pulsations. We report the detection of 16 gamma-ray pulsars in blind frequency searches using the LAT. Most of these pulsars are coincident with previously unidentified gamma-ray sources, and many are associated with supernova remnants. Direct detection of gamma-ray pulsars enables studies of emission mechanisms, population statistics, and the energetics of pulsar wind nebulae and supernova remnants.
High-energy emission from a magnetar giant flare in the Sculptor galaxy
Magnetars are the most highly magnetized neutron stars in the cosmos (with magnetic field 10 13 –10 15 G). Giant flares from magnetars are rare, short-duration (about 0.1 s) bursts of hard X-rays and soft γ rays 1 , 2 . Owing to the limited sensitivity and energy coverage of previous telescopes, no magnetar giant flare has been detected at gigaelectronvolt (GeV) energies. Here, we report the discovery of GeV emission from a magnetar giant flare on 15 April 2020 (refs. 3 , 4 and A. J. Castro-Tirado et al., manuscript in preparation). The Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope detected GeV γ rays from 19 s until 284 s after the initial detection of a signal in the megaelectronvolt (MeV) band. Our analysis shows that these γ rays are spatially associated with the nearby (3.5 megaparsecs) Sculptor galaxy and are unlikely to originate from a cosmological γ-ray burst. Thus, we infer that the γ rays originated with the magnetar giant flare in Sculptor. We suggest that the GeV signal is generated by an ultra-relativistic outflow that first radiates the prompt MeV-band photons, and then deposits its energy far from the stellar magnetosphere. After a propagation delay, the outflow interacts with environmental gas and produces shock waves that accelerate electrons to very high energies; these electrons then emit GeV γ rays as optically thin synchrotron radiation. This observation implies that a relativistic outflow is associated with the magnetar giant flare, and suggests the possibility that magnetars can power some short γ-ray bursts. Gigaelectronvolt emission from a magnetar giant flare is discovered by the Fermi Gamma-ray Space Telescope, between 19 s and 284 s after the initial detection of a signal in the megaelectronvolt energy band, potentially generated by an ultra-relativistic outflow far from the stellar magnetosphere.
Gamma-Ray emission from the shell of supernova remnant W44 revealed by the Fermi LAT
Recent observations of supernova remnants (SNRs) hint that they accelerate cosmic rays to energies close to ~1015 electron volts. However, the nature of the particles that produce the emission remains ambiguous. We report observations of SNR W44 with the Fermi Large Area Telescope at energies between 2 × 108 electron volts and 3 ×1011 electron volts. The detection of a source with a morphology corresponding to the SNR shell implies that the emission is produced by particles accelerated there. The gamma-ray spectrum is well modeled with emission from protons and nuclei. Its steepening above ~109 electron volts provides a probe with which to study how particle acceleration responds to environmental effects such as shock propagation in dense clouds and how accelerated particles are released into interstellar space