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We compared convolutional neural networks to the classical boosted decision trees for the separation of atmospheric particle showers generated by gamma rays from the particle-induced background. We conduct the comparison of the two techniques applied to simulated observation data from the Cherenkov Telescope Array. We then looked at the Receiver Operating Characteristics (ROC) curves produced by the two approaches and discuss the similarities and differences between both. We found that neural networks overperformed classical techniques under specific conditions.

The Intensity Interferometry technique consists of measuring the spatial coherence (visibility) of an object via its intensity fluctuations over a sufficient range of telescope separations (baselines). This allows us to study the size, shape and morphology of stars with an unprecedented resolution. Cherenkov telescopes have a set of characteristics that coincidentally allow for Intensity Interferometry observations: very large reflective surfaces, sensitivity to individual photons, temporal resolution of nanoseconds and the fact that they come in groups of several telescopes. In the recent years, the MAGIC Collaboration has developed a deadtime-free Intensity Interferometry setup for its two 17 m diameter Cherenkov telescopes that includes a 4-channel GPU-based real-time correlator, 410–430 nm filters and new ways of splitting its primary mirrors into submirrors using Active Mirror Control (AMC). With this setup, MAGIC can operate as a long-baseline optical interferometer in the baseline range 40–90 m, which translates into angular resolutions of 0.5-1 mas. Additionally, thanks to its AMC, it can simultaneously measure the zero-baseline correlation or, by splitting into submirrors, access shorter baselines under 17 m in multiple u-v plane orientations. The best candidates to observe with this technique are relatively small and bright stars, in other words, massive stars (O, B and A types). We will present the science cases that are currently being proposed for this setup, as well as the prospects for the future of the system and technique, like the possibility of large-scale implementation with CTA.

Levels of uncoupling protein-2 (UCP2) are regulated in the pancreatic beta cells and an increase in the protein level has been associated with mitochondrial uncoupling and alteration in glucose-stimulated insulin secretion. However, it is not clear whether an increase in uncoupling protein-2 per se induces mitochondrial uncoupling and affects ATP generation and insulin secretion. Transgenic mice with beta cell-specific overexpression of the human UCP2 gene and INS-1 cells with doxycycline-inducible overproduction of the protein were generated and the consequences of increased levels of UCP2 on glucose-induced insulin secretion and on parameters reflecting mitochondrial uncoupling were determined. In transgenic mice, an increase in beta cell UCP2 protein concentration did not significantly modify plasma glucose and insulin levels. Glucose-induced insulin secretion and elevation in the ATP/ADP ratio were unaltered by an increase in UCP2 level. In INS-1 cells, a similar increase in UCP2 level did not modify glucose-induced insulin secretion, cytosolic ATP and ATP/ADP ratio, or glucose oxidation. Increased levels of UCP2 did not modify the mitochondrial membrane potential and oxygen consumption. Increased UCP2 levels decreased cytokine-induced production of reactive oxygen species. The results obtained in transgenic mice and in the beta cell line do not support the hypothesis that an increase in UCP2 protein per se uncouples the mitochondria and decreases glucose-induced insulin secretion. In contrast, the observation that increased UCP2 levels decrease cytokine-induced production of reactive oxygen species indicates a potential protective effect of the protein on beta cells, as observed in other cell types.

3C 273 is one of the brightest and best studied quasars. It has been observed for 770 ks with the imager IBIS (FoV 12 deg) on board INTEGRAL. To achieve the best possible S/N the dataset has been screened using several criteria indicating the quality of the data (i.e., number of good time intervals, etc). We describe the necessary tools and methods to analyze data of deep fields.

Capella is the brightest chromospherically active binary in the sky, hosting a cooler G8III giant (Aa) and an hotter G1III companion (Ab). The source has been extensively observed in the X-rays in the past decades not only for its astrophysical interest in the field of corona sources, but also for in-flight calibrations of space-based X-ray instruments. In 2006, it was demonstrated using Chandra/HETG observations that Aa is the main contributor to Capella's X-ray emission, as the centroid energies of the emission lines are Doppler shifted along the orbit of the G8III giant (an aspect that has to be taken in consideration for calibration activities of X-ray instruments). In this paper, we extend the previous analysis performed in 2006 by re-analyzing in an homogeneous way all Chandra/HETG observations performed in the direction of Capella. By doubling the amount of data available, we strengthened the conclusion that Capella Aa is the dominant emitter in soft X-rays. We did not find any evidence of a statistically significant contribution to this emission by the Ab giant. Our findings are discussed also in light of the incoming launch of the XRISM mission (spring 2023).

A new generation of optical intensity interferometers are emerging in recent years taking advantage of the existing infrastructure of Imaging Atmospheric Cherenkov Telescopes (IACTs). The MAGIC SII (Stellar Intensity Interferometer) in La Palma, Spain, has been operating since its first successful measurements in 2019 and its current design allows it to operate regularly. The current setup is ready to follow up on bright optical transients, as changing from regular gamma-ray observations to SII mode can be done in a matter of minutes. A paper studying the system performance, first measurements and future upgrades has been recently published. MAGIC SII's first scientific results are the measurement of the angular size of 22 stars, 13 of which with no previous measurements in the B band. More recently the Large Sized Telescope prototype from the Cherenkov Telescope Array Observatory (CTAOLST1) has been upgraded to operate together with MAGIC as a SII, leading to its first correlation measurements at the beginning of 2024. MAGIC+CTAO-LST1 SII will be further upgraded by adding the remaining CTAOLSTs at the north site to the system (which are foreseen to be built by the end of 2025). MAGIC+CTAO-LST1 SII shows a feasible technical solution to extend SII to the whole CTAO.

The two MAGIC 17-m diameter Imaging Atmospheric Cherenkov Telescopes have been equipped to work also as an intensity interferometer with a deadtime-free, 4-channel, GPU-based, real-time correlator. Operating with baselines between approx. 40 and 90 m the MAGIC interferometer is able to measure stellar diameters of 0.5-1 mas in the 400-440 nm wavelength range with a sensitivity roughly 10 times better than that achieved in the 1970s by the Narrabri Stellar Intensity Interferometer. Besides, active mirror control allows to split the primary mirrors into sub-mirrors. This allows to make simultaneous calibration measurements of the zero-baseline correlation or to simultaneously collect six baselines below 17 m with almost arbitrary orientation, corresponding to angular scales of approx. 1-50 mas. We plan to perform test observations adding the nearby Cherenkov Telescope Array (CTA) LST-1 23 m diameter telescope by next year. All three telescope pairs will be correlated simultaneously. Adding LST-1 is expected to increase the sensitivity by at least 1 mag and significantly improve the u-v plane coverage. If successful, the proposed correlator setup is scalable enough to be implemented to the full CTA arrays.

Despite over 50 years of Gamma-Ray Burst (GRB) observations many open questions remain about their nature and the environments in which the emission takes place. Polarization measurements of the GRB prompt emission have long been theorized to be able to answer most of these questions. The POLAR detector was a dedicated GRB polarimeter developed by a Swiss, Chinese and Polish collaboration. The instrument was launched, together with the second Chinese Space Lab, the Tiangong-2, in September 2016 after which it took 6 months of scientific data. During this period POLAR detected 55 GRBs as well as several pulsars. From the analysis of the GRB polarization catalog we see that the prompt emission is lowly polarized or fully unpolarized. There is, however, the caveat that within single pulses there are strong hints of an evolving polarization angle which washes out the polarization degree in the time integrated analysis. Building on the success of the POLAR mission, the POLAR-2 instrument is currently under development. POLAR-2 is a Swiss, Chinese, Polish and German collaboration and was recently approved for launch in 2024. Thanks to its large sensitivity POLAR-2 will produce polarization measurements of at least 50 GRBs per year with a precision equal or higher than the best results published by POLAR. POLAR-2 thereby aims to make the prompt polarization a standard observable and produce catalogs of the gamma-ray polarization of GRBs. Here we will present an overview of the POLAR mission and all its scientific measurement results. Additionally, we will present an overview of the future POLAR-2 mission, and how it will answer some of the questions raised by the POLAR results.

Despite several decades of multi-wavelength and multi-messenger spectral observations, Gamma-Ray Bursts (GRBs) remain one of the big mysteries of modern astrophysics. Polarization measurements are essential to gain a more clear and complete picture of the emission processes at work in these extremely powerful transient events. In this regard, a first generation of dedicated gamma-ray polarimeters, POLAR and GAP, were launched into space in the last decade. After 6 months of operation, the POLAR mission detected 55 GRBs, among which 14 have been analyzed in detail, reporting a low polarization degree and a hint of a temporal evolution of the polarization angle. Starting early 2024 and based on the legacy of the POLAR results, the POLAR-2 instrument will aim to provide a catalog of high quality measurements of the energy and temporal evolution of the GRB polarization thanks to its large and efficient polarimeter. Several spectrometer modules will additionally allow to perform joint spectral and polarization analyzes. The mission is foreseen to make high precision polarization measurements of about 50 GRBs every year on board of the China Space Station (CSS). The technical design of the polarimeter modules will be discussed in detail, as well as the expected scientific performances based on the first results of the developed prototype modules.

The prompt emission of GRBs has been investigated for more than 50 years but remains poorly understood. Commonly, spectral and temporal profiles of -ray emission are analysed. However, they are insufficient for a complete picture on GRB-related physics. The addition of polarization measurements provides invaluable information towards the understanding of these astrophysical sources. In recent years, dedicated polarimeters, such as POLAR and GAP, were built. The former of which observed low levels of polarization as well as a temporal evolution of the polarization angle. It was understood that a larger sample of GRB polarization measurements and time resolved studies are necessary to constrain theoretical models. The POLAR-2 mission aims to address this by increasing the effective area by an order of magnitude compared to POLAR. POLAR-2 is manifested for launch on board the China Space Station in 2024 and will operate for at least 2 years. Insight from POLAR will aid in the improvement of the overall POLAR-2 design. Major improvements (compared to POLAR) will include the replacement of multi-anode PMTs (MAPMTs) with SiPMs, increase in sensitive volume and further technological upgrades. POLAR-2 is projected to measure about 50 GRBs per year with equal or better quality compared to the best seen by POLAR. The instrument design, preliminary results and anticipated scientific potential of this mission will be discussed.