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Laboratory tests were conducted on innovatively designed corrugated board packaging under random vertical vibrations. The innovative designs had reinforced critical corner zones and lid–base interfaces through geometry modifications that increased double-wall regions. A total of 25 packaging variants, differentiated in structure, layer configuration (three-layer and five-layer boards), and surface finish (with and without coatings) were evaluated. The experimental study included box compression tests (BCT) and random vibration tests according to international standards (ISO 12048:1994 and ISO 13355:2016), simulating storage and transportation conditions. All packages were assessed before and after random vibration tests to determine the influence of dynamic loads on structural load-bearing capacity. Unlike previous studies limited to static testing, this work evaluated combined vibration and compression effects under standardized dynamic loading conditions for packaging with relatively low probability of being dropped. Furthermore, it was shown that the innovative design of corrugated board transport packaging presents higher static load capacity after random vibration testing in terms of column compression strength, indicating that no reduction in box strength was observed during simplified transport simulation under pure one-direction dynamic loading. The findings contribute to the optimization of high-durability packaging solutions tailored for the growing demands of complex logistics chains.

Background Nitric oxide (NO) is involved in eating behavior and inflammatory response. Moreover, there is evidence that NO production is altered in patients with anorexia nervosa (AN). Aim To assess whether the overproduction of NO in AN can affect NO level in exhaled air. Materials and methods Exhaled NO level was studied in 23 girls with AN and compared with that of healthy age- and gender-matched nonatopic controls. Results Exhaled NO levels were significantly higher in girls with AN compared with healthy age-matched controls. Conclusions It appears that anorexia nervosa was accompanied by a higher level of exhaled NO, likely resulting from a systemic increase in NO production because of the severe catabolic state.