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"RUIZ, JORGE"
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Job-Boj
\"Written in alternating voices, Jorge Guzman's JOB BOJ is a captivating novel that explores the progression from melancholy to happiness, or vice versa. The delicate interplay between a light-hearted narrator and a brooding, introspective one draws the reader in to question identity. Are they the same man? Two different periods from the same life? Or are they two separate people? The reader is left to judge. While the novel is a superb masterclass in structure and innovation, JOB BOJ is a \"rich and absorbing entertainment.\") -- Provided by publisher.
Book
Food-Derived Antihypertensive Peptides: Mechanisms, Multi-Methodological Approaches, Bioavailability, and Functional Food Applications
This systematic review was conducted and reported according to the PRISMA 2020 statement to synthesize evidence published between January 2020 and January 2025 on food-derived antihypertensive peptides, with emphasis on mechanisms of action, molecular stability, bioavailability, and functional food applications. PubMed, Scopus, and Web of Science were searched using combined terms related to bioactive or ACE-inhibitory peptides, stability or bioavailability, and alternative protein sources. Original peer-reviewed studies in English evaluating antihypertensive or ACE-inhibitory peptides from plant, marine, insect, fungal, dairy, or terrestrial animal matrices were considered eligible when they reported experimental evidence on activity, stability, transport, or in vivo efficacy. Three reviewers independently screened records and extracted data. A total of 177 studies were included. Plant and marine matrices accounted for approximately 72% of the evidence base, with a strong focus on low-molecular-weight peptides (<3 kDa) and multistage validation pipelines integrating in silico screening, in vitro enzymatic assays, Caco-2 transport models, ex vivo assays, and spontaneously hypertensive rat studies. Overall, the evidence supports the antihypertensive potential of selected food-derived peptides, particularly through ACE inhibition and related vascular mechanisms. Encapsulation and advanced delivery approaches improved peptide stability and bioavailability in several studies. Food-derived antihypertensive peptides represent promising candidates for functional foods and nutraceuticals; however, greater methodological standardization, formal risk-of-bias assessment in primary studies, and well-designed human trials remain necessary to strengthen translation into practice.
Journal Article
Full court pressure
\"Zack's new teammates won't pass to him, and he's being guarded by his former friend, Joey Jacobs, who's the fastest player in the league. Joey wants to make Zack look bad, and he has the skills to do it. Without a doubt, Zack will be facing full court pressure.\"--Page 4 of cover.
Book
Learning time : in pursuit of educational equity
In this book, the authors focus on how learning time--including the nature, quality, and quantity of that time--differs dramatically for affluent children and poor children and also explore a range of ways to improve the quality and quantity of learning time for children in poverty-- Provided by publisher.
Book
Complex behavior from intrinsic motivation to occupy future action-state path space
Most theories of behavior posit that agents tend to maximize some form of reward or utility. However, animals very often move with curiosity and seem to be motivated in a reward-free manner. Here we abandon the idea of reward maximization and propose that the goal of behavior is maximizing occupancy of future paths of actions and states. According to this maximum occupancy principle, rewards are the means to occupy path space, not the goal per se; goal-directedness simply emerges as rational ways of searching for resources so that movement, understood amply, never ends. We find that action-state path entropy is the only measure consistent with additivity and other intuitive properties of expected future action-state path occupancy. We provide analytical expressions that relate the optimal policy and state-value function and prove convergence of our value iteration algorithm. Using discrete and continuous state tasks, including a high-dimensional controller, we show that complex behaviors such as “dancing”, hide-and-seek, and a basic form of altruistic behavior naturally result from the intrinsic motivation to occupy path space. All in all, we present a theory of behavior that generates both variability and goal-directedness in the absence of reward maximization.
Intelligent behavior of artificial agents and their design are usually considered as a reward maximization phenomenon, however, the reward function construction may be challenging. The authors introduce an alternative principle for agents’ behavior and design based on maximizing the occupancy of possible state and action paths.
Journal Article
Antioxidant, antihypertensive, anti-hyperglycemic, and antimicrobial activity of aqueous extracts from twelve native plants of the Yucatan coast
Looking for a biotechnical potential, aqueous extracts of leaves of 12 native species used in the Mayan traditional medicine of the coastal dune and mangrove of Yucatan (Mexico) were selected to evaluate their biological activities. Rhizophora mangle and Manilkara zapota showed the highest free radical scavenging activity (3.94 ± 0.19 and 6.42 ± 0.32 μg/mL, respectively), and the highest antihypertensive activity was obtained from Solanum donianum (0.38 μg/mL). The anti-hyperglycemic activity of these species was also tested; the highest activities were registered with R. mangle. The antimicrobial activity of Malvaviscus arboreus, S. donianum, M. zapota, and R. mangle at 10% (w/v) was positive against six human pathogenic bacteria and Bonellia macrocarpa against one pathogenic fungus. Solanum donianum, M. zapota, B. macrocarpa, and R. mangle were positive against two pathogenic plant fungi. These results show that the aqueous extracts of five native plants of the Yucatan coast have potential as antioxidants, ACE inhibitors, α-amylase and α-glucosidase inhibitors, and as antimicrobials, which make their exploration for utilization in the agricultural and pharmaceutical industries a possibility.
Journal Article
Effect of Working Fluid-Filling Ratio Combination on Thermosyphon Performance as Add-In Enhancer for Indoor Air Conditioning Devices
An experimental study is presented to account for the implementation of a two-phase closed thermosyphon pipe, for energy-saving purposes, in air conditioning systems in the context of COVID-19. The experimental setup consisted of a 0.5 m × 0.0127 m type L copper pipe which was employed as the body of the heat exchanger; an electric resistance heater of 0.1 m length located at the bottom; and a 0.25 m length water-cooled concentric condenser located at the top. The evaluation was conducted employing acetone, ethanol, and distilled water as working fluids; ranging the heat supplied at the evaporator from 25 to 125 W and the filling ratio from 20% to 40% of the total inner volume of the thermosyphon. From the data obtained, it was found that ethanol is the working fluid most susceptible to changes in operation conditions. Contrarily, distilled water was found to deliver consistent performance, up to a point that, for the analysed setup, it is considered to be independent of both, heat flow supplied at the evaporator and thermosyphon filling ratio. Meanwhile, acetone was found to be the only fluid tested that displays a directly proportional behaviour between heat absorption and dissipation. From compiling experimental data, response surfaces were constructed and used as direct and rough optimization tools. The information provided by this approach is considered to be particularly useful and is introduced for modelling and design purposes. Based on the results, it was found that acetone, within operation ranges of 34%<ϕ<40% and 75 W
Journal Article
SodSAR: A Tower-Based 1–10 GHz SAR System for Snow, Soil and Vegetation Studies
We introduce SodSAR, a fully polarimetric tower-based wide frequency (1–10 GHz) range Synthetic Aperture Radar (SAR) aimed at snow, soil and vegetation studies. The instrument is located in the Arctic Space Centre of the Finnish Meteorological Institute in Sodankylä, Finland. The system is based on a Vector Network Analyzer (VNA)-operated scatterometer mounted on a rail allowing the formation of SAR images, including interferometric pairs separated by a temporal baseline. We present the description of the radar, the applied SAR focusing technique, the radar calibration and measurement stability analysis. Measured stability of the backscattering intensity over a three-month period was observed to be better than 0.5 dB, when measuring a target with a known radar cross section. Deviations of the estimated target range were in the order of a few cm over the same period, indicating also good stability of the measured phase. Interforometric SAR (InSAR) capabilities are also discussed, and as a example, the coherence of subsequent SAR acquisitions over the observed boreal forest stand are analyzed over increasing temporal baselines. The analysis shows good conservation of coherence in particular at L-band, while higher frequencies are susceptible to loss of coherence in particular for dense vegetation. The potential of the instrument for satellite calibration and validation activities is also discussed.
Journal Article