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Background: The present study aimed to assess of quality of life and self-esteem and to discover the relation of both to the clinical and therapeutic parameters in children with hemophilia. To achieve this target, 100 hemophilic children were included in the study. They had a mean age of 10.09+ 4.44. They were subjected to careful history taking and thorough dinical examination. In addition, they were subjected QOL and self-esteem assessment. It was shown that 48% of the studied children are obese, the most commonly encountered manifestation was target joint 75.0% followed by gum bleeding 72%, circumcision bleeding 69.0%, epistaxis 54.0%, hemartherosis 50.0% muscle hematoma 49.0%, dental bleeding 45%, and limited joint movement 33.0%. Regarding the QOL, the present study found that it is clear that the studied children had generally poor quality of life domain. This is manifested by the mean total QOL score which is only 50.9, comparison between individual and total QOL scores in the studied age groups had revealed that children of the middle age had significantly better QOL scores when compared with the other two groups The relatively poor QOL scores in the present study is explained by the higher frequency of joint problems which had detrimental effects on the studied children physical health and other QOL domains. Also patients with joint problems including hemartherosis. target joint and limited joint movement had significantly worse QOL score when compared with patients without, assessing patients self- esteem reveled significantly lower Coppersmith self- esteem inventory in patients when compared with controls, obese children had significantly lower self-esteem scores when compared with children with normal weight Finally, we showed a statistically significant inverse correlation between self-esteem and QOL.

People with mental disorders face stigma, discrimination and marginalization in most societies . Attitudes influence both professional and personal behavior. In particular, stigma and discrimination associated with mental illness results in the under-use of mental health services. Objectives: Studying the attitude towards the mentally ill among non medical employees in psychiatric hospitals in two different countries Egypt (group A) and Kuwait (group B). Investigating whether or not working in Psychiatric Hospitals can affect the attitudes to those patients and whether or not there stands a cultural difference in such attitudes. Methodology: Non medical psychiatric staff working in hospital; a total number of 347 employees and workers participated in the study, while the number of drop outs was about 46 employees who refused to complete the interview. All subjects fulfilled the following: Fahmy and El-Sherbini Social Classification and Assessment of attitudes towards mental illnesses using (CAMI) scale. Results: It was noticed that higher CAMI scores were found in group B and there was a very highly statistical significance between both groups regarding total scores, fear and exclusion and goodwill. Regarding correlation with various demographic data revealed the following age was not differing statistically in both groups, Sex was found to have a statistical significance in group A concerning social control (p=0.04) and fear and exclusion scores in group B (p=0.007). Education was found to influence social control in group A (p=0.007) and influencing all the subscales of CAMI in group B. Professional workers including nurses and security team were found to have a positive effect on attitude evident in scoring less in fear and exclusion subscale and was statistically different in both group A and B (p=0.03; 0.000) respectively; also occupation influences the total scores in group B (p=0.007) and influence good will in both groups. Finally social class revealed that higher social class individuals hold a better attitude than other classes in both groups Conclusion: general public's view about mental illness is largely unfavorable, the study revealed that attitude of non medical employees in psychiatric hospital toward mentally ill patients is not better than general public attitude despite their continuous contact with this category of patients. Education about mental illness and fighting stigma which affect attitudes of people toward mentally ill is highly needed.